{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T05:33:20Z","timestamp":1790141600644,"version":"4.0.1"},"reference-count":18,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lymphatic Research and Biology"],"published-print":{"date-parts":[[2021,10,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>To define the profile of patients presenting with chronic edema (CE) in three centers in Italy (Lymphoedema IMpact and PRevalence INTernational).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results:<\/jats:title>\n                    <jats:p>Data were collected in patients referred for CE between September 2016 and July 2017. A total of 1637 were recruited, 86.7% (1419) outpatients and 13.3% (218) inpatients with 80.6% (1319) female and mean age 54 years. Primary lymphedema occurred in 28.2% (461). In the 71.8% (1176) with secondary CE cancer occurred in 72% (846) and 28% (330) due to other causes. Data showed that 84.2% (226) had full upper body mobility, 15.5% (41) had limited mobility and 0.2% (2) had lost all mobility. Lower limb mobility status: 90.4% (1205) complete mobility, 8.4% (112) reduced mobility and 1.2% (21) wheelchair bound. Concurrent leg ulceration occurred in 32.9% (322) with 3.1% (51) having antibiotics. Treatment patterns varied with only 32.4% (530) receiving instructions in skin care, 61.2% (1002) multilayer compression and a further 67.8% (1110) compression garment with 17.6% (288) having sequential pressure therapy. Only 1.4% (23) had received psychological support. Out of the total 481\/1637 (29.4%) were not prescribed any treatment. Only 50.4% (825) had access to subsidized treatments within the National and Regional Health Care System, whereas 49.6% (81) had to pay themselves with only half (50.9%) having access to treatment centers that were near their home.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Results from this study and active lobbying have led to changes in reimbursement of care for primary and secondary lymphedema in Italy; this has led to a much more optimistic picture for those affected.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/lrb.2021.0062","type":"journal-article","created":{"date-parts":[[2021,10,21]],"date-time":"2021-10-21T14:57:25Z","timestamp":1634828245000},"page":"468-472","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["LIMPRINT in Italy"],"prefix":"10.1177","volume":"19","author":[{"given":"Marina","family":"Cestari","sequence":"first","affiliation":[{"name":"O.U. Territorial Rehabilitation, NHS Umbria 2, Terni, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandro","family":"Michelini","sequence":"additional","affiliation":[{"name":"San Giovanni Battista Hospital, Rome, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Ricci","sequence":"additional","affiliation":[{"name":"University Hospital Company, Hospitals Reunited, Ancona, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J.","family":"Franks","sequence":"additional","affiliation":[{"name":"Centre for Research and Implementation of Clinical Practice, London, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susie","family":"Murray","sequence":"additional","affiliation":[{"name":"Centre for Research and Implementation of Clinical Practice, London, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2436-0129","authenticated-orcid":false,"given":"Christine J.","family":"Moffatt","sequence":"additional","affiliation":[{"name":"Centre for Research and Implementation of Clinical Practice, London, United Kingdom."},{"name":"Institute of Nursing and Midwifery Care Excellence, City Hospital, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom."},{"name":"Copenhagen Wound Healing Centre, Department of Dermatology, Bispebjerg Hospital, Copenhagen, Denmark."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serena","family":"Michelini","sequence":"additional","affiliation":[{"name":"Unit of Physical Medicine and Rehabilitation, Sant'Andrea Hospital, \u201cSapienza,\u201d University 13 of Rome, Rome, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,10,15]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(13)70076-7"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1089\/lrb.2018.0085"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/cge.12173"},{"key":"e_1_3_3_5_2","volume-title":"Investing to Overcome the Global Impact of Neglected Tropical Diseases: Third WHO Report on Neglected Tropical Diseases, Vol. 3","author":"World Health Organization","year":"2015","unstructured":"World Health Organization. Investing to Overcome the Global Impact of Neglected Tropical Diseases: Third WHO Report on Neglected Tropical Diseases, Vol. 3. Geneva: World Health Organization; 2015."},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1089\/lrb.2018.0084"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-4801.2005.00066.x"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2009.18.10.44602"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcg126"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.7861\/clinmedicine.4-5-448"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12694"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-481X.2010.00657.x"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1089\/lrb.2018.0077"},{"key":"e_1_3_3_14_2","first-page":"135","article-title":"LIMPRINT","volume":"17","author":"Quere I","year":"2019","unstructured":"Quere I, , Mercier G, , Dring E, , Sykorova M, , Windrum P, , Murray S, , Franks P, , Keeley V, , Sugama J, , Moffatt CJ. LIMPRINT. Estimation of the prevalence of lymphedema\/chronic oedema in acute hospital in-patients Lymphat Res Biol, 2019; 17:135\u2013140.","journal-title":"Estimation of the prevalence of lymphedema\/chronic oedema in acute hospital in-patients Lymphat Res Biol"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1089\/lrb.2019.0021"},{"key":"e_1_3_3_16_2","first-page":"63","article-title":"A cross sectional study of elderly individuals with oedema and skin injuries in long term care facilities","volume":"39","author":"Sato A","year":"2015","unstructured":"Sato A, , Dai M, , Fujmoto Y, , Yusuf S, , Tsuchiya S, , Iuchi T, , Tabata K, , Yamashita A, , Nakatani T, , Sanada H, , Sugama J. A cross sectional study of elderly individuals with oedema and skin injuries in long term care facilities. J Tsuruma Health Sci Soc Kanasawa Univ, 2015; 39:63\u201373.","journal-title":"J Tsuruma Health Sci Soc Kanasawa Univ"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1089\/lrb.2018.0081"},{"key":"e_1_3_3_18_2","first-page":"27","volume":"46","author":"Stout NL","unstructured":"Stout NL, , Weiss R, , Feldman JL, , Stewart BR, , Armer JM, , Cormier JN, , Shih Y-CT. A systematic review of care delivery models and economic analyses in lymphedema: Health policy impact (2004\u20132011) Lymphology 2013; 46:27\u201341.","journal-title":"Lymphology"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jval.2016.03.677"}],"container-title":["Lymphatic Research and Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/lrb.2021.0062","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/lrb.2021.0062","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/lrb.2021.0062","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:14:11Z","timestamp":1777666451000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/lrb.2021.0062"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,1]]},"references-count":18,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,10,1]]}},"alternative-id":["10.1089\/lrb.2021.0062"],"URL":"https:\/\/doi.org\/10.1089\/lrb.2021.0062","relation":{},"ISSN":["1539-6851","1557-8585"],"issn-type":[{"value":"1539-6851","type":"print"},{"value":"1557-8585","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,1]]}}}