{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T22:36:49Z","timestamp":1770763009363,"version":"3.50.0"},"reference-count":0,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[1997,12,1]],"date-time":"1997-12-01T00:00:00Z","timestamp":880934400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[1997,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    To investigate factors that could be involved in the emergence of antibiotic resistant\n                    <jats:italic toggle=\"yes\">S. typhi<\/jats:italic>\n                    , we characterized R plasmids and antibiotic resistant\n                    <jats:italic toggle=\"yes\">S. typhi<\/jats:italic>\n                    strains from two outbreaks of typhoid in Peru and Chile. Differences in the Inc HI1 plasmids of Peruvian and Chilean strains were identified by conjugation and incompatibility studies and plasmid DNA characterization. Antibiotic-resistant\n                    <jats:italic toggle=\"yes\">S. typhi<\/jats:italic>\n                    harboring Inc HI1 plasmids belonged to a reduced number of\n                    <jats:italic toggle=\"yes\">Pst<\/jats:italic>\n                    1 and\n                    <jats:italic toggle=\"yes\">Cla<\/jats:italic>\n                    1 ribotypes and IS\n                    <jats:italic toggle=\"yes\">200<\/jats:italic>\n                    types, in contrast to the high genetic diversity found among epidemic antibiotic-susceptible\n                    <jats:italic toggle=\"yes\">S. typhi<\/jats:italic>\n                    .\n                    <jats:sup>15<\/jats:sup>\n                    The low diversity of antibiotic-resistant\n                    <jats:italic toggle=\"yes\">S. typhi<\/jats:italic>\n                    suggests that they may express properties that are related to both their ability to harbor Inc HI1 R plasmids and to disseminate.\n                  <\/jats:p>","DOI":"10.1089\/mdr.1997.3.339","type":"journal-article","created":{"date-parts":[[2009,1,29]],"date-time":"2009-01-29T19:18:17Z","timestamp":1233256697000},"page":"339-343","source":"Crossref","is-referenced-by-count":11,"title":["Antibiotic-Resistant\n                    <i>Salmonella typhi<\/i>\n                    From Two Outbreaks: Few Ribotypes and IS\n                    <i>200<\/i>\n                    Types Harbor Inc HI1 Plasmids"],"prefix":"10.1177","volume":"3","author":[{"given":"Alberto","family":"Fica","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Elena","family":"Fernandez-Beros","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lieselotte","family":"Aron-Hott","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Rivas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karin","family":"D'OTTONE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge","family":"Chumpitaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose M.","family":"Guevara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Rodriguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felipe","family":"Cabello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1997,12]]},"container-title":["Microbial Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.1997.3.339","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.1997.3.339","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T18:12:51Z","timestamp":1770747171000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/mdr.1997.3.339"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,12]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1997,12]]}},"alternative-id":["10.1089\/mdr.1997.3.339"],"URL":"https:\/\/doi.org\/10.1089\/mdr.1997.3.339","relation":{},"ISSN":["1076-6294","1931-8448"],"issn-type":[{"value":"1076-6294","type":"print"},{"value":"1931-8448","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,12]]}}}