{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:06:45Z","timestamp":1777921605193,"version":"3.51.4"},"reference-count":22,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Laparoendoscopic &amp; Advanced Surgical Techniques"],"published-print":{"date-parts":[[2022,12,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Minimally invasive surgery (MIS) is increasingly used for repair of congenital diaphragmatic hernia (CDH). Reported recurrence after MIS repair varies and is limited by short follow-up and low volume. Our objective was to compare recurrence after MIS versus open repair of CDH.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Infants who underwent CDH repair between 2010 and 2020 were identified using the PearlDiver Mariner database, a national patient claims data set allowing longitudinal follow-up of patients across systems. Kaplan\u2013Meier analysis and Cox proportional hazards regression models were used to evaluate the association of surgical approach (MIS versus open) and use of a patch with time to recurrence while adjusting for comorbidities (congenital heart disease and pulmonary hypertension) and length of stay (LOS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      In a cohort of 629 infants, 25.6% (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u2009161) underwent MIS repair with a median follow-up of 4.8 years and recurrence rate of 38.6% (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u2009243). Rates of recurrence after MIS repair were lower than open (5 years: 38.6% versus 44.3%;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.03) and higher with use of patch (5 years: 60.1% versus 40.1%;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.02). After adjustment for comorbidities and LOS as a proxy for patient complexity, there was no significant difference in recurrence based on approach (adjusted hazard ratio [aHR]: 0.79; confidence interval [95% CI]: 0.57\u20131.10;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.16) or use of patch (aHR: 1.22; 95% CI: 0.83\u20131.79;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.32).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Recurrence rates after repair of CDH were not different based on surgical approach or use of patch after adjustment. Previous data were likely biased by patient complexity, and surgeons should consider these factors in determining approach.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/lap.2022.0236","type":"journal-article","created":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T15:17:36Z","timestamp":1664205456000},"page":"1228-1233","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Minimally Invasive Approaches and Use of a Patch Are Not Associated with Increased Recurrence Rates After Congenital Diaphragmatic Hernia Repair"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4922-7041","authenticated-orcid":false,"given":"Gwyneth A.","family":"Sullivan","sequence":"first","affiliation":[{"name":"Division of Pediatric Surgery, Department of Surgery, Rush University Medical Center, Chicago, Illinois, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6492-1464","authenticated-orcid":false,"given":"Nicholas J.","family":"Skertich","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Department of Surgery, Rush University Medical Center, Chicago, Illinois, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacky","family":"Kwong","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Department of Surgery, Rush University Medical Center, Chicago, Illinois, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grant","family":"Owen","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Department of Surgery, Rush University Medical Center, Chicago, Illinois, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Srikumar","family":"Pillai","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Department of Surgery, Rush University Medical Center, Chicago, Illinois, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary Beth","family":"Madonna","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Department of Surgery, Rush University Medical Center, Chicago, Illinois, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ami N.","family":"Shah","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Department of Surgery, Rush University Medical Center, Chicago, Illinois, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian C.","family":"Gulack","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Department of Surgery, Rush University Medical Center, Chicago, Illinois, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,12,8]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(95)00100-Y"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.1089\/lap.2016.0247"},{"issue":"2","key":"e_1_3_6_4_2","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1055\/s-0040-1702222","article-title":"Thoracoscopic repair of congenital diaphragmatic hernia","volume":"30","author":"Wagner R","year":"2020","unstructured":"Wagner R, , Mayer S, , Feng X, et al. Thoracoscopic repair of congenital diaphragmatic hernia. Eur J Pediatr Surg, 2020; 30,(2):137\u2013141; doi: 10.1055\/s-0040-1702222","journal-title":"Eur J Pediatr Surg"},{"key":"e_1_3_6_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-015-1222-3"},{"key":"e_1_3_6_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13019-019-0938-3"},{"key":"e_1_3_6_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10029-015-1423-0"},{"key":"e_1_3_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2014.02.049"},{"key":"e_1_3_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2020.09.018"},{"key":"e_1_3_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2017.03.011"},{"key":"e_1_3_6_11_2","doi-asserted-by":"publisher","DOI":"10.1089\/lap.2011.0356"},{"key":"e_1_3_6_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-015-3765-1"},{"key":"e_1_3_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2011.03.050"},{"key":"e_1_3_6_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000005035"},{"key":"e_1_3_6_15_2","first-page":"10","article-title":"Shortened course of amoxicillin\/clavulanate is preferred antibiotic treatment after surgery for perforated appendicitis in children","author":"Skertich NJ","year":"2022","unstructured":"Skertich NJ, , Sullivan GA, , Wiegmann AL, et al. Shortened course of amoxicillin\/clavulanate is preferred antibiotic treatment after surgery for perforated appendicitis in children. J Pediatr Surg, 2022; doi: 10.1016\/j.jpedsurg.2022.03.032","journal-title":"J Pediatr Surg"},{"key":"e_1_3_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2013.08.014"},{"key":"e_1_3_6_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2008.11.030"},{"key":"e_1_3_6_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2010.02.017"},{"key":"e_1_3_6_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2013.02.005"},{"key":"e_1_3_6_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2016.12.050"},{"key":"e_1_3_6_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2012.11.012"},{"key":"e_1_3_6_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2009.10.028"},{"key":"e_1_3_6_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2019.10.021"}],"container-title":["Journal of Laparoendoscopic &amp; Advanced Surgical Techniques"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/lap.2022.0236","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/lap.2022.0236","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/lap.2022.0236","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T19:57:32Z","timestamp":1777665452000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/lap.2022.0236"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,1]]},"references-count":22,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12,1]]}},"alternative-id":["10.1089\/lap.2022.0236"],"URL":"https:\/\/doi.org\/10.1089\/lap.2022.0236","relation":{},"ISSN":["1092-6429","1557-9034"],"issn-type":[{"value":"1092-6429","type":"print"},{"value":"1557-9034","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,1]]}}}