{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T02:10:53Z","timestamp":1784686253009,"version":"3.55.0"},"reference-count":0,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2005,12,1]],"date-time":"2005-12-01T00:00:00Z","timestamp":1133395200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2005,12]]},"abstract":"\n The presence and mechanism of acquired resistance to erythromycin, tylosin, lincomycin, quinupristin\/dalfopristin,\ntetracycline, chloramphenicol, gentamicin, kanamycin, and vancomycin were determined in 97 and\n104 enterococci isolated from rectal swabs of cats and dogs, respectively. Eleven feline and three canine enterococcal\nisolates contained the\n aac(6')-Ie-aph(2'')-Ia<\/jats:italic>\n gene encoding high-level resistance to gentamicin, an\nantibiotic often used for treating enterococcal infections in humans. The combination of\n erm<\/jats:italic>\n (B) and\n vat<\/jats:italic>\n (E)\ngenes encoding resistance to streptogramins was detected in one canine quinupristin\/dalfopristin-resistant\n Enterococcus\nfaecium<\/jats:italic>\n isolate. Four quinupristin\/dalfopristin-resistant enterococci only contained the\n erm<\/jats:italic>\n (B) gene.\nCross resistance against macrolides and lincosamides (30%) and resistance against tetracyclines (55%) was\nfound to be widely distributed among enterococci from pets. In all of the feline and in 93% of the canine\nmacrolide and lincosamide-resistant isolates, this resistance was encoded by the\n erm<\/jats:italic>\n (B) gene.\n tet<\/jats:italic>\n (M) was the\nmost prevalent tetracycline resistance gene. It was detected in 91% of the feline and 86% of the canine tetracycline-\nresistant enterococci. A high occurrence of the Tn\n 916<\/jats:italic>\n \/Tn\n 1545<\/jats:italic>\n transposon family was found among\nthese\n tet<\/jats:italic>\n (M)-positive isolates. Enterococci from pet animals with resistance against vancomycin were not found.\nThis study shows that enterococci from the intestinal microbiota of cats and dogs may act as a reservoir of\nresistance genes for animal or human pathogens.\n <\/jats:p>","DOI":"10.1089\/mdr.2005.11.395","type":"journal-article","created":{"date-parts":[[2005,12,16]],"date-time":"2005-12-16T10:12:03Z","timestamp":1134727923000},"page":"395-403","source":"Crossref","is-referenced-by-count":39,"title":["Presence and Mechanism of Antimicrobial Resistanceamong Enterococci from Cats and Dogs"],"prefix":"10.1177","volume":"11","author":[{"given":"Ellen De","family":"Leener","sequence":"first","affiliation":[{"name":"Department of Pathology, Bacteriology and Poultry Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820 Merelbeke, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annemie","family":"Decostere","sequence":"additional","affiliation":[{"name":"Department of Pathology, Bacteriology and Poultry Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820 Merelbeke, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelyn M.","family":"De Graef","sequence":"additional","affiliation":[{"name":"Department of Pathology, Bacteriology and Poultry Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820 Merelbeke, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hilde","family":"Moyaert","sequence":"additional","affiliation":[{"name":"Department of Pathology, Bacteriology and Poultry Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820 Merelbeke, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Freddy","family":"Haesebrouck","sequence":"additional","affiliation":[{"name":"Department of Pathology, Bacteriology and Poultry Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820 Merelbeke, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2005,12,16]]},"container-title":["Microbial Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2005.11.395","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2005.11.395","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:23:17Z","timestamp":1777666997000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/mdr.2005.11.395"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,12]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005,12]]}},"alternative-id":["10.1089\/mdr.2005.11.395"],"URL":"https:\/\/doi.org\/10.1089\/mdr.2005.11.395","relation":{},"ISSN":["1076-6294","1931-8448"],"issn-type":[{"value":"1076-6294","type":"print"},{"value":"1931-8448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,12]]}}}