{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T02:24:59Z","timestamp":1792376699798,"version":"4.4.0"},"reference-count":26,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lymphatic Research and Biology"],"published-print":{"date-parts":[[2022,2,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>The aim of this study is to investigate the effect of complex decongestive physiotherapy (CDP) plus intermittent pneumatic compression (IPC) applications on upper extremity circumference and volume in patients with lipedema.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results:<\/jats:title>\n                    <jats:p>All participants included in the study were included in a treatment protocol consisting of CDP and IPC. The Perometer 400 NT was used in the measurement of upper extremity volume and circumference before and after treatment. The measurements were performed in four reference points. According to the Perometer results before and after CDP, statistically significant reduction was found in the circumference of 3 of the 4 points of measurements performed in each of the left and right upper extremities. When the volume assessments were compared, it was seen that statistically significant reduction was found in the volume of both limbs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>A treatment program consisting of CDP and IPC can be effective in reducing the circumference and volume of the arm in patients with upper extremity lipedema. So, CDP applications can help prevent the development of complications such as lipolymphedema, hypertension, and heart failure.<\/jats:p>\n                    <jats:p>\n                      Clinical Trial Registration number: NCT04643392\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/register.clinicaltrials.gov\/prs\/app\/action\/SelectProtocol?sid=S000AF9B&amp;selectaction=Edit&amp;uid=U00055NT&amp;ts=2&amp;cx=-3oevdw\">https:\/\/register.clinicaltrials.gov\/prs\/app\/action\/SelectProtocol?sid=S000AF9B&amp;selectaction=Edit&amp;uid=U00055NT&amp;ts=2&amp;cx=-3oevdw<\/jats:ext-link>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/lrb.2020.0128","type":"journal-article","created":{"date-parts":[[2021,4,2]],"date-time":"2021-04-02T17:48:50Z","timestamp":1617385730000},"page":"71-75","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Reducing Circumference and Volume in Upper Extremity Lipedema: The Role of Complex Decongestive Physiotherapy"],"prefix":"10.1177","volume":"20","author":[{"given":"Melek","family":"Volkan-Yazici","sequence":"first","affiliation":[{"name":"Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Yuksek Ihtisas University, Ankara, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murat","family":"Esmer","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Gazi University, Ankara, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,2,28]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09413.x"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/1358863X17739698"},{"key":"e_1_3_6_4_2","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/S0025-6196(25)37697-4","article-title":"Lipedema of the legs: A syndrome characterized by fat legs and orthostatic edema","volume":"34","author":"Allen E","year":"1940","unstructured":"Allen E, , Hines E: Lipedema of the legs: A syndrome characterized by fat legs and orthostatic edema. 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