{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:58:55Z","timestamp":1777921135921,"version":"3.51.4"},"reference-count":39,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Laparoendoscopic &amp; Advanced Surgical Techniques"],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>The aim of this meta-analysis was to determine whether laparoscopic splenectomy (LS) and LS with esophagogastric devascularization (LSED) were the minimally invasive alternative for portal hypertension.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A meta-analysis of comparative clinical trials was performed to assess our questions noted above. The databases PubMed, ScienceDirect, and Springerlink were searched.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      In total, 725 patients with liver cirrhosis and\/or portal hypertension from eight published comparative trials were included. The operation time in the laparoscopic group was more than that in the open group [weighted mean difference (WMD) 35.24 (16.74, 53.74);\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;.001]. However, there were less intraoperative blood loss [WMD \u2212194.84 (\u2212321.34, \u221268.34);\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =.003] and a shorter postoperative hospital stay [WMD \u22124.33 (\u22125.30, \u22123.36);\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;.001] in the laparoscopic group. The incidence of complications was similar in the two groups. In the subgroup studies about LS versus open splenectomy, no significant differences were found in operation time, intraoperative blood loss, and complication rates. The postoperative hospital stay in the LS group was apparently decreased [WMD \u22124.07 (\u22124.93, \u22123.21);\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;.001]. Although the operation time of LSED was longer [WMD 43.23 (17.13, 69.32);\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =.001], LSED was associated with less intraoperative blood loss [WMD \u2212189.26 (\u2212295.71, \u221282.81);\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;.001] and a shorter postoperative hospital stay [WMD \u22125.41 (\u22127.84, \u22122.98);\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;.001]. Meta-analysis did not favor either LSED or open splenectomy with esophagogastric devascularization in term of complication rates.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The results of this meta-analysis were in favor of LS and LSED for being a safe, minimally invasion alternative for patients with liver cirrhosis and portal hypertension.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/lap.2014.0506","type":"journal-article","created":{"date-parts":[[2015,2,15]],"date-time":"2015-02-15T10:15:52Z","timestamp":1423995352000},"page":"103-111","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["A Meta-analysis Study of Laparoscopic Versus Open Splenectomy With or Without Esophagogastric Devascularization in the Management of Liver Cirrhosis and Portal Hypertension"],"prefix":"10.1177","volume":"25","author":[{"given":"Xin","family":"Zheng","sequence":"first","affiliation":[{"name":"The First Affiliated Hospital of Xi'an Jiaotong University","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changwei","family":"Dou","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Xi'an Jiaotong University","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingmin","family":"Yao","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Xi'an Jiaotong University","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingguang","family":"Liu","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Xi'an Jiaotong University","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2015,2]]},"reference":[{"key":"e_1_3_3_2_2","first-page":"303","article-title":"Endoscopic submucosal dissection of gastric neoplastic lesions in patients with liver cirrhosis: A systematic review","volume":"21","author":"Repici A","year":"2012","unstructured":"Repici A, , Pagano N, , Hassan C, et al. 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