{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T10:27:42Z","timestamp":1788431262075,"version":"build-2803163510"},"reference-count":22,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Laparoendoscopic &amp; Advanced Surgical Techniques"],"published-print":{"date-parts":[[2025,8,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>This study aimed to contribute to the ongoing debate regarding the optimal age to initiate colorectal cancer (CRC) screening by evaluating adenoma detection rates (ADRs) across different age and sex groups and to explore whether national screening guidelines should be revised in line with international trends.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      In this single-center, retrospective observational study, 1216 average-risk patients who underwent colonoscopy between January and December 2024 were analyzed. The patients were stratified into three age groups: Group 1 (40\u201344 years), Group 2 (45\u201349 years), and Group 3 (50\u201354 years). ADR, advanced neoplasia detection rate (ADNR), ADR by sex, Boston Bowel Preparation Scale (BBPS) score, and withdrawal times were evaluated. Patients with a history of polypectomy, family history of CRC, incomplete colonoscopy, or inadequate bowel preparation (BBPS score &lt;6) were excluded. Group comparisons were performed using Chi-square or Fisher\u2019s exact tests, with\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .05 considered statistically significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Overall ADR and ADNR were 20.8% and 2.6%, respectively. ADRs by group were 7.6%, 15.8%, and 18.9% in Groups 1, 2, and 3, respectively. A significant difference was found between Groups 1 and 2 (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .032) but not between Groups 2 and 3 (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .55). ADR was significantly higher in males (30.2%) than in females (13.1%;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001). ADNR was also higher in males (3.7%) than in females (1.8%;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .048). All patients had withdrawal times &gt;6 minutes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>ADR significantly increased from age 45, supporting the potential need to lower the CRC screening age and consider sex-specific strategies. Further prospective multicenter studies are warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/lap.2025.0071","type":"journal-article","created":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T04:05:32Z","timestamp":1746590732000},"page":"596-601","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Age and Sex Adenoma Detection Rates in Colonoscopy and Optimization of Screening Age: A Retrospective Analysis"],"prefix":"10.1177","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0079-2517","authenticated-orcid":false,"given":"Burak","family":"Sakar","sequence":"first","affiliation":[{"name":"Department of General Surgery, Antalya Training and Research Hospital, University of Health Sciences, Antalya, T\u00fcrkiye."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osman Zekai","family":"Oner","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Antalya Training and Research Hospital, University of Health Sciences, Antalya, T\u00fcrkiye."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Celik","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Antalya Training and Research Hospital, University of Health Sciences, Antalya, T\u00fcrkiye."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omer","family":"Celik","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Antalya Training and Research Hospital, University of Health Sciences, Antalya, T\u00fcrkiye."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Turan Can","family":"Y\u0131ld\u0131z","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Antalya Training and Research Hospital, University of Health Sciences, Antalya, T\u00fcrkiye."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ugur","family":"Dogan","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Antalya Training and Research Hospital, University of Health Sciences, Antalya, T\u00fcrkiye."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Onur Ilkay","family":"Dincer","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Antalya Training and Research Hospital, University of Health Sciences, Antalya, T\u00fcrkiye."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,8,13]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21262"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-024-12054-7"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.34622"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0000000000001953"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000001684"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.31742"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0000000000001301"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2009.05.032"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2008.05.057"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2011.12.012"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v25.i4.447"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0043-103411"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2022.1041915"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2024.57241"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa054967"},{"issue":"6","key":"e_1_3_5_17_2","first-page":"825","article-title":"Colonic neoplasia in asymptomatic persons with negative fecal occult blood tests: \u0130nfluence of age, gender, and family history","volume":"88","author":"Rex DK","year":"1993","unstructured":"Rex DK, , Lehman GA, , Ulbright TM, et al. 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