{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T03:40:16Z","timestamp":1785814816320,"version":"3.56.0"},"reference-count":23,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lymphatic Research and Biology"],"published-print":{"date-parts":[[2025,4,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Lymphaticovenular anastomosis (LVA) is the first-line surgical treatment for lymphedema. The therapeutic effects of LVA, including edema reduction and cellulitis prevention, vary among patients. We examined cases of palliative LVA in patients with lymphedema who were in the terminal stage due to recurrence or distant metastasis of the primary disease, with a focus on the course and usefulness of palliative LVA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results:<\/jats:title>\n                    <jats:p>A total of 13 palliative LVAs were performed in 12 patients undergoing palliative treatment. LVA was performed without interfering with chemotherapy or radiation. Data on site and stage of edema, compression treatment status, number of anastomoses, percentage change in circumferential diameter (the total circumference at six locations was compared), treatment efficacy, and patient prognosis were collected. Edema was present in the upper and lower extremities of 10 and 2 patients, respectively. The average postoperative decrease in circumferential diameter was 8.6%. Psychological evaluation was based on the self-reports of patients, and 11 out of 12 patients showed improvement in their mental state. Two patients died during the observation period due to deterioration in the underlying disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>We reported our experience with palliative LVA in patients with advanced malignancies. Many patients had favorable physical and psychological outcomes. Surgery can be performed safely with appropriate planning based on the condition of the patients. Palliative LVA may be a treatment option for patients with recurrent or distant metastases of the primary disease who are refractory to edema treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/lrb.2024.0079","type":"journal-article","created":{"date-parts":[[2025,1,10]],"date-time":"2025-01-10T04:30:01Z","timestamp":1736483401000},"page":"71-77","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["The Concept of Palliative Lymphaticovenular Anastomosis"],"prefix":"10.1177","volume":"23","author":[{"given":"Kahori","family":"Tsukura","sequence":"first","affiliation":[{"name":"Department of Plastic and Reconstructive, Aesthetic Surgery, Toyama University Hospital, Toyama, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Onoda","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive, Aesthetic Surgery, Toyama University Hospital, Toyama, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshihiko","family":"Satake","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive, Aesthetic Surgery, Toyama University Hospital, Toyama, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika","family":"Hamada","sequence":"additional","affiliation":[{"name":"Department of Lymphedema Treatment Outpatient, Toyama Nishi General Hospital, Toyama, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,4,10]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3181e5f6a9"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2012.11.025"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/micr.1025"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000002254"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2023.06.068"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsv.2020.05.007"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000004628"},{"issue":"1","key":"e_1_3_3_9_2","first-page":"8","article-title":"Quality of life following liposuction and conservative treatment of arm lymphedema","volume":"39","author":"Brorson H","year":"2006","unstructured":"Brorson H, , Ohlin K, , Olsson G, et al. Quality of life following liposuction and conservative treatment of arm lymphedema. Lymphology, 2006; 39(1):8\u201325.","journal-title":"Lymphology"},{"issue":"6","key":"e_1_3_3_10_2","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1016\/j.bjps.2020.02.022","article-title":"Lymphaticovenular anastomosis in elderly patients","volume":"73","author":"Onoda S","year":"2020","unstructured":"Onoda S, , Kinoshita M. Lymphaticovenular anastomosis in elderly patients. J Plast Reconstr Aesthet Surg, 2020; 73(6):1174\u20131205.","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2021.08.012"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/micr.22204"},{"issue":"1","key":"e_1_3_3_13_2","first-page":"19","article-title":"A detailed examination of the characteristics and treatment in a series of 33 idiopathic lymphedema patients","volume":"33","author":"Onoda S","year":"2017","unstructured":"Onoda S, , Yamada K, , Matsumoto K, et al. A detailed examination of the characteristics and treatment in a series of 33 idiopathic lymphedema patients. J Reconstr Microsurg, 2017; 33(1):19\u201325.","journal-title":"J Reconstr Microsurg"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2019.04.023"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.12968\/ijpn.2009.15.10.44883"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyq093"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.12968\/ijpn.2017.23.3.111"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/GOX.0000000000005739"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23319"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2007.03.008"},{"issue":"3","key":"e_1_3_3_21_2","first-page":"CD011276","article-title":"Breast surgery for metastatic breast cancer","volume":"3","author":"Tosello G","year":"2018","unstructured":"Tosello G, , Torloni MR, , Mota BS, et al. Breast surgery for metastatic breast cancer. Cochrane Database Syst Rev, 2018; 3(3):CD011276.","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40792-023-01711-x"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.5999\/aps.2020.01704"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1649518"}],"container-title":["Lymphatic Research and Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/lrb.2024.0079","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/lrb.2024.0079","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/lrb.2024.0079","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:15:34Z","timestamp":1777666534000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/lrb.2024.0079"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,1]]},"references-count":23,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,4,1]]}},"alternative-id":["10.1089\/lrb.2024.0079"],"URL":"https:\/\/doi.org\/10.1089\/lrb.2024.0079","relation":{},"ISSN":["1539-6851","1557-8585"],"issn-type":[{"value":"1539-6851","type":"print"},{"value":"1557-8585","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,1]]}}}