{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T03:07:19Z","timestamp":1780110439764,"version":"3.54.0"},"reference-count":48,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lymphatic Research and Biology"],"published-print":{"date-parts":[[2021,10,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Chronic edema (CO) is a complex condition, arising from different factors, including immobility and obesity. Edema and obesity can have a significant impact on quality of life of patients and their families. Understanding how to manage edema in obese patients is an increasing challenge for both patients and clinicians. As effective treatment options are limited for this population, it is more cost-effective for patients to lose weight before starting treatment. When patients cannot maintain weight loss, one option is to have bariatric surgery.<\/jats:p>\n                    <jats:p>This study was part of LIMPRINT: Lymphedema IMpact and PRevalence INTernational, a study with the aim of identifying the prevalence and impact of CO in different countries and health care settings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Purpose:<\/jats:title>\n                    <jats:p>To evaluate the prevalence and impact of CO among patients in a United Kingdom bariatric surgical service.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results:<\/jats:title>\n                    <jats:p>The gold standard pitting test assessed the presence of edema. General (EuroQOL-5 Dimensions [EQ-5D], RAND 36-Item Short Form Health Survey, Version 1.0 [SF-36], Generalized Anxiety Disorder 7-Item Scale [GAD-7] and Patient Health Questionnaire\u20139 [PHQ-9]), and edema-specific (Lymphedema Quality of Life [LYMQOL]) quality-of-life questionnaires were used to evaluate impact of edema.<\/jats:p>\n                    <jats:p>The prevalence of edema was 52.1% (25 of 48 participants had edema), potentially linked to obesity, immobility, and medications. Most participants had International Society of Lymphology (ISL) Stage I edema. There were no statistically significant differences between the quality of life of participants with and without edema. However, comparing SF-36 results and normative population data indicated that quality of life was much lower than those in the normative population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>\n                      This study highlights the high prevalence of edema and low quality of life of this bariatric population.\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/ClinicalTrials.gov\">ClinicalTrials.gov<\/jats:ext-link>\n                      ID: NCT03154593.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/lrb.2021.0055","type":"journal-article","created":{"date-parts":[[2021,10,21]],"date-time":"2021-10-21T14:57:25Z","timestamp":1634828245000},"page":"431-441","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Prevalence and Impact of Chronic Edema in Bariatric Patients: A LIMPRINT Study"],"prefix":"10.1177","volume":"19","author":[{"given":"Amy","family":"Newman","sequence":"first","affiliation":[{"name":"University Hospitals of Derby and Burton NHS Foundation Trust, Royal Derby Hospital, Derby, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3004-2821","authenticated-orcid":false,"given":"Vaughan","family":"Keeley","sequence":"additional","affiliation":[{"name":"University Hospitals of Derby and Burton NHS Foundation Trust, Royal Derby Hospital, Derby, United Kingdom."},{"name":"School of Medicine, Royal Derby Hospital Centre, University of Nottingham, Derby, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorraine","family":"Pinnington","sequence":"additional","affiliation":[{"name":"School of Medicine, Royal Derby Hospital Centre, University of Nottingham, Derby, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carol","family":"Green","sequence":"additional","affiliation":[{"name":"University Hospitals of Derby and Burton NHS Foundation Trust, Royal Derby Hospital, Derby, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katie","family":"Riches","sequence":"additional","affiliation":[{"name":"University Hospitals of Derby and Burton NHS Foundation Trust, Royal Derby Hospital, Derby, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J.","family":"Franks","sequence":"additional","affiliation":[{"name":"Centre for Research and Implementation of Clinical Practice, London, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iskandar","family":"Idris","sequence":"additional","affiliation":[{"name":"University Hospitals of Derby and Burton NHS Foundation Trust, Royal Derby Hospital, Derby, United Kingdom."},{"name":"School of Medicine, Royal Derby Hospital Centre, University of Nottingham, Derby, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2436-0129","authenticated-orcid":false,"given":"Christine J.","family":"Moffatt","sequence":"additional","affiliation":[{"name":"Centre for Research and Implementation of Clinical Practice, London, United Kingdom."},{"name":"Copenhagen Wound Healing Centre, Department of Dermatology, Bispebjerg Hospital, Copenhagen, Denmark."},{"name":"Institute of Nursing and Midwifery Care Excellence, City Hospital, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,10,15]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcg126"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2013.22.11.623"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.19803"},{"key":"e_1_3_5_5_2","volume-title":"Best Practice for the Management of Lymphoedema. 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