{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T23:35:12Z","timestamp":1793144112274,"version":"4.5.0"},"reference-count":32,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lymphatic Research and Biology"],"published-print":{"date-parts":[[2022,4,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Upper limb lymphedema may be revealed after breast cancer and its treatment. Among different treatment approaches, intermittent pneumatic compression (IPC) therapy and low-level laser therapy (LLLT) are reported as effective modalities in the treatment of postmastectomy upper limb lymphedema (PML). The aim of the current study is to investigate the long-term effectiveness of combined IPC plus LLLT versus IPC therapy alone in patients with PML.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results:<\/jats:title>\n                    <jats:p>\n                      The patients were allocated into two groups in this single-blinded, controlled clinical trial. Group I received combined treatment with IPC plus LLLT (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u200921) and group II received only IPC (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u200921). IPC treatment was given 5 sessions per week for 4 weeks (20 sessions). LLLT was also performed 5 sessions per week for 4 weeks (20 sessions). Clinical evaluations were performed before and after the treatment at the 3, 6, and 12-month follow-up visits. According to within-group analysis, statistically significant improvements in the circumference difference (\n                      <jats:italic toggle=\"yes\">C<\/jats:italic>\n                      <jats:sub>diff<\/jats:sub>\n                      ) and grip strength were observed in both groups (for\n                      <jats:italic toggle=\"yes\">C<\/jats:italic>\n                      <jats:sub>diff<\/jats:sub>\n                      ,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.018 and\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.032, respectively; for grip strength,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.001 and\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.046, respectively). Visual analog scale values for arm pain and shoulder pain during motion were decreased only in group I.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Both interventions have positive effects on lymphedema, grip strength, and pain. Long-term effects of combined therapy, especially on pain, are slightly superior to the pneumatic compression alone.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/lrb.2020.0132","type":"journal-article","created":{"date-parts":[[2021,4,7]],"date-time":"2021-04-07T16:03:04Z","timestamp":1617811384000},"page":"175-184","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Long-Term Effectiveness of Combined Intermittent Pneumatic Compression Plus Low-Level Laser Therapy in Patients with Postmastectomy Lymphedema: A Randomized Controlled Trial"],"prefix":"10.1177","volume":"20","author":[{"given":"Erkan","family":"Kozanoglu","sequence":"first","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Cukurova University Faculty of Medicine, Adana, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neslihan","family":"Gokcen","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Cukurova University Faculty of Medicine, Adana, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sibel","family":"Basaran","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Cukurova University Faculty of Medicine, Adana, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Semra","family":"Paydas","sequence":"additional","affiliation":[{"name":"Division of Oncology, Department of Internal Medicine, Cukurova University Faculty of Medicine, Adana, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,4,20]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2016.06.024"},{"key":"e_1_3_4_3_2","first-page":"81","article-title":"Methods to improve rehabilitation of patients following breast cancer surgery: A review of systematic reviews","volume":"7","author":"Loh SY","year":"2015","unstructured":"Loh SY, , Musa AN. Methods to improve rehabilitation of patients following breast cancer surgery: A review of systematic reviews. Breast Cancer (Dove Med Press), 2015; 7:81\u201398.","journal-title":"Breast Cancer (Dove Med Press)"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2010.03.050"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/PHM.0000000000001017"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.5606\/tftrd.2017.779"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.5606\/tftrd.2019.3126"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/tbj.12710"},{"key":"e_1_3_4_9_2","first-page":"3805","article-title":"Combined decongestive therapy and reduction of pain and heaviness in patients with breast cancer-related lymphedema","volume":"27","author":"Mobarakeh ZS","year":"2019","unstructured":"Mobarakeh ZS, , Mokhtari-Hesari P, , Lotfi-Tokaldany M, , Montazeri A, , Heidari M, , Zekri F. Combined decongestive therapy and reduction of pain and heaviness in patients with breast cancer-related lymphedema. Support Care Cancer, 2019; 27:3805\u20133811.","journal-title":"Support Care Cancer"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1177\/0269215508096173"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdl182"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11641"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008259505511"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/0269215519888792"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22947"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-019-02798-1"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1188\/13.ONF.383-393"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/phpp.12284"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1089\/pho.2008.2330"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-010-0888-8"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-017-3852-x"},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-012-1240-y"},{"key":"e_1_3_4_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-016-2056-y"},{"key":"e_1_3_4_24_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-012-1546-0"},{"key":"e_1_3_4_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0363-5023(84)80146-X"},{"key":"e_1_3_4_26_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2003.034322"},{"key":"e_1_3_4_27_2","first-page":"74","article-title":"Treatment of chronic postmastectomy lymphedema with low level laser therapy: A 2.5 year follow-up","volume":"31","author":"Piller NB","year":"1998","unstructured":"Piller NB, , Thelander A. Treatment of chronic postmastectomy lymphedema with low level laser therapy: A 2.5 year follow-up. Lymphology, 1998; 31: 74\u201386.","journal-title":"Lymphology"},{"key":"e_1_3_4_28_2","doi-asserted-by":"publisher","DOI":"10.1089\/lrb.2018.0034"},{"key":"e_1_3_4_29_2","first-page":"56","article-title":"A randomized study comparing manual lymph drainage with sequential pneumatic compression for treatment of postoperative arm lymphedema","volume":"31","author":"Johansson K","year":"1998","unstructured":"Johansson K, , Lie E, , Ekdahl C, , Lindfeldt J. A randomized study comparing manual lymph drainage with sequential pneumatic compression for treatment of postoperative arm lymphedema. 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