{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T03:42:43Z","timestamp":1792726963437,"version":"4.5.0"},"reference-count":24,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Laparoendoscopic &amp; Advanced Surgical Techniques"],"published-print":{"date-parts":[[2021,6,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Delayed gastric emptying (DGE) is a common complication after esophagectomy with gastric tube reconstruction. It is still unclear whether a pyloric drainage procedure might reduce the risk of DGE.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We identified in our database all patients subjected to Ivor Lewis esophagectomy after neoadjuvant chemoradiotherapy in the period 2000\u20132012. In the period 2000\u20132009, we performed a routine pyloroplasty (pyloroplasty group, PP group, 15 patients), after 2009 we did not perform any type of pyloric drainage procedure (nonpyloroplasty group, NPP group, 11 patients). We compared the groups with subjective questionnaires to assess the perceived quality of life (QoL) (QLQ-C30 and OES-18) and with objective test to study the gastric tube emptying (timed barium swallow test, scintigraphy, 24 hours' pH-metry).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      No difference was observed in questionnaires QLC-C30 and OES-18 scores: 73% of patients in PP group and 63% in NPP group scored their overall QoL as good to excellent (QLC-C30). We did not report difference in timed barium swallow test results and in scintigraphy results. Twenty-four-hour pH-metry results showed in PP group a nonsignificant higher number of acid reflux episodes (NPP group 23.2\u2009\u00b1\u20099.5 versus PP group 41.3\u2009\u00b1\u200910.7,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.29) and a longer time with pH &lt;4 (NPP group 0.89%\u2009\u00b1\u20091.6% versus PP group 3.1%\u2009\u00b1\u20092.1%,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.24).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>In our series, pyloroplasty was not associated with improved long-term QoL nor with better gastric conduit emptying. Further studies are needed to confirm these findings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/lap.2020.0595","type":"journal-article","created":{"date-parts":[[2020,9,8]],"date-time":"2020-09-08T17:08:45Z","timestamp":1599584925000},"page":"692-697","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Effect of Pyloroplasty on Gastric Conduit Emptying and Patients' Quality of Life After Ivor Lewis Esophagectomy"],"prefix":"10.1177","volume":"31","author":[{"given":"Carlo Alberto","family":"De Pasqual","sequence":"first","affiliation":[{"name":"Division of General and Upper GI Surgery, Department of Surgery, University of Verona, Verona, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacopo","family":"Weindelmayer","sequence":"additional","affiliation":[{"name":"Division of General and Upper GI Surgery, Department of Surgery, University of Verona, Verona, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Gobbi","sequence":"additional","affiliation":[{"name":"Division of General and Upper GI Surgery, Department of Surgery, University of Verona, Verona, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Alberti","sequence":"additional","affiliation":[{"name":"Division of General and Upper GI Surgery, Department of Surgery, University of Verona, Verona, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Veltri","sequence":"additional","affiliation":[{"name":"Division of General and Upper GI Surgery, Department of Surgery, University of Verona, Verona, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Giacopuzzi","sequence":"additional","affiliation":[{"name":"Division of General and Upper GI Surgery, Department of Surgery, University of Verona, Verona, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"de Manzoni","sequence":"additional","affiliation":[{"name":"Division of General and Upper GI Surgery, Department of Surgery, University of Verona, Verona, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,6,2]]},"reference":[{"key":"e_1_3_5_2_2","unstructured":"Standring S. 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Delayed postoperative emptying after esophageal resection is dependent on the size of the gastric substitute. 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