{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:22:08Z","timestamp":1777922528588,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2005,3,1]],"date-time":"2005-03-01T00:00:00Z","timestamp":1109635200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2005,3]]},"abstract":"<jats:p>\n                    Pulsed-field gel electrophoresis typing of 60 extended-spectrum \u03b2-lactamase-producing\n                    <jats:italic toggle=\"yes\">Klebsiella pneumoniae<\/jats:italic>\n                    (ESBL\n                    <jats:italic toggle=\"yes\">Kp<\/jats:italic>\n                    ) isolates obtained in a neonatal intensive care unit during an outbreak indicated the dissemination of two major bacterial genotypes associated with colonization and invasive disease: one composed by aminoglycoside-resistant isolates and the other by aminoglycoside-susceptible isolates. A urease-negative phenotype was observed among aminoglycoside-resistant ESBL\n                    <jats:italic toggle=\"yes\">Kp<\/jats:italic>\n                    . Six pairs of isolates from gastrointestinal (GI) colonization and isolates from invasive disease that occurred 3\u201323 days later were shown to belong to the same genotype, reinforcing a direct association between colonization and subsequent disease. These data indicate that screening for ESBL\n                    <jats:italic toggle=\"yes\">Kp<\/jats:italic>\n                    GI colonization in an outbreak setting may be useful to detect neonates at a higher risk of invasive disease.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2005.11.21","type":"journal-article","created":{"date-parts":[[2005,3,15]],"date-time":"2005-03-15T13:55:32Z","timestamp":1110894932000},"page":"21-25","source":"Crossref","is-referenced-by-count":8,"title":["Genetic Relatedness among Extended-Spectrum \u03b2-Lactamase-Producing\n                    <i>Klebsiella pneumoniae<\/i>\n                    Outbreak Isolates Associated with Colonization and Invasive Disease in a Neonatal Intensive Care Unit"],"prefix":"10.1177","volume":"11","author":[{"given":"Val\u00e9ria C\u00e2mara","family":"De Almeida","sequence":"first","affiliation":[{"name":"Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmem L\u00facia","family":"Pessoa-Silva","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge Luiz","family":"Mello Sampaio","sequence":"additional","affiliation":[{"name":"Fleury-Centro de Medicina Diagn\u00f3stica, S\u00e3o Paulo, S\u00e3o Paulo, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo Pinto Gontijo","family":"Filho","sequence":"additional","affiliation":[{"name":"Departamento de Microbiologia e Imunologia, Universidade Federal de Uberl\u00e2ndia, Minas Gerais, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00facia Martins","family":"Teixeira","sequence":"additional","affiliation":[{"name":"Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beatriz Meurer","family":"Moreira","sequence":"additional","affiliation":[{"name":"Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2005,3]]},"container-title":["Microbial Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2005.11.21","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2005.11.21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:23:03Z","timestamp":1777666983000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/mdr.2005.11.21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,3]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2005,3]]}},"alternative-id":["10.1089\/mdr.2005.11.21"],"URL":"https:\/\/doi.org\/10.1089\/mdr.2005.11.21","relation":{},"ISSN":["1076-6294","1931-8448"],"issn-type":[{"value":"1076-6294","type":"print"},{"value":"1931-8448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,3]]}}}