{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:17:15Z","timestamp":1777922235531,"version":"3.51.4"},"reference-count":47,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lymphatic Research and Biology"],"published-print":{"date-parts":[[2025,2,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The aim of this study was to investigate the validity and reliability and identify determinants of the 6-minute walk test (6MWT) in patients with lower limb lymphedema (LLL).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results:<\/jats:title>\n                    <jats:p>\n                      The study included 28 patients with LLL and 28 healthy subjects. To investigate the convergent validity and determinants of the 6MWT, patients were assessed using the following measurements: circumference measurement for lymphedema severity, hand-held dynamometry for muscle strength, time up and go for functional mobility, five-time sit-to-stand test for functional lower extremity strength, Lower Extremity Functional Scale for lower extremity functionality, Lymphedema Life Impact Scale for quality of life, and International Physical Activity Questionnaire-Short Form for physical activity level. The test\u2013retest reliability of the 6MWT was assessed using intraclass correlation coefficients (ICCs). 6MWT, a test\u2013retest reliability analysis was carried out with 28 patients within 3\u20137 days. The receiver operating characteristic (ROC) curve was employed to determine the cut-off point of 6MWT. The test\u2013retest reliability of 6MWT was detected as excellent (ICC [95%] 0.93 [0.87\u20130.97]). Significant correlations were found between the 6MWT health-related and disease-specific parameters, indicating sufficient convergent validity (\n                      <jats:italic toggle=\"yes\">r<\/jats:italic>\n                      \u2265 0.3). The ROC curve indicated a cut-off point of 504 meters (area under the curve [AUC] 0.712 [95%CI: 0.575\u20130.849]). Multiple linear regression analysis demonstrated that lymphedema severity, hip abduction muscle strength, and lower limb functionality were the predictors of 6MWT.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The 6MWT has been shown to be a reliable and valid tool for assessing the functional capacity of patients with LLL.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/lrb.2023.0056","type":"journal-article","created":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T11:13:15Z","timestamp":1734606795000},"page":"1-10","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Measurement Properties and Determinants of the 6-Minute Walk Test in Patients with Lower Limb Lymphedema"],"prefix":"10.1177","volume":"23","author":[{"given":"Ahmet Burak","family":"Cakir","sequence":"first","affiliation":[{"name":"Faculty of Physical Therapy and Rehabilitation, Graduate School of Health Sciences, Dokuz Eylul University, Izmir, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Didem","family":"Karadibak","sequence":"additional","affiliation":[{"name":"Department of Cardiopulmonary Physiotherapy-Rehabilitation, Faculty of Physical Therapy and Rehabilitation, Dokuz Eylul University, Izmir, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sukriye Cansu","family":"Gultekin","sequence":"additional","affiliation":[{"name":"Faculty of Physical Therapy and Rehabilitation, Graduate School of Health Sciences, Dokuz Eylul University, Izmir, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serap","family":"Acar","sequence":"additional","affiliation":[{"name":"Department of Cardiopulmonary Physiotherapy-Rehabilitation, Faculty of Physical Therapy and Rehabilitation, Dokuz Eylul University, Izmir, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pembe","family":"Keskinoglu","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, School of Medicine, Dokuz Eylul University, Izmir, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,2,11]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.2458\/lymph.4649"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-097X.2010.00969.x"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1635117"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2017.03.022"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/0269216314545803"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2883-6-4"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1089\/lrb.2015.0027"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2883-2-4"},{"issue":"11","key":"e_1_3_4_10_2","first-page":"3017","article-title":"Physical activity, daily walking, and lower limb lymphedema associate with physical function among uterine cancer survivors","volume":"22","author":"Brown JC","year":"2014","unstructured":"Brown JC, , Lin LL, , Segal S, et al. 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