{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:22:24Z","timestamp":1777922544628,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2006,3,1]],"date-time":"2006-03-01T00:00:00Z","timestamp":1141171200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2006,3]]},"abstract":"<jats:p>\n                    Antimicrobial resistance patterns and capsular groups of penicillin-resistant\n                    <jats:italic toggle=\"yes\">Streptococcus pneumoniae<\/jats:italic>\n                    (PRP;\nMIC penicillin G \u2265 0.5 mg\/ml) in Sweden between 1997 and 2003 were described, and trends in resistance\nand antibiotic sales during the same period were compared. The most common serogroups were in descending\norder 9, 19, 14, 23, and 6. Despite a low and stable annual PRP rate (proportion of PRP out of all pneumococci)\nof around 2% during the study period, the proportion of PRP resistant to other antibiotics increased.\nOf all tested PRP isolates, 82% were also resistant to trimethoprim\/sulfamethoxazole, 32% had additional resistance\nto tetracycline, and 26% to erythromycin. Antibiotic sales figures for all studied antibiotic subgroups\ndecreased during the same period. Little correlation was found between antibiotic sales and PRP resistance\nrates, indicating that there are still other poorly defined factors contributing to the reported resistance levels\nin the population. However, although PRP strains in Sweden are becoming more commonly resistant to antibiotics\nother than\n                    <jats:italic toggle=\"yes\">\u03b2<\/jats:italic>\n                    -lactams, the low and further reduced antibiotic sales still might have delayed the development\nand rapid spread of PRP in the population.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2006.12.16","type":"journal-article","created":{"date-parts":[[2006,4,3]],"date-time":"2006-04-03T10:49:08Z","timestamp":1144061348000},"page":"16-22","source":"Crossref","is-referenced-by-count":16,"title":["Penicillin-Resistant Pneumococci in Sweden 1997\u20132003: Increased Multiresistance Despite Stable Prevalence and Decreased Antibiotic Use"],"prefix":"10.1177","volume":"12","author":[{"given":"Liselotte","family":"H\u00f6gberg","sequence":"first","affiliation":[{"name":"Department of Epidemiology, Swedish Institute for Infectious Disease Control, Solna, Sweden."},{"name":"Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karl","family":"Ekdahl","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Swedish Institute for Infectious Disease Control, Solna, Sweden."},{"name":"Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karin","family":"Sj\u00f6str\u00f6m","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, Swedish Institute for Infectious Disease Control, Solna, Sweden."},{"name":"Microbiology and Tumour Biology Center, Karolinska Institutet, Solna, Sweden."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbro","family":"Olsson-Liljequist","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, Swedish Institute for Infectious Disease Control, Solna, Sweden."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mats","family":"Walder","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Malm\u00f6 University Hospital, Malm\u00f6, Sweden."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Melander","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Lund University Hospital, Lund, Sweden."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00e5kan","family":"Ringberg","sequence":"additional","affiliation":[{"name":"Regional Department of Communicable Disease Control in Sk\u00e5ne, Malm\u00f6, Sweden."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Birgitta Henriques","family":"Normark","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, Swedish Institute for Infectious Disease Control, Solna, Sweden."},{"name":"Microbiology and Tumour Biology Center, Karolinska Institutet, Solna, Sweden."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2006,3]]},"container-title":["Microbial Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2006.12.16","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2006.12.16","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:23:28Z","timestamp":1777667008000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/mdr.2006.12.16"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,3]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2006,3]]}},"alternative-id":["10.1089\/mdr.2006.12.16"],"URL":"https:\/\/doi.org\/10.1089\/mdr.2006.12.16","relation":{},"ISSN":["1076-6294","1931-8448"],"issn-type":[{"value":"1076-6294","type":"print"},{"value":"1931-8448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,3]]}}}