{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:06:48Z","timestamp":1777921608700,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Laparoendoscopic &amp; Advanced Surgical Techniques"],"published-print":{"date-parts":[[2022,12,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Cryoablation of intercostal nerves is performed for pain control after minimally invasive repair of pectus excavatum (MIRPE). Cryoablation affects both sensory and motor neurons, resulting in temporary anesthesia to the chest wall and loss of intercostal motor function. The study objective is to determine the effect of cryoablation on incentive spirometry (IS) volumes, as a measure of pulmonary function, after MIRPE.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A single-institution retrospective review of pediatric patients undergoing MIRPE was performed. All patients received a multimodal regimen (MMR) of analgesics postoperatively. Three groups were compared\u2014cryoablation (CRYO), elastomeric pain pump (EPP), and MMR alone. The primary outcomes were postoperative IS volumes and IS volumes as a ratio of preoperative forced vital capacity (FVC). Secondary outcomes included pain scores, opioid use, length of stay (LOS), and infectious complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      MIRPE was performed in 115 patients: 50 CRYO, 50 EPP, and 15 MMR alone. Groups were similar for demographics and pectus excavatum severity. Postoperative spirometry measurements were similar across groups: IS (CRYO 750\u2009mL [500,961] versus EPP 750\u2009mL [590,1019] versus MMR 696\u2009mL [500,1037],\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.77); IS\/FVC (CRYO 0.19 [0.14,0.26] versus EPP 0.20 [0.16,0.26] versus MMR 0.16 [0.15,0.24],\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.69). Although pain scores were also similar across groups, CRYO patients used less opioid (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u2009.05) and had shorter LOS (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u2009.05). Postoperative pneumonia was rare and similar across groups (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20091.00).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Intercostal nerve cryoablation during MIRPE does not adversely affect postoperative IS volumes or increase pneumonia rate, despite the temporary loss of motor innervation to intercostal muscles. Cryoablation provides effective pain control with less opioid use.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/lap.2022.0242","type":"journal-article","created":{"date-parts":[[2022,11,9]],"date-time":"2022-11-09T11:47:25Z","timestamp":1667994445000},"page":"1244-1248","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Intercostal Nerve Cryoablation in Minimally Invasive Repair of Pectus Excavatum: Effect on Pulmonary Function"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5597-3158","authenticated-orcid":false,"given":"Krista","family":"Lai","sequence":"first","affiliation":[{"name":"Division of Pediatric Surgery, Phoenix Children's Hospital, Phoenix, Arizona, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justin","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Phoenix Children's Hospital, Phoenix, Arizona, USA."},{"name":"Department of Child Health, University of Arizona College of Medicine\u2013Phoenix, Phoenix, Arizona, USA."},{"name":"Department of Surgery, Mayo Clinic College of Medicine and Science, Phoenix, Arizona, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David M.","family":"Notrica","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Phoenix Children's Hospital, Phoenix, Arizona, USA."},{"name":"Department of Child Health, University of Arizona College of Medicine\u2013Phoenix, Phoenix, Arizona, USA."},{"name":"Department of Surgery, Mayo Clinic College of Medicine and Science, Phoenix, Arizona, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Craig","family":"Egan","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Phoenix Children's Hospital, Phoenix, Arizona, USA."},{"name":"Department of Child Health, University of Arizona College of Medicine\u2013Phoenix, Phoenix, Arizona, USA."},{"name":"Department of Surgery, Mayo Clinic College of Medicine and Science, Phoenix, Arizona, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa E.","family":"McMahon","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Phoenix Children's Hospital, Phoenix, Arizona, USA."},{"name":"Department of Child Health, University of Arizona College of Medicine\u2013Phoenix, Phoenix, Arizona, USA."},{"name":"Department of Surgery, Mayo Clinic College of Medicine and Science, Phoenix, Arizona, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark S.","family":"Molitor","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Phoenix Children's Hospital, Phoenix, Arizona, USA."},{"name":"Department of Child Health, University of Arizona College of Medicine\u2013Phoenix, Phoenix, Arizona, USA."},{"name":"Department of Surgery, Mayo Clinic College of Medicine and Science, Phoenix, Arizona, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae-O","family":"Bae","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Phoenix Children's Hospital, Phoenix, Arizona, USA."},{"name":"Department of Child Health, University of Arizona College of Medicine\u2013Phoenix, Phoenix, Arizona, USA."},{"name":"Department of Surgery, Mayo Clinic College of Medicine and Science, Phoenix, Arizona, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel J.","family":"Ostlie","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Phoenix Children's Hospital, Phoenix, Arizona, USA."},{"name":"Department of Child Health, University of Arizona College of Medicine\u2013Phoenix, Phoenix, Arizona, USA."},{"name":"Department of Surgery, Mayo Clinic College of Medicine and Science, Phoenix, Arizona, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin E.","family":"Padilla","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Phoenix Children's Hospital, Phoenix, Arizona, USA."},{"name":"Department of Child Health, University of Arizona College of Medicine\u2013Phoenix, Phoenix, Arizona, USA."},{"name":"Department of Surgery, Mayo Clinic College of Medicine and Science, Phoenix, Arizona, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,12,8]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1089\/lap.2019.0203"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2019.02.057"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2020.10.009"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-020-04778-x"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2021.03.006"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000003532"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00007.2004"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2015.10.084"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.sempedsurg.2018.05.010"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2019.09.021"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.07972"},{"issue":"3","key":"e_1_3_4_13_2","first-page":"219","article-title":"Efficacy of pre-emptive analgesia and continuous extrapleural intercostal nerve block on post-thoracotomy pain and pulmonary mechanics","volume":"35","author":"Richardson J","year":"1994","unstructured":"Richardson J, , Sabanathan S, , Mearns AJ, et al. Efficacy of pre-emptive analgesia and continuous extrapleural intercostal nerve block on post-thoracotomy pain and pulmonary mechanics. J Cardiovasc Surg (Torino), 1994; 35,(3):219\u2013228.","journal-title":"J Cardiovasc Surg (Torino)"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.128.3.1571"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-7940(01)00815-6"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.2004.03896.x"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2019.12.044"},{"key":"e_1_3_4_18_2","first-page":"10","article-title":"In-hospital outcomes of intercostal nerve cryoablation and surgical stabilization of rib fractures","volume":"10","author":"Fernandez CA","year":"2022","unstructured":"Fernandez CA, , Narveson JR, , Niu F, et al. In-hospital outcomes of intercostal nerve cryoablation and surgical stabilization of rib fractures. J Trauma Acute Care Surg, 2022; 10.1097\/TA.0000000000003623; doi: 10.1097\/TA.0000000000003623","journal-title":"J Trauma Acute Care Surg"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/anae.14579"},{"key":"e_1_3_4_20_2","first-page":"S0022","article-title":"Infectious complications of intercostal nerve cryoablation mediated by perioperative hypothermia during pediatric nuss procedure","author":"Bundrant NT","year":"2022","unstructured":"Bundrant NT, , Sayrs LW, , Ostlie D, et al. Infectious complications of intercostal nerve cryoablation mediated by perioperative hypothermia during pediatric nuss procedure. J Pediatr Surg, 2022; S0022-3468(22)00112-9; doi: 10.1016\/j.jpedsurg.2022.01.044","journal-title":"J Pediatr Surg"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1053\/jpsu.2003.50118"},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.1053\/jpsu.2003.50112"}],"container-title":["Journal of Laparoendoscopic &amp; Advanced Surgical Techniques"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/lap.2022.0242","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/lap.2022.0242","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/lap.2022.0242","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T19:57:34Z","timestamp":1777665454000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/lap.2022.0242"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,1]]},"references-count":21,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12,1]]}},"alternative-id":["10.1089\/lap.2022.0242"],"URL":"https:\/\/doi.org\/10.1089\/lap.2022.0242","relation":{},"ISSN":["1092-6429","1557-9034"],"issn-type":[{"value":"1092-6429","type":"print"},{"value":"1557-9034","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,1]]}}}