{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T12:07:34Z","timestamp":1779192454721,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lymphatic Research and Biology"],"published-print":{"date-parts":[[2017,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Aberrant, altered, or blocked lymphatic drainage may contribute to the high recurrence rate of breast cancer. Thus, an efficient evaluation of lymphatic drainage from the breasts and\/or upper limbs is essential in the management of lymphedema and in ipsilateral primary or contralateral recurrent breast cancer patients. There are very few reports of lymphatic drainage to the paravertebral lymph nodes in patients with a lymphedema after breast cancer surgery with or without reconstruction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We used lymphoscintigraphy to examine lymphatic drainage in a case series.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>We observed five patients with upper limb and\/or mammary lymphedema (after breast cancer surgery with or without reconstruction) who had lymphatic drainage from the upper limb or breast to the posterior intercostal and\/or paravertebral lymph nodes. One patient also presented with nodal relapse at the time of our investigation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The cases from this study demonstrate the unusual, and mostly unrecognized, lymphatic drainage pathways toward lymph nodes, which may be at risk for further evolution of breast cancer.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/lrb.2016.0037","type":"journal-article","created":{"date-parts":[[2017,3,21]],"date-time":"2017-03-21T16:57:25Z","timestamp":1490115445000},"page":"99-106","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Lymphatic Drainage to the Paravertebral Lymph Nodes in Breast Cancer Patients"],"prefix":"10.1177","volume":"15","author":[{"given":"Mirela Mariana","family":"Roman","sequence":"first","affiliation":[{"name":"Jules Bordet Institute","place":["Belgium"]},{"name":"Jules Bordet Institute","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Romain","family":"Barbieux","sequence":"additional","affiliation":[{"name":"Jules Bordet Institute","place":["Belgium"]},{"name":"Jules Bordet Institute","place":["Belgium"]},{"name":"Jules Bordet Institute","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivier","family":"Leduc","sequence":"additional","affiliation":[{"name":"Jules Bordet Institute","place":["Belgium"]},{"name":"HE PHSpaak","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Bourgeois","sequence":"additional","affiliation":[{"name":"Jules Bordet Institute","place":["Belgium"]},{"name":"Jules Bordet Institute","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,3,1]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19860915)58:6<1225::AID-CNCR2820580609>3.0.CO;2-#"},{"key":"e_1_3_2_3_2","first-page":"1258","article-title":"Altered lymphatic drainage after lymphadenectomy or radiotherapy of the axilla in patients with breast cancer","volume":"83","author":"Perre CI","year":"1996","unstructured":"Perre CI, , Hoefnagel CA, , Kroon BBR, , Zoetmulder FAN, , Rutgers EJT. Altered lymphatic drainage after lymphadenectomy or radiotherapy of the axilla in patients with breast cancer. Br J Surg, 1996; 83:1258.","journal-title":"Br J Surg"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-009-0452-2"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.4103\/0019-509X.12338"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2002.12.003"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1089\/154099903770948159"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-06-0168"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-008-9940-5"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.18.3517"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1089\/lrb.2013.0004"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000001128"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000001417"},{"key":"e_1_3_2_14_2","unstructured":"Bourgeois P. The postoperative investigations of the axilla and of the internal mammary chains in the management and prognosis of breast carcinomas. Th\u00e8se d'Agr\u00e9gation de l'Enseignement Sup\u00e9rieur Facult\u00e9 de M\u00e9decine Universit\u00e9 Libre de Bruxelles. Brussels Belgium; 1997."},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1089\/lrb.2013.0039"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1148\/131.1.205"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.137.4.847"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19850315)55:6<1403::AID-CNCR2820550640>3.0.CO;2-K"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-196603000-00020"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003072-199906000-00002"},{"key":"e_1_3_2_21_2","first-page":"178","article-title":"Significance of contralateral axillary metastases in carcinoma of the breast","volume":"12","author":"Devitt JE","year":"1969","unstructured":"Devitt JE, , Michalchuk AW. Significance of contralateral axillary metastases in carcinoma of the breast. Can J Surg, 1969; 12:178\u2013180.","journal-title":"Can J Surg"},{"key":"e_1_3_2_22_2","first-page":"713","article-title":"Contralateral axillary lymph node metastasis of cancer of the breast","volume":"85","author":"Daoud J","year":"1998","unstructured":"Daoud J, , Meziou M, , Kharrat M, , Sellami D, , Boudawara T, , Frikha M. Contralateral axillary lymph node metastasis of cancer of the breast. Bull Cancer, 1998; 85:713\u2013715.","journal-title":"Bull Cancer"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0104-11692009000500021"},{"key":"e_1_3_2_24_2","first-page":"38","article-title":"Lymphoscintigraphic assessment of manual lymphatic drainage. Report of 47 secondary lymphoedemas of the upper limb","volume":"6","author":"Ferrandez JC","year":"1997","unstructured":"Ferrandez JC, , Serin D, , Vinot JM. Lymphoscintigraphic assessment of manual lymphatic drainage. Report of 47 secondary lymphoedemas of the upper limb. Eur J Lymphol, 1997; 6:38\u201346.","journal-title":"Eur J Lymphol"}],"container-title":["Lymphatic Research and Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/lrb.2016.0037","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/lrb.2016.0037","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/lrb.2016.0037","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T11:35:31Z","timestamp":1779190531000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/lrb.2016.0037"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,1]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,3,1]]}},"alternative-id":["10.1089\/lrb.2016.0037"],"URL":"https:\/\/doi.org\/10.1089\/lrb.2016.0037","relation":{},"ISSN":["1539-6851","1557-8585"],"issn-type":[{"value":"1539-6851","type":"print"},{"value":"1557-8585","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,1]]}}}