{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T05:08:50Z","timestamp":1791954530078,"version":"4.3.4"},"reference-count":31,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lymphatic Research and Biology"],"published-print":{"date-parts":[[2023,12,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Lymphaticovenular anastomosis (LVA) has recently become a mainstream surgical treatment for lymphedema and is a useful treatment option in addition to conservative therapies such as compression therapy, exercise therapy, and lymphatic drainage. We performed LVA with the goal of stopping compression therapy and report the effect of LVA on secondary lymphedema of the upper extremities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results:<\/jats:title>\n                    <jats:p>The participants were 20 patients with secondary lymphedema of the upper extremities categorized as stage 2 or 3 according to the International Society of Lymphology classification. We measured and compared the upper limb circumference at six locations before and 6 months after LVA. Significant decreases in circumference after surgery were observed at 8\u2009cm proximal to the elbow, the elbow joint, 5\u2009cm distal to the elbow, and the wrist joints, but not at 2\u2009cm distal to the axilla or the dorsum of the hand. At more than 6 months postoperatively, eight patients who had been wearing compression gloves were no longer required to wear them, and three patients who had been wearing both sleeves and gloves were no longer required to wear them.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>LVA is effective in the treatment of secondary lymphedema of the upper extremities, particularly in improving elbow circumference, and is one of the treatments that contributes significantly to the improvement of quality of life. For severe cases with limited range of motion of the elbow joint, LVA should be performed first. Based on these results, we present an algorithm for upper extremity lymphedema treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/lrb.2022.0096","type":"journal-article","created":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T11:50:32Z","timestamp":1685447432000},"page":"574-580","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Efficacy of Lymphaticovenular Anastomosis for Secondary Upper Extremity Lymphedema: Treatment Strategies with Effects of Compression Therapy Discontinuation and Site-Specific Evaluation of the Upper Extremity"],"prefix":"10.1177","volume":"21","author":[{"given":"Erika","family":"Hamada","sequence":"first","affiliation":[{"name":"Department of Plastic Surgery, Toyama Nishi General Hospital, Toyama, Japan."},{"name":"Department of Plastic and Reconstructive Surgery, Toyama University Hospital, Toyama, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Onoda","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Toyama University Hospital, Toyama, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshihiko","family":"Satake","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Toyama University Hospital, Toyama, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,12,22]]},"reference":[{"issue":"1","key":"e_1_3_5_2_2","first-page":"19","article-title":"A detailed examination of the characteristics and treatment in a series of 33 idiopathic lymphedema patients","volume":"33","author":"Onoda S","year":"2017","unstructured":"Onoda S, , Yamada K, , Matsumoto K, et al. A detailed examination of the characteristics and treatment in a series of 33 idiopathic lymphedema patients. J Reconstr Microsurg, 2017; 33(1):19\u201325; doi: 10.1055\/s-0036-1586257","journal-title":"J Reconstr Microsurg"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(13)70076-7"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/pon.3745"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-017-4180-1"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0036-1572538"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1599100"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.9588"},{"issue":"6","key":"e_1_3_5_9_2","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1016\/j.bjps.2020.02.022","article-title":"Lymphaticovenular anastomosis in elderly patients","volume":"73","author":"Onoda S","year":"2020","unstructured":"Onoda S, , Kinoshita M. Lymphaticovenular anastomosis in elderly patients. J Plast Reconstr Aesthet Surg, 2020; 73(6):1174\u20131205; doi: 10.1016\/j.bjps.2020.02.022","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1080\/2000656X.2021.1964980"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/micr.22204"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/micr.30514"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.21037\/gs.2020.03.41"},{"issue":"4","key":"e_1_3_5_14_2","first-page":"170","article-title":"The diagnosis and treatment of peripheral lymphedema: 2016 consensus document of the International Society of Lymphology","volume":"49","author":"Executive Committee","year":"2016","unstructured":"Executive Committee. The diagnosis and treatment of peripheral lymphedema: 2016 consensus document of the International Society of Lymphology. Acta Angiol, 2016; 49(4):170\u2013184.","journal-title":"Acta Angiol"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e31820cf5df"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1089\/lrb.2020.0120"},{"key":"e_1_3_5_17_2","doi-asserted-by":"publisher","DOI":"10.3400\/avd.ra.12.00080"},{"key":"e_1_3_5_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-196207000-00002"},{"key":"e_1_3_5_19_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-197006000-00003"},{"key":"e_1_3_5_20_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2003-40575"},{"key":"e_1_3_5_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-019-05450-2"},{"key":"e_1_3_5_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsv.2020.05.007"},{"key":"e_1_3_5_23_2","doi-asserted-by":"publisher","DOI":"10.1159\/000509672"},{"key":"e_1_3_5_24_2","doi-asserted-by":"publisher","DOI":"10.1089\/lrb.2017.0067"},{"issue":"1","key":"e_1_3_5_25_2","article-title":"Microsurgery for management of primary and secondary lymphedema","volume":"9","author":"Drobot A","year":"2021","unstructured":"Drobot A, , Bez M, , Abu Shakra I, et al. Microsurgery for management of primary and secondary lymphedema. 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