{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T06:55:26Z","timestamp":1782975326603,"version":"3.54.5"},"reference-count":29,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Laparoendoscopic &amp; Advanced Surgical Techniques"],"published-print":{"date-parts":[[2025,5,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Standard-of-care gastroesophageal reflux disease (GERD) procedures are associated with adverse events (AEs) (i.e., dysphagia, gas-bloating). RefluxStop has been developed to circumvent these outcomes. This study presents the results of 28 patients managed with RefluxStop in Germany.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Between July 2021 and November 2023, 28 patients with GERD underwent RefluxStop surgery, a novel laparoscopic antireflux procedure. Retrospective chart analysis with patient-informed consent was conducted to determine clinical outcomes, such as GERD Health-Related Quality of Life (GERD-HRQL) score, proton pump inhibitors (PPI) use, symptomatology, patient satisfaction, and perioperative AEs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Baseline characteristics (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 28): age 47 \u00b1 13.1 years; 67.9% female; body mass index (BMI) 27.3\u2009\u00b1\u20094.1 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ; 93% PPI use for 5.6\u2009\u00b1\u20092.7 years; and hiatal hernia in 100% of cases of mean (standard deviation [SD]) size 3.4 (0.8) cm, whereof 35.7% were large hiatal hernia (4\u20136 cm). At a mean (SD) follow-up of 14.1 (4.7) months, patients experienced 88.6% improvement in median (IQR) total GERD-HRQL score from a baseline of 35 (7.7) to 4 (4.2) at follow-up (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .05). Preoperative dysphagia (35.7%) resolved completely in all patients (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001). The mean (SD) GERD-HRQL heartburn subdomain decreased by 90.6% from a baseline of 18.1 (6.1) to 1.7 (1.2) at follow-up and all patients (100%) had scores &lt;5. Similarly, the mean (SD) regurgitation subdomain decreased from a baseline of 13.2 (4.7) to 2 (1.6) at follow-up and all patients (100%) had scores &lt;5. Patient satisfaction was achieved in 96.4% of patients with no PPI use required in 93% of patients (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001); only one patient required PPIs for persistent GERD symptoms. No cases of reoperation or esophageal dilatation were performed. Minor intraoperative AEs occurred in seven patients (i.e., neck emphysema).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>RefluxStop provides excellent safety and effectiveness outcomes for GERD treatment. Dysphagia completely resolved (0%) with 88.6% improvement in median GERD-HRQL score and satisfaction achieved in 96.4% of patients. These promising results reproduced the outcomes noted in the RefluxStop CE trial in real-world settings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/lap.2024.0390","type":"journal-article","created":{"date-parts":[[2025,3,28]],"date-time":"2025-03-28T11:28:57Z","timestamp":1743161337000},"page":"357-364","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Experience With an Innovative Surgical Treatment Option for Gastroesophageal Reflux Disease: Results of 28 Patients in a Retrospective Analysis"],"prefix":"10.1177","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4419-9018","authenticated-orcid":false,"given":"Moustafa","family":"Elshafei","sequence":"first","affiliation":[{"name":"Department of General, Visceral, and Minimally Invasive Surgery, Krankenhaus Nordwest, Frankfurt, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,5,2]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/SGA.0000000000000359"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.21037\/ales-20-26"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.1177\/26345161221126961"},{"key":"e_1_3_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(19)30408-X"},{"key":"e_1_3_6_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2006.02924.x"},{"key":"e_1_3_6_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2006.02763.x"},{"key":"e_1_3_6_8_2","doi-asserted-by":"publisher","DOI":"10.1186\/2047-783X-15-3-124"},{"key":"e_1_3_6_9_2","doi-asserted-by":"publisher","DOI":"10.1177\/21501319231207320"},{"key":"e_1_3_6_10_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.765061"},{"key":"e_1_3_6_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-016-3320-y"},{"key":"e_1_3_6_12_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-67202014000400006"},{"key":"e_1_3_6_13_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12893-020-00794-9"},{"key":"e_1_3_6_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-022-09463-9"},{"key":"e_1_3_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gassur.2005.10.003"},{"key":"e_1_3_6_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-012-2550-7"},{"key":"e_1_3_6_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12262-021-02973-1"},{"key":"e_1_3_6_18_2","doi-asserted-by":"publisher","DOI":"10.1177\/1756284819864549"},{"key":"e_1_3_6_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s15006-016-8303-0"},{"key":"e_1_3_6_20_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199203193261202"},{"key":"e_1_3_6_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-020-07792-1"},{"key":"e_1_3_6_22_2","doi-asserted-by":"publisher","DOI":"10.1093\/dote\/9.4.295"},{"key":"e_1_3_6_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-013-2803-0"},{"key":"e_1_3_6_24_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000217667.55939.64"},{"key":"e_1_3_6_25_2","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e31814a693e"},{"key":"e_1_3_6_26_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2019.0047"},{"key":"e_1_3_6_27_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.2010.81"},{"key":"e_1_3_6_28_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-019-04331-9"},{"key":"e_1_3_6_29_2","doi-asserted-by":"publisher","DOI":"10.1055\/a-1547-6599"},{"key":"e_1_3_6_30_2","article-title":"Laparoscopic anti-reflux operation: Fundoplication vs. Linx\u2014techniques and outcomes","volume":"5","author":"Sterbling HM","year":"2020","unstructured":"Sterbling HM, , Fernando HC. 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