{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T05:43:22Z","timestamp":1790228602735,"version":"4.1.0"},"reference-count":38,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lymphatic Research and Biology"],"published-print":{"date-parts":[[2020,4,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>\n                      Local tissue water in patients with breast cancer-related lymphedema (BCRL) can be assessed by measurement of the tissue dielectric constant using the MoistureMeterD Compact\n                      <jats:sup>\u00ae<\/jats:sup>\n                      (MMDC) device, or by performing the pitting test. Although these assessment methods are commonly used in clinical practice, literature shows a lack of research on their clinimetric properties. Therefore, the aim of this study was to investigate reliability of both methods, in assessing the upper limb in BCRL.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results:<\/jats:title>\n                    <jats:p>Thirty women with BCRL were enrolled. Local tissue water was evaluated at nine reference points on the upper limb and trunk, using both methods. To determine intra- and inter-rater reliability of the MMDC device (using the absolute percentages of water content [PWC%] and interarm PWC% ratios based on single and multiple measures), intraclass correlation coefficients (ICCs), and standard errors of the measurement were calculated. To determine intra- and inter-rater agreement of the pitting test, Cohen's kappa coefficients were calculated as well as percentages of agreement. MMDC measurements yielded moderate to very strong intra- (ICC 0.648\u20130.947) and inter-rater (ICC 0.606\u20130.941) reliability, depending on the measurement location on the edematous limb. The pitting test showed a very strong intrarater agreement at nearly all defined points, but a weak inter-rater agreement, especially at the medial elbow and the breast.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This study supports the MMDC device and pitting test as being useful tools in the clinical evaluation of BCRL. However, further research into the concurrent validity of both tools is warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/lrb.2019.0013","type":"journal-article","created":{"date-parts":[[2019,7,22]],"date-time":"2019-07-22T14:00:01Z","timestamp":1563804001000},"page":"116-128","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":30,"title":["Reliability of the MoistureMeterD Compact Device and the Pitting Test to Evaluate Local Tissue Water in Subjects with Breast Cancer-Related Lymphedema"],"prefix":"10.1177","volume":"18","author":[{"given":"Tessa","family":"De Vrieze","sequence":"first","affiliation":[{"name":"Department of Rehabilitation Sciences, KU Leuven\u2013University of Leuven, Leuven, Belgium."},{"name":"Department of Rehabilitation Sciences and Physiotherapy, MOVANT, University of Antwerp, Antwerp, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nick","family":"Gebruers","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Sciences and Physiotherapy, MOVANT, University of Antwerp, Antwerp, Belgium."},{"name":"Multidisciplinary Oedema Clinic, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ines","family":"Nevelsteen","sequence":"additional","affiliation":[{"name":"Multidisciplinary Breast Centre, UZ Leuven\u2013University Hospitals Leuven, Leuven, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"An","family":"De Groef","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Sciences, KU Leuven\u2013University of Leuven, Leuven, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wiebren A.A.","family":"Tjalma","sequence":"additional","affiliation":[{"name":"Multidisciplinary Oedema Clinic, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium."},{"name":"Department of Medicine, MIPRO, University of Antwerp, Antwerp, Belgium."},{"name":"Multidisciplinary Breast Clinic, Antwerp University Hospital, Antwerp, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Thomis","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, Centre for Lymphoedema, UZ Leuven\u2013University Hospitals Leuven, Leuven, Belgium."},{"name":"Department of Physical Medicine and Rehabilitation, Center for Lymphoedema, UZ Leuven\u2013University Hospitals Leuven, Leuven, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lore","family":"Dams","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Sciences, KU Leuven\u2013University of Leuven, Leuven, Belgium."},{"name":"Department of Rehabilitation Sciences and Physiotherapy, MOVANT, University of Antwerp, Antwerp, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elien","family":"Van der Gucht","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Sciences, KU Leuven\u2013University of Leuven, Leuven, Belgium."},{"name":"Department of Rehabilitation Sciences and Physiotherapy, MOVANT, University of Antwerp, Antwerp, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frauke","family":"Penen","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Sciences, KU Leuven\u2013University of Leuven, Leuven, Belgium."},{"name":"Department of Rehabilitation Sciences and Physiotherapy, MOVANT, University of Antwerp, Antwerp, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nele","family":"Devoogdt","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Sciences, KU Leuven\u2013University of Leuven, Leuven, Belgium."},{"name":"Department of Vascular Surgery, Centre for Lymphoedema, UZ Leuven\u2013University Hospitals Leuven, Leuven, Belgium."},{"name":"Department of Physical Medicine and Rehabilitation, Center for Lymphoedema, UZ Leuven\u2013University Hospitals Leuven, Leuven, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,4,17]]},"reference":[{"key":"e_1_3_4_2_2","first-page":"1","article-title":"The diagnosis and treatment of peripheral lymphedema. 2013 Consensus Document of the International Society of Lymphology","volume":"46","author":"International Society of Lymphology","year":"2013","unstructured":"International Society of Lymphology. 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