{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T18:01:58Z","timestamp":1780509718877,"version":"3.54.1"},"reference-count":46,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2021,7,30]],"date-time":"2021-07-30T00:00:00Z","timestamp":1627603200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lymphatic Research and Biology"],"published-print":{"date-parts":[[2021,8,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The aim of this study was to compare the effects of complex decongestive therapy (CDT) accompanied by resistance exercises on extremity circumference, lymphedema volume, grip strength, functional status, and quality of life in the treatment of breast cancer-related lymphedema (BCRL) in patients with and without pain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results:<\/jats:title>\n                    <jats:p>\n                      Fifty patients with unilateral BCRL were divided into groups: with pain (Group 1,\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u200925) and without pain (Group 2,\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u200925). Thirty minutes of manual lymphatic drainage and multilayered short-stretch bandaging were applied to all patients five times a week for 4 weeks. In addition, all patients were informed about skin care and given a supervised resistance exercise program throughout the treatment. During the 1-month follow-up period, patients were asked to use low-tension elastic garments and to continue their home exercise program. Differences in upper extremity circumference and volume; grip strength; Quick Disabilities of the Arm, Shoulder, and Hand; and Functional Assessment of Cancer Therapy-Breast scores were evaluated at baseline, after treatment (week 4), and at 1-month follow-up. Moreover, the pain intensity of patients in Group 1 was measured using the visual analog scale (VAS). Patients in both Group 1 and Group 2 showed a statistical improvement in all outcome measures after treatment and at follow-up (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.05); however, no significant difference was observed between the groups (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&gt;\u20090.05). In Group 1, a statistically significant decrease was observed in the VAS score both at the end of treatment (\u22121.7\u2009\u00b1\u20090.9) and at 1-month follow-up (\u22123.5\u2009\u00b1\u20091.2) (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Combined CDT and resistance exercises appear to be effective in BCRL patients both with and without pain.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/lrb.2020.0099","type":"journal-article","created":{"date-parts":[[2021,1,15]],"date-time":"2021-01-15T13:09:11Z","timestamp":1610716151000},"page":"383-390","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Effectiveness of Combined Complex Decongestive Therapy and Resistance Exercises in the Treatment of Lymphedema Associated with Breast Cancer and the Effect of Pain on Treatment Response"],"prefix":"10.1177","volume":"19","author":[{"given":"Mustafa","family":"Corum","sequence":"first","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Istanbul Physical Medicine and Rehabilitation Training and Research Hospital, Istanbul, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ceyhun","family":"Basoglu","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Istanbul Aydin University, Istanbul, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merve Damla","family":"Korkmaz","sequence":"additional","affiliation":[{"name":"Physical Medicine and Rehabilitation Clinic, Istanbul Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa Aziz","family":"Yildirim","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Istanbul Physical Medicine and Rehabilitation Training and Research Hospital, Istanbul, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kadriye","family":"Ones","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Istanbul Physical Medicine and Rehabilitation Training and Research Hospital, Istanbul, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,7,30]]},"reference":[{"key":"e_1_3_3_2_2","first-page":"170","article-title":"The diagnosis and treatment of peripheral lymphedema: 2016 consensus document of the International Society of Lymphology","volume":"49","author":"Executive Committee","year":"2016","unstructured":"Executive Committee. The diagnosis and treatment of peripheral lymphedema: 2016 consensus document of the International Society of Lymphology. Lymphology, 2016; 49:170\u2013184.","journal-title":"Lymphology"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(13)70076-7"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4741.2012.01252.x"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0060164"},{"key":"e_1_3_3_6_2","first-page":"174550571875638","article-title":"The implications of women's activity limitations and role disruptions during breast cancer survivorship","volume":"14","author":"Keesing S","year":"2018","unstructured":"Keesing S, , Rosenwax L, , McNamara B. The implications of women's activity limitations and role disruptions during breast cancer survivorship. 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Post-breast cancer lymphedema: Incidence increases from 12 to 30 to 60 months. Lymphology, 2010; 43:118.","journal-title":"Lymphology"},{"key":"e_1_3_3_20_2","first-page":"80","article-title":"Effects of compression on lymphoedema during resistance exercise in women with breast cancer-related lymphoedema: A randomised, cross-over trial","volume":"48","author":"Singh B","year":"2015","unstructured":"Singh B, , Newton R, , Cormie P, et al. Effects of compression on lymphoedema during resistance exercise in women with breast cancer-related lymphoedema: A randomised, cross-over trial. 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