{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:50:09Z","timestamp":1777917009261,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Women's Health"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Data regarding pregnancy and perinatal outcomes of oocyte donation (OD) recipients older than age 45 are limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A total of 459,528 singleton pregnancies with 946 OD pregnancies and 458,582 spontaneous pregnancies were grouped according to maternal age \u226545 years and &lt;45 years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The mean maternal age of the OD recipients was 47.6 for patients &gt;45 and 40.7 for patients \u226445 (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001). Among the spontaneous conceptions, the mean maternal age was 47.8 years for patients &gt;45 and 31.1 for patients \u226445 (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001). Multivariable logistic regression for preterm birth (PTB) &lt;37 weeks and for small gestational age (SGA) among the OD recipients demonstrated that age &gt;45 is a protective factor for PTB &lt;37 weeks (odds ratio [OR]: 0.6, 95% confidence interval [CI]: 0.4\u20130.9,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.03) and for SGA (OR: 0.3, 95% CI: 0.1\u20130.7,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.006, respectively). Among the spontaneous group, age &gt;45 is a risk factor for PTB &lt;37 weeks (OR: 3.2, 95% CI: 2.7\u20133.9,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001), PTB &lt;34 weeks (OR: 4.7, 95% CI: 3.4\u20136.4,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001), SGA (OR: 1.6, 95% CI: 1.2\u20132.1,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001), and pregnancy-induced hypertension (OR: 3.1, 95% CI: 2.1\u20134.7,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001). Other obstetric complications were comparable between the age-groups of the oocyte recipients but were higher among patients &gt;45 years who conceived spontaneously.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>As opposed to spontaneous pregnancies, OD pregnancies of recipients &gt;45 are not associated with higher rates of obstetric or perinatal morbidity compared with younger recipients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/jwh.2024.0552","type":"journal-article","created":{"date-parts":[[2025,2,17]],"date-time":"2025-02-17T03:16:22Z","timestamp":1739762182000},"page":"1084-1089","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Advanced Maternal Age and Pregnancy Outcomes in Oocyte Donation and Spontaneous Pregnancies: A Large Population-Based Cohort Study"],"prefix":"10.1177","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3947-7717","authenticated-orcid":false,"given":"Roni","family":"Rahav-Koren","sequence":"first","affiliation":[{"name":"IVF Unit, Department of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba, Israel."},{"name":"Faculty of Medical &amp; Health Sciences, Tel Aviv University, Tel Aviv, Israel."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hila","family":"Shalev-Ram","sequence":"additional","affiliation":[{"name":"IVF Unit, Department of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba, Israel."},{"name":"Faculty of Medical &amp; Health Sciences, Tel Aviv University, Tel Aviv, Israel."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9930-0051","authenticated-orcid":false,"given":"Einat","family":"Haikin-Herzberger","sequence":"additional","affiliation":[{"name":"IVF Unit, Department of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba, Israel."},{"name":"Faculty of Medical &amp; Health Sciences, Tel Aviv University, Tel Aviv, Israel."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mattan","family":"Levi","sequence":"additional","affiliation":[{"name":"IVF Unit, Department of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba, Israel."},{"name":"Faculty of Medical &amp; Health Sciences, Tel Aviv University, Tel Aviv, Israel."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir","family":"Wiser","sequence":"additional","affiliation":[{"name":"IVF Unit, Department of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba, Israel."},{"name":"Faculty of Medical &amp; Health Sciences, Tel Aviv University, Tel Aviv, Israel."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Netanella","family":"Miller","sequence":"additional","affiliation":[{"name":"IVF Unit, Department of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba, Israel."},{"name":"Faculty of Medical &amp; Health Sciences, Tel Aviv University, Tel Aviv, Israel."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,9,10]]},"reference":[{"key":"e_1_3_9_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/307174a0"},{"key":"e_1_3_9_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deac105.057"},{"key":"e_1_3_9_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2016.07.002"},{"key":"e_1_3_9_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2014.04.027"},{"key":"e_1_3_9_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmw012"},{"key":"e_1_3_9_7_2","doi-asserted-by":"publisher","DOI":"10.1515\/jpm.2010.084"},{"key":"e_1_3_9_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajogmf.2023.100885"},{"key":"e_1_3_9_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2016.09.021"},{"key":"e_1_3_9_10_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0096237"},{"key":"e_1_3_9_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2020.07.005"},{"key":"e_1_3_9_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2013.01.128"},{"key":"e_1_3_9_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.14257"},{"key":"e_1_3_9_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/13.2.483"},{"key":"e_1_3_9_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-019-01552-4"},{"key":"e_1_3_9_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2015.03.004"},{"key":"e_1_3_9_17_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0031-1285101"},{"issue":"5","key":"e_1_3_9_18_2","first-page":"311","article-title":"Birth weight standards in the live-born population in Israel","volume":"7","author":"Dollberg S","year":"2005","unstructured":"Dollberg S, , Haklai Z, , Mimouni FB, et al. 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