{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T13:57:12Z","timestamp":1780667832303,"version":"3.54.1"},"reference-count":21,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lymphatic Research and Biology"],"published-print":{"date-parts":[[2020,4,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The L-Dex U400 is a recently developed measurement device to aid in the clinical assessment of unilateral lymphedema. Until now, little is known about variation in measurement results of the L-Dex U400. The aim of this study was to determine variation in measurement results in determining extracellular fluid of the arm with the L-Dex U400 under different measurement conditions on 2 days and to determine the reliability of these measurements in healthy subjects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results:<\/jats:title>\n                    <jats:p>Thirty participants were included. Participants were measured on 2 days, 2 weeks apart. Each day they were measured six times, 1st basic measurement, 2nd after a 10-minute rest period, 3rd second observer, 4th after drinking 200\u2009mL of coffee and rest for 30 minutes on the examination couch, 5th after 30 minutes of cycling on an exercise bike at 50 W and 50\u201360 rounds per minute, and 6th after a 10-minute rest period. The variance due to participants was 68% of the total variance and 32% was error variance. Lin's concordance coefficient (CCC), a reliability measure, ranged from 0.935 (first day, 1st and 2nd measurement of observer 1) to 0.517 (first and second day after a 10-minute rest period after cycling). In two CCCs, the lower limits of the 95% confidence interval were higher than 0.750. Repeatability coefficient was smallest for the basic observations on day 2 (4.6) and largest after cycling (8.0).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Clinical decision-making based on L-Dex U400 measurements should be regarded with caution because of moderate reliability.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/lrb.2018.0020","type":"journal-article","created":{"date-parts":[[2019,8,20]],"date-time":"2019-08-20T10:17:22Z","timestamp":1566296242000},"page":"110-115","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Variation in Measurement Results Using Bioimpedance Spectroscopy to Determine Extracellular Fluid of Upper Extremity"],"prefix":"10.1177","volume":"18","author":[{"given":"Carola Y.","family":"Timmer","sequence":"first","affiliation":[{"name":"Department of Rehabilitation Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joyce","family":"Bosman","sequence":"additional","affiliation":[{"name":"Physical Therapy Practice Lymfology and Oncology Physical therapy LOF, Groningen, The Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan H.B.","family":"Geertzen","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pieter U.","family":"Dijkstra","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands."},{"name":"Department of Oral and Maxillofacial Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,4,17]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2004.09.012"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-008-0090-6"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-008-0258-0"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clbc.2012.01.004"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-012-1433-8"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-015-3357-8"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2004.06.004"},{"key":"e_1_3_4_9_2","first-page":"1","article-title":"Correlation of L-Dex bioimpedance spectroscopy with limb volume and lymphatic function in lymphedema","volume":"00","author":"Coroneos CJ","year":"2018","unstructured":"Coroneos CJ, , Wong FC, , DeSnyder SM, , Shaitelman SF, , Schaverien MV. Correlation of L-Dex bioimpedance spectroscopy with limb volume and lymphatic function in lymphedema. Lymphat Res Biol, 2018; 00:1\u20137.","journal-title":"Lymphat Res Biol"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0899-9007(97)85179-9"},{"key":"e_1_3_4_11_2","first-page":"85","article-title":"NIH Public Access","volume":"46","author":"Fu MR","year":"2013","unstructured":"Fu MR, , Cleland CM, , Guth AA, , Kayal M, , Haber J, , Cartwright F, , Kleinman R, , Kang Y, , Scagliola JAD. NIH Public Access. Lymphology, 2013; 46:85\u201396.","journal-title":"Lymphology"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-015-0559-5"},{"key":"e_1_3_4_13_2","first-page":"273","article-title":"PAR-Q+ and ePARmed-X+: New risk stratification and physical activity clearance strategy for physicians and patients alike","volume":"59","author":"Bredin SSD","year":"2013","unstructured":"Bredin SSD, , Gledhill N, , Jamnik VK, , Warburton DER. PAR-Q+ and ePARmed-X+: New risk stratification and physical activity clearance strategy for physicians and patients alike. Can Fam Physician, 2013; 59:273\u2013277.","journal-title":"Can Fam Physician"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0197-2456(05)80019-4"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/1753-6405.12484"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0969-8043(97)00057-2"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1997.150"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.3109\/07357900902918494"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.10301"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1089\/lrb.2008.1027"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1258\/phleb.2010.010s08"},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2007.08.003"}],"container-title":["Lymphatic Research and Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/lrb.2018.0020","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/lrb.2018.0020","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/lrb.2018.0020","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:11:41Z","timestamp":1777666301000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/lrb.2018.0020"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,1]]},"references-count":21,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,4,1]]}},"alternative-id":["10.1089\/lrb.2018.0020"],"URL":"https:\/\/doi.org\/10.1089\/lrb.2018.0020","relation":{},"ISSN":["1539-6851","1557-8585"],"issn-type":[{"value":"1539-6851","type":"print"},{"value":"1557-8585","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4,1]]}}}