{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:16:48Z","timestamp":1777922208031,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lymphatic Research and Biology"],"published-print":{"date-parts":[[2023,4,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>This study aimed to investigate the possible relationship between breast cancer-related lymphedema and central obesity, which is known to be effective in metabolic syndrome and chronic inflammation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results:<\/jats:title>\n                    <jats:p>\n                      Thirty-six patients (18 lymphedemas, 18 control) enrolled in the study. There was no statistically significant difference in demographic data between the two groups except body mass index (BMI) distribution (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.008). Although 50% of the patients in the study group were obese, this rate was 5.6% in the control group. Although there was a significant difference between the study and control groups in terms of abdominal circumference measurement, there was no significant difference between total and abdominal fat amount and ratios. When BMI and abdominal circumference measurements were evaluated together to predict lymphedema, the area under the curve in abdominal circumference measurement was higher than BMI (0.715 vs. 0.659). In receiver operating characteristic curve analysis, 107 cm of abdominal circumference measurement was determined as cutoff value for lymphedema, with 55% sensitivity and 89% specificity (Youden index: 0.44).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Abdominal circumference measurement can be evaluated together with BMI in determining the risk of lymphedema.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/lrb.2022.0008","type":"journal-article","created":{"date-parts":[[2022,8,29]],"date-time":"2022-08-29T12:31:36Z","timestamp":1661776296000},"page":"130-134","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Evaluation of Abdominal Fat Ratio in Patients with Breast Cancer-Related Lymphedema: A Controlled Study"],"prefix":"10.1177","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2449-7010","authenticated-orcid":false,"given":"Cansu","family":"Nakipo\u011flu","sequence":"first","affiliation":[{"name":"Department of Physical Therapy and Rehabilitation, Health Science Faculty, Demiroglu Bilim University, Istanbul, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zeynep","family":"Erdo\u011fan \u0130yig\u00fcn","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy and Rehabilitation, Health Science Faculty, Demiroglu Bilim University, Istanbul, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tuba","family":"Kayan Tapan","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy and Rehabilitation, Health Science Faculty, Demiroglu Bilim University, Istanbul, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vahit","family":"\u00d6zmen","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy and Rehabilitation, Health Science Faculty, Demiroglu Bilim University, Istanbul, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00fcrsel Remzi","family":"Soybir","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy and Rehabilitation, Health Science Faculty, Demiroglu Bilim University, Istanbul, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet Serkan","family":"\u0130lg\u00fcn","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy and Rehabilitation, Health Science Faculty, Demiroglu Bilim University, Istanbul, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,4,20]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18010171"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1089\/lrb.2014.0014"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.41.8574"},{"key":"e_1_3_4_5_2","unstructured":"Gen\u00e7er H. Evaluation of Upper Extremity Lymphedema and Response to Lymphedema Treatment by Quantitative Lymphoscintigraphy in Patients Performing Sentinel Lymph Node Biopsy and\/or Axillary Dissection for Breast Cancer. Erciyes University Faculty of Medicine. Specialization Thesis in Medicine Kayseri 2014 (Advisor: Prof. Dr. Mustafa Kula)."},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-015-3353-z"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2017.09.018"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-48382-5_25"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-017-5960-x"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2017.09.006"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.12.004"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.2165\/00128071-200203070-00006"},{"key":"e_1_3_4_13_2","doi-asserted-by":"crossref","unstructured":"Zuther JE Norton S. Pathology. Lymphedema management: The comprehensive guide for practitioners. New York: Thieme 3rd ed. Nobel Medicine Bookstores: Istanbul; 2013; pp. 46\u2013122.","DOI":"10.1055\/b-0034-91077"},{"key":"e_1_3_4_14_2","doi-asserted-by":"crossref","unstructured":"Grandl G Wolfrum C. (2018 February). Hemostasis endothelial stress inflammation and the metabolic syndrome. In: Seminars in immunopathology (Vol. 40 No. 2 pp. 215\u2013224). Springer: Berlin Heidelberg; doi: 10.1007\/s00281-017-0666-5.","DOI":"10.1007\/s00281-017-0666-5"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.trsl.2019.04.001"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.624256"},{"key":"e_1_3_4_17_2","unstructured":"Breast Cancer\u2014Arm Volume Calculator. Available from: https:\/\/riskcalc.org\/BreastCancerArmLymphedemaArmVolume\/ [last accessed: June 14 2022]."},{"key":"e_1_3_4_18_2","unstructured":"https:\/\/www.tanita.com\/en\/bc-418\/ [Last accessed: June 14 2022]."},{"key":"e_1_3_4_19_2","first-page":"1","article-title":"Obesity Diagnosis and Treatment Guide","author":"Turkish Society of Endocrinology and Metabolism","year":"2019","unstructured":"Turkish Society of Endocrinology and Metabolism. Obesity Diagnosis and Treatment Guide. Turkish Society of Endocrinology and Metabolism: Ankara;, 2019; 1\u2013112.","journal-title":"Turkish Society of Endocrinology and Metabolism: Ankara;"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1089\/lrb.2019.0009"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1089\/lrb.2016.0045"},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000002258"},{"key":"e_1_3_4_23_2","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000000268"},{"key":"e_1_3_4_24_2","doi-asserted-by":"publisher","DOI":"10.1159\/000345459"},{"key":"e_1_3_4_25_2","doi-asserted-by":"publisher","DOI":"10.1089\/lrb.2017.0068"},{"key":"e_1_3_4_26_2","doi-asserted-by":"publisher","DOI":"10.3233\/BD-160215"}],"container-title":["Lymphatic Research and Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/lrb.2022.0008","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/lrb.2022.0008","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/lrb.2022.0008","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:14:34Z","timestamp":1777666474000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/lrb.2022.0008"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,1]]},"references-count":25,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,4,1]]}},"alternative-id":["10.1089\/lrb.2022.0008"],"URL":"https:\/\/doi.org\/10.1089\/lrb.2022.0008","relation":{},"ISSN":["1539-6851","1557-8585"],"issn-type":[{"value":"1539-6851","type":"print"},{"value":"1557-8585","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,1]]}}}