{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T01:42:47Z","timestamp":1783906967835,"version":"3.55.0"},"reference-count":8,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Laparoendoscopic &amp; Advanced Surgical Techniques"],"published-print":{"date-parts":[[2023,12,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Portal hypertension is a syndrome characterized by increased pressure in the portal vein system and can be caused by impaired blood flow in the portal vein, hepatic veins, or inferior vena cava. The main complications of this condition are bleeding from varicose veins of the esophagus (in our study in 100% of patients), splenomegaly with hypersplenism (in our study in 98% of patients), ascites (in our study in 1 patient). The main goal of treating portal hypertension is to prevent bleeding from esophageal varices. However, today the goal of surgical treatment of portal hypertension in children is not only to prevent the development of bleeding but also the possible restoration of intrahepatic blood flow.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A retrospective analysis of the results of treatment of portal hypertension in 75 children (41 boys, 34 girls) operated in our Center for the period from 2019 to 2022 was carried out. The mean age of the patients was 7\u2009\u00b1\u20091 years. Sixty-nine patients had an extrahepatic form of portal hypertension, and 6 patients had an intrahepatic form (liver fibrosis). In 14 patients (18.6%), the operation was repeated (a vascular shunt was previously applied in another hospital; 4 children were operated on repeatedly).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A good result was obtained in all children, and the risk of bleeding from varicose veins of the esophagus was eliminated. Vascular bypass surgery was performed in all cases: mesoportal bypass in 17 (22.7%) patients, splenorenal bypass in 37 (49.3%) patients, mesocaval bypass in 21 (28%) patients. In 10 (13%) cases, repeated bypass surgery was required due to dysfunction or thrombosis of the previously performed bypass. In 14 (18.6%) patients with mesoportal shunts, blood flow in the liver was completely restored.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The main method of surgical treatment of portal hypertension today is portosystemic bypass surgery, which effectively prevents bleeding from varicose veins of the esophagus. Mesoportal shunting is a definitive treatment for extrahepatic portal hypertension that restores portal perfusion of the liver.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/lap.2022.0404","type":"journal-article","created":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T13:24:55Z","timestamp":1697462695000},"page":"1231-1235","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Surgical Treatment of Portal Hypertension in Children"],"prefix":"10.1177","volume":"33","author":[{"given":"Abdumanap","family":"Alkhasov","sequence":"first","affiliation":[{"name":"\u201cNational Medical Research Center for Children's Health\u201d Federal State Autonomous Institution of the Russian Federation Ministry of Health, Moscow, Russia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Komina","sequence":"additional","affiliation":[{"name":"\u201cNational Medical Research Center for Children's Health\u201d Federal State Autonomous Institution of the Russian Federation Ministry of Health, Moscow, Russia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergey","family":"Ratnikov","sequence":"additional","affiliation":[{"name":"\u201cNational Medical Research Center for Children's Health\u201d Federal State Autonomous Institution of the Russian Federation Ministry of Health, Moscow, Russia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Saveleva","sequence":"additional","affiliation":[{"name":"\u201cNational Medical Research Center for Children's Health\u201d Federal State Autonomous Institution of the Russian Federation Ministry of Health, Moscow, Russia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ekaterina","family":"Romanova","sequence":"additional","affiliation":[{"name":"\u201cNational Medical Research Center for Children's Health\u201d Federal State Autonomous Institution of the Russian Federation Ministry of Health, Moscow, Russia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2029-7820","authenticated-orcid":false,"given":"Aleksey","family":"Gusev","sequence":"additional","affiliation":[{"name":"\u201cNational Medical Research Center for Children's Health\u201d Federal State Autonomous Institution of the Russian Federation Ministry of Health, Moscow, Russia."},{"name":"Peoples Friendship University of Russia (RUDN University), Moscow, Russia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maksim","family":"Lochmatov","sequence":"additional","affiliation":[{"name":"\u201cNational Medical Research Center for Children's Health\u201d Federal State Autonomous Institution of the Russian Federation Ministry of Health, Moscow, Russia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergey","family":"Yatsyk","sequence":"additional","affiliation":[{"name":"\u201cNational Medical Research Center for Children's Health\u201d Federal State Autonomous Institution of the Russian Federation Ministry of Health, Moscow, Russia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Dyakonova","sequence":"additional","affiliation":[{"name":"\u201cNational Medical Research Center for Children's Health\u201d Federal State Autonomous Institution of the Russian Federation Ministry of Health, Moscow, Russia."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,12,4]]},"reference":[{"issue":"141","key":"e_1_3_5_2_2","first-page":"43","article-title":"Portal hypertension in children-28 years of experience in surgical treatment","volume":"12","author":"Yu RA","year":"2017","unstructured":"Yu RA, , Dronov AF, , Rachkov VE, et al. Portal hypertension in children-28 years of experience in surgical treatment. Surg Gastroenterol, 2017; 12(141):43\u201348; Available from: https:\/\/journaldoctor.ru\/catalog\/gastroenterologiya\/portalnaya-gipertenziya\/?lang=ru [Last accessed: October 18, 2022].","journal-title":"Surg Gastroenterol"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.sempedsurg.2012.05.004"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.7196\/SAMJ.6263"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/879163"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.sempedsurg.2012.05.005"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12072-018-9844-3"},{"issue":"2","key":"e_1_3_5_8_2","first-page":"30","article-title":"Surgical treatment of portal hypertension: The state of art. Pirogov Russian Journal of Surgery Khirurgiya","author":"Sherzinger AG","year":"2013","unstructured":"Sherzinger AG, , Zhigalova SB, , Lebzev VM, et al. Surgical treatment of portal hypertension: The state of art. Pirogov Russian Journal of Surgery Khirurgiya. Zurnal im NI Pirogova, 2013;(2):30\u201334. (In Russian.).","journal-title":"Zurnal im NI Pirogova"},{"issue":"1","key":"e_1_3_5_9_2","first-page":"7","article-title":"Portal cavernoma in the era of mesoportal shunt (Rex) and liver transplant in children","volume":"26","author":"Chocarro G","year":"2016","unstructured":"Chocarro G, , Junco PT, , Dominguez E, et al. Portal cavernoma in the era of mesoportal shunt (Rex) and liver transplant in children. Eur J Pediatr Surg, 2016; 26(1):7\u201312; doi: 10.1055\/s-0035-1563402","journal-title":"Eur J Pediatr Surg"}],"container-title":["Journal of Laparoendoscopic &amp; Advanced Surgical Techniques"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/lap.2022.0404","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/lap.2022.0404","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/lap.2022.0404","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T19:57:49Z","timestamp":1777665469000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/lap.2022.0404"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,1]]},"references-count":8,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2023,12,1]]}},"alternative-id":["10.1089\/lap.2022.0404"],"URL":"https:\/\/doi.org\/10.1089\/lap.2022.0404","relation":{},"ISSN":["1092-6429","1557-9034"],"issn-type":[{"value":"1092-6429","type":"print"},{"value":"1557-9034","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,1]]}}}