{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T05:35:47Z","timestamp":1782279347550,"version":"3.54.5"},"reference-count":20,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lymphatic Research and Biology"],"published-print":{"date-parts":[[2023,2,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Breast cancer-related lymphedema (BCRL) is correlated with poor quality of life (QOL). The effects of the management of lymphedema on QOL remain controversial. We analyzed the changes in QOL and identified factors associated with its improvement to improve the care of patients with BCRL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results:<\/jats:title>\n                    <jats:p>A total of 194 patients with BCRL were recruited, and their medical records were reviewed regarding type of surgery, chemotherapy, and radiation. Patients completed the European Organization for Research and Treatment of Cancer Quality of Life Questionnaires, and the volume and circumference of lymphedema were measured. Significant improvements in physical, emotional, cognitive, social, and role functioning, and future perspective were observed after BCRL management. However, the change in the size of lymphedema was not correlated with the change in QOL parameters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The management of BCRL has a beneficial effect on QOL. However, changes in the size of lymphedema did not reflect changes in QOL. Therefore, a comprehensive approach for the management of BCRL beyond reducing the size of lymphedema is recommended to improve QOL.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/lrb.2021.0009","type":"journal-article","created":{"date-parts":[[2022,6,10]],"date-time":"2022-06-10T11:42:50Z","timestamp":1654861370000},"page":"28-33","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["What Should We Focus on When Managing Breast Cancer-Related Lymphedema to Improve Quality of Life?"],"prefix":"10.1177","volume":"21","author":[{"given":"Hyun Sung","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Jongno-Gu, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun Jeong","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Jongno-Gu, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwan Sik","family":"Seo","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Jongno-Gu, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,2,16]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1245\/ASO.2004.04.017"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2002.12.003"},{"key":"e_1_3_4_4_2","first-page":"94","article-title":"Upper extremity lymphedema secondary to breast cancer","volume":"16","author":"Kim KS","year":"1992","unstructured":"Kim KS, , Ko HYJ. Upper extremity lymphedema secondary to breast cancer. J Korean Acad Rehabil Med, 1992; 16:94\u2013100.","journal-title":"J Korean Acad Rehabil Med"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.5535\/arm.2012.36.2.240"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19931201)72:11<3248::AID-CNCR2820721119>3.0.CO;2-Z"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(99)00008-2"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.137.11.1253"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-005-0810-y"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.sap.0000257149.42922.7e"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/93.2.96"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1308\/003588403321661299"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-006-9297-6"},{"key":"e_1_3_4_14_2","first-page":"143","article-title":"Effect of complex decongestive therapy on edema and the quality of life in breast cancer patients with unilateral lymphedema","volume":"40","author":"Kim S","year":"2007","unstructured":"Kim S, , Yi CH, , Kwon OY: Effect of complex decongestive therapy on edema and the quality of life in breast cancer patients with unilateral lymphedema. Lymphology, 2007; 40:143\u2013151.","journal-title":"Lymphology"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/00002820-199506000-00004"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1018487411186"},{"key":"e_1_3_4_17_2","first-page":"46","article-title":"The effect of complete decongestive therapy on the quality of life of patients with peripheral lymphedema","volume":"35","author":"Weiss JM","year":"2002","unstructured":"Weiss JM, , Spray BJ: The effect of complete decongestive therapy on the quality of life of patients with peripheral lymphedema. Lymphology, 2002; 35:46\u201358.","journal-title":"Lymphology"},{"key":"e_1_3_4_18_2","unstructured":"Fayers PM Aaronson NK Bjordal K Groenvold M Curran D Bottomley A on behalf of the EORTC Quality of Life Group. The eortc QLQ-c30 scoring manual 3rd edition. European Organization for Research and Treatment of Cancer 2001. 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