{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T22:28:16Z","timestamp":1790116096631,"version":"4.0.1"},"reference-count":34,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lymphatic Research and Biology"],"published-print":{"date-parts":[[2023,2,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>\n                      Breast cancer-related lymphedema (BCRL) after primary therapy is a common condition, causing physical and psychological distress. Decongestive lymphedema therapy (DLT) using multi-layered compression bandages is an effective treatment. We conducted a randomized controlled trial evaluating the use of a specific mobilizing bandage (Mobiderm\n                      <jats:sup>\u00ae<\/jats:sup>\n                      ) on lymphedema volume reduction during the intensive phase of DLT.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results:<\/jats:title>\n                    <jats:p>\n                      Fifty female BCRL patients were randomized to receive either conventional multi-layered bandages or mobilizing bandaging by using Mobiderm. Affected limb volume and excess volume were evaluated at baseline (D0) and after 15 days. The primary outcome was change in affected limb volume after adjustment for baseline. Symptom scores were evaluated by visual analogue scale (VAS); safety and tolerability were also assessed. Baseline characteristics were comparable. Affected limb volume reduction was observed in both study groups after 15 days: by 19.0% in the Mobiderm arm and 8.6% in controls (adjusted values). The between-group mean difference in adjusted volume reduction at day 15 was 256\u2009mL (95% confidence interval [CI], 92.5 to 421.3\u2009mL;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.003) favoring Mobiderm. Reductions in excess volume of 57.3% (Mobiderm) and 25.1% (controls) were observed (adjusted values); with between-group mean difference in adjusted excess volume of 220.2\u2009mL (95% CI, 69.3 to 371.3\u2009mL;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.006) favoring Mobiderm. Pain\/heaviness VAS scores fell significantly in both groups, with mean reductions of 1.84 (Mobiderm) versus 0.83 (control;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.001). Both regimens were well tolerated.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The use of Mobiderm in multilayer compression bandaging shows benefit in lymphedema reduction and in alleviating functional symptoms\/pain in patients with BRCL.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/lrb.2021.0104","type":"journal-article","created":{"date-parts":[[2022,6,8]],"date-time":"2022-06-08T16:58:30Z","timestamp":1654707510000},"page":"52-59","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Safety and Efficacy of a Mobiderm Compression Bandage During Intensive Phase of Decongestive Therapy in Patients with Breast Cancer-Related Lymphedema: A Randomized Controlled Trial"],"prefix":"10.1177","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1477-945X","authenticated-orcid":false,"given":"Anita","family":"Dhar","sequence":"first","affiliation":[{"name":"Department of Surgical Disciplines and All India Institute of Medical Sciences, New Delhi, India."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5855-8865","authenticated-orcid":false,"given":"Anurag","family":"Srivastava","sequence":"additional","affiliation":[{"name":"Department of Surgical Disciplines and All India Institute of Medical Sciences, New Delhi, India."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2147-3109","authenticated-orcid":false,"given":"Ravindra M.","family":"Pandey","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prasanna","family":"Shrestha","sequence":"additional","affiliation":[{"name":"THUASNE, Saint Etienne, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phanie","family":"Villet","sequence":"additional","affiliation":[{"name":"THUASNE, Saint Etienne, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5371-1330","authenticated-orcid":false,"given":"Arun Rekha","family":"Gogia","sequence":"additional","affiliation":[{"name":"Amla Mediquip, New Delhi, India."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,2,16]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12282-011-0283-4"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(13)70076-7"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.21037\/gs.2017.11.04"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2014.06.004"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s13193-011-0046-x"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12609-017-0237-8"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-013-2715-7"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-011-1089-9"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2015.61.5948"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/89.5.377"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.17.9291"},{"key":"e_1_3_5_13_2","first-page":"170","article-title":"The diagnosis and treatment of peripheral lymphedema: 2016 Consensus document of the International Society of Lymphology","volume":"49","author":"Executive Committee","year":"2016","unstructured":"Executive Committee. The diagnosis and treatment of peripheral lymphedema: 2016 Consensus document of the International Society of Lymphology. Lymphology, 2016; 49:170\u2013184.","journal-title":"Lymphology"},{"key":"e_1_3_5_14_2","unstructured":"International Lymphoedema Framework. Best practice for the management of lymphoedema. 2nd edition. Compression therapy: A position document on compression bandaging. London: MEP; 2012."},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmv.2014.05.004"},{"key":"e_1_3_5_16_2","unstructured":"MOBIDERM\u00ae: The unique anti-oedema solution. Product information sheet. https:\/\/uk.thuasne.com\/en\/all-productsproduct\/bandages-short-stretch-long-stretch-adhesive (accessed December18 2020)."},{"key":"e_1_3_5_17_2","first-page":"2455","article-title":"Interest of an auto-adjustable nighttime compression sleeve (MOBIDERM\u00ae Autofit) in maintenance phase of upper limb lymphedema: The MARILYN pilot RCT","volume":"25","author":"Mestre S","year":"2017","unstructured":"Mestre S, , Calais C, , Gaillard G, , Nou M, , Pasqualini M, , Ben Amor C, et al. Interest of an auto-adjustable nighttime compression sleeve (MOBIDERM\u00ae Autofit) in maintenance phase of upper limb lymphedema: The MARILYN pilot RCT. Support Care Cancer, 2017; 25:2455\u20132462.","journal-title":"Support Care Cancer"},{"key":"e_1_3_5_18_2","doi-asserted-by":"publisher","DOI":"10.1089\/lrb.2017.0026"},{"key":"e_1_3_5_19_2","first-page":"1061","article-title":"Clinical use of a night-time MOBIDERM garment as a treatment modality for breast cancer-related lymphedema: A retrospective longitudinal cohort study","volume":"4","author":"Toccafondi A","year":"2017","unstructured":"Toccafondi A, , Bonacchi A, , Miccinesi G, , Baroncelli TA, , Franchi G, , Ben Amor C, , Pasqualini M, , Muraca MG. Clinical use of a night-time MOBIDERM garment as a treatment modality for breast cancer-related lymphedema: A retrospective longitudinal cohort study. Ann Vasc Med Res, 2017; 4:1061.","journal-title":"Ann Vasc Med Res"},{"key":"e_1_3_5_20_2","doi-asserted-by":"publisher","DOI":"10.12968\/bjcn.2018.23.Sup4.S22"},{"key":"e_1_3_5_21_2","first-page":"126","article-title":"Episodic dermatolymphangioadenitis (DLA) in patients with lymphedema of the lower extremities before and after administration of benzathine penicillin: A preliminary study","volume":"29","author":"Olszewski WL","year":"1996","unstructured":"Olszewski WL. Episodic dermatolymphangioadenitis (DLA) in patients with lymphedema of the lower extremities before and after administration of benzathine penicillin: A preliminary study. 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Lymphology, 2005; 38:66\u201380.","journal-title":"Lymphology"},{"key":"e_1_3_5_23_2","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000000268"},{"key":"e_1_3_5_24_2","first-page":"527","article-title":"Dose finding for an optimal compression pressure to reduce chronic edema of the extremities","volume":"30","author":"Partsch H","year":"2011","unstructured":"Partsch H, , Damstra RJ, , Mosti G. Dose finding for an optimal compression pressure to reduce chronic edema of the extremities. 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