{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:02:41Z","timestamp":1777921361454,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Laparoendoscopic &amp; Advanced Surgical Techniques"],"published-print":{"date-parts":[[2019,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The aim of this report was dual: (a) to describe the step-by-step standardized intraoperative percutaneous injection of carbon nanoparticles (CNPs) procedure for CNP-stained central compartment lymph nodes (CLNs) and passive display of parathyroid gland by CNP-stained thyroid in endoscopic thyroidectomy via bilateral areola approach (ETBAA) and (b) evaluation and outcomes of percutaneous injection of CNPs in total thyroidectomy plus CLN dissection through ETBAA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Video describes the technique of intraoperative percutaneous injection of CNPs for central compartment LNs identification, dissection, and parathyroid glands preservation in ETBAA for papillary thyroid cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/journals.sagepub.com\/doi\/suppl\/10.1089\/lap.2019.0102\">Supplementary video<\/jats:ext-link>\n                      shows that after intrathyroid injection of CNPs, black carbon can be seen rapidly along the lymphatic vessels to the surrounding LNs. Parathyroid gland can be passive display when the thyroid is black and the parathyroid gland is normal in color. Intraoperative neuromonitoring (Medtronic\n                      <jats:sup>\u00ae<\/jats:sup>\n                      NIM-Response 3.0) was applied to identify recurrent laryngeal nerve and external branch of superior laryngeal nerve. No patient had any side effects of CNPs from 152 patients followed up for an average of 19.6 months (6\u201334 months). LNs were easily found under ETBAA. The accuracy of black-dyed LN in thyroid cancers was 95.9% (1016\/1059). The number of parathyroid glands passive display was 69.9% (267\/382).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>It is feasible to use CNPs to show CLNs in thyroid cancer during ETBAA. CNP suspension is safe for thyroidal injection.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/lap.2019.0102","type":"journal-article","created":{"date-parts":[[2019,4,2]],"date-time":"2019-04-02T12:22:19Z","timestamp":1554207739000},"page":"1038-1041","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Application of Carbon Nanoparticles in Endoscopic Thyroidectomy via Bilateral Areola Approach: Total Thyroidectomy Plus Central Lymph Node Dissection"],"prefix":"10.1177","volume":"29","author":[{"given":"Daqi","family":"Zhang","sequence":"first","affiliation":[{"name":"Division of Thyroid Surgery, Jilin Provincial Key Laboratory of Surgical Translational Medicine, Jilin Provincial Precision Medicine Laboratory of Molecular Biology and Translational Medicine on Differentiated Thyroid Carcinoma, China-Japan Union Hospital of Jilin University, Changchun City, Jilin Province, P. R. China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tie","family":"Wang","sequence":"additional","affiliation":[{"name":"Division of Thyroid Surgery, Jilin Provincial Key Laboratory of Surgical Translational Medicine, Jilin Provincial Precision Medicine Laboratory of Molecular Biology and Translational Medicine on Differentiated Thyroid Carcinoma, China-Japan Union Hospital of Jilin University, Changchun City, Jilin Province, P. R. China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianlorenzo","family":"Dionigi","sequence":"additional","affiliation":[{"name":"Division for Endocrine and Minimally Invasive Surgery, Department of Human Pathology in Adulthood and Childhood \u201cG. Barresi,\u201d University Hospital G. Martino, University of Messina, Messina, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yantao","family":"Fu","sequence":"additional","affiliation":[{"name":"Division of Thyroid Surgery, Jilin Provincial Key Laboratory of Surgical Translational Medicine, Jilin Provincial Precision Medicine Laboratory of Molecular Biology and Translational Medicine on Differentiated Thyroid Carcinoma, China-Japan Union Hospital of Jilin University, Changchun City, Jilin Province, P. R. China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Division of Thyroid Surgery, Jilin Provincial Key Laboratory of Surgical Translational Medicine, Jilin Provincial Precision Medicine Laboratory of Molecular Biology and Translational Medicine on Differentiated Thyroid Carcinoma, China-Japan Union Hospital of Jilin University, Changchun City, Jilin Province, P. R. China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yishen","family":"Zhao","sequence":"additional","affiliation":[{"name":"Division of Thyroid Surgery, Jilin Provincial Key Laboratory of Surgical Translational Medicine, Jilin Provincial Precision Medicine Laboratory of Molecular Biology and Translational Medicine on Differentiated Thyroid Carcinoma, China-Japan Union Hospital of Jilin University, Changchun City, Jilin Province, P. R. China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingting","family":"Li","sequence":"additional","affiliation":[{"name":"Division of Thyroid Surgery, Jilin Provincial Key Laboratory of Surgical Translational Medicine, Jilin Provincial Precision Medicine Laboratory of Molecular Biology and Translational Medicine on Differentiated Thyroid Carcinoma, China-Japan Union Hospital of Jilin University, Changchun City, Jilin Province, P. R. China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Sun","sequence":"additional","affiliation":[{"name":"Division of Thyroid Surgery, Jilin Provincial Key Laboratory of Surgical Translational Medicine, Jilin Provincial Precision Medicine Laboratory of Molecular Biology and Translational Medicine on Differentiated Thyroid Carcinoma, China-Japan Union Hospital of Jilin University, Changchun City, Jilin Province, P. R. China."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,8,7]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.3233\/CBM-181386"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000011778"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-30299-8"},{"key":"e_1_3_6_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000011364"},{"key":"e_1_3_6_6_2","first-page":"447","article-title":"Carbon nanoparticles guide contralateral central neck dissection in patients with papillary thyroid cancer","volume":"16","author":"Yu W","year":"2018","unstructured":"Yu W, , Xu G, , Sun J, , Zhong N. Carbon nanoparticles guide contralateral central neck dissection in patients with papillary thyroid cancer. Oncol Lett, 2018; 16:447\u2013452.","journal-title":"Oncol Lett"},{"key":"e_1_3_6_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000008380"},{"key":"e_1_3_6_8_2","doi-asserted-by":"publisher","DOI":"10.2147\/OTT.S131012"},{"key":"e_1_3_6_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000006285"},{"key":"e_1_3_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2016.10.037"},{"key":"e_1_3_6_11_2","doi-asserted-by":"publisher","DOI":"10.1177\/1553350616668088"}],"container-title":["Journal of Laparoendoscopic &amp; Advanced Surgical Techniques"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/lap.2019.0102","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/lap.2019.0102","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/lap.2019.0102","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T19:52:35Z","timestamp":1777665155000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/lap.2019.0102"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,1]]},"references-count":10,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,8,1]]}},"alternative-id":["10.1089\/lap.2019.0102"],"URL":"https:\/\/doi.org\/10.1089\/lap.2019.0102","relation":{},"ISSN":["1092-6429","1557-9034"],"issn-type":[{"value":"1092-6429","type":"print"},{"value":"1557-9034","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,1]]}}}