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We report our experience and review the current literature focusing on surgical management and outcomes of children affected by WS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Data regarding demographics, clinical manifestations, diagnosis, and treatment of children treated for WS at our Institution were analyzed. Systematic review was registered on Prospero (CRD42018089971). Scientific databases were searched using defined keywords. Articles were selected using predefined exclusion and inclusion criteria. Analysis was conducted adding our center's cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>One hundred sixty-six articles were included in the review, 197 cases were analyzed, 3 of which unpublished. Female\/male ratio was 1.5:1 and median age at diagnosis was 8 years. Most frequent clinical manifestation was isolated abdominal pain (42.6%). Torsion of splenic pedicle was diagnosed in 56.3%. Among surgical procedures, 39% underwent splenopexy and 54.8% underwent splenectomy. In case of splenopexy, the most commonly used techniques were using of a mesh (45.5%) or creation of a retroperitoneal pouch (30.9%). In 48.2% of splenopexies, minimally invasive surgery (MIS) was used. Splenopexy was effective in 94.8% (88% considering only cases with a spleen torsion).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>WS is a rare condition potentially leading to torsion of the spleen. This entity has to be kept in mind as a differential diagnosis in case of abdominal pain. Splenopexy should be the treatment of choice; its success rate in terms of preserved spleens can be affected by the presence of a torted organ. Retroperitoneal pouch or mesh fixation are the most preferred techniques. Authors recommend MIS approach.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/lap.2020.0759","type":"journal-article","created":{"date-parts":[[2021,1,11]],"date-time":"2021-01-11T20:46:22Z","timestamp":1610397982000},"page":"468-477","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Surgical Approach of Wandering Spleen in Infants and Children: A Systematic Review"],"prefix":"10.1177","volume":"31","author":[{"given":"Alba","family":"Ganarin","sequence":"first","affiliation":[{"name":"Pediatric Surgery Unit, Department of Women's and Children's Health, University Hospital of Padova, Padova, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Fascetti Leon","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Unit, Department of Women's and Children's Health, University Hospital of Padova, Padova, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrico","family":"La Pergola","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Unit, Department of Women's and Children's Health, University Hospital of Padova, Padova, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piergiorgio","family":"Gamba","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Unit, Department of Women's and Children's Health, University Hospital of Padova, Padova, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,4,1]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-012-1880-x"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00276-017-1893-0"},{"key":"e_1_3_4_4_2","first-page":"31","article-title":"A wandering spleen presenting as a hypogastric mass: Case report","volume":"11","author":"Bouassida M","year":"2012","unstructured":"Bouassida M, , Sassi S, , Chtourou MF, et al. 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