{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:22:26Z","timestamp":1777922546281,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2006,9,1]],"date-time":"2006-09-01T00:00:00Z","timestamp":1157068800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2006,9]]},"abstract":"<jats:p>\n                    The prevalence of extended-spectrum\n                    <jats:italic toggle=\"yes\">\u03b2<\/jats:italic>\n                    -lactamase (ESBL)-producing Enterobacteriaceae in a tertiary hospital\nin Taiwan was assessed over a 16-month period. A total of 125 nonrepetitive ESBL-producing isolates of\n                    <jats:italic toggle=\"yes\">Enterobacter cloacae, Escherichia coli,<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">Klebsiella pneumoniae<\/jats:italic>\n                    were available for investigation using molecular\nmethods. Four predominant intensive care units (ICUs) were identified, and SHV-12 (59%), CTX-M-\n3 (36%), and CTX-M-14 (14%) were the three most frequent ESBLs. SHV-12 was predominant among\n                    <jats:italic toggle=\"yes\">E.\ncloacae<\/jats:italic>\n                    in the burn unit and\n                    <jats:italic toggle=\"yes\">K. pneumoniae<\/jats:italic>\n                    in the other three chest medicine-related ICUs. CTX-M-3 was\npredominant among\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">K. pneumoniae<\/jats:italic>\n                    in three other ICUs. The dissemination of ESBL-producing\nEnterobacteriaceae in four ICUs of a medical center in Taiwan is a consequence of the clonal dissemination\nof a few epidemic strains along with the horizontal transmission of resistance genes-carrying plasmids among\nbacterial organisms.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2006.12.203","type":"journal-article","created":{"date-parts":[[2006,9,26]],"date-time":"2006-09-26T10:30:33Z","timestamp":1159266633000},"page":"203-209","source":"Crossref","is-referenced-by-count":8,"title":["Dissemination of Extended-Spectrum\n                    <i>\u03b2<\/i>\n                    -Lactamase-Producing Enterobacteriaceae in Intensive Care Units of a Medical Center in Taiwan"],"prefix":"10.1177","volume":"12","author":[{"given":"Tsu-Lan","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Clinical Pathology, Chang Gung Memorial Hospital, Taoyuan, Taiwan."},{"name":"Chang Gung University College of Medicine, Taoyuan, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ju-Hsin","family":"Chia","sequence":"additional","affiliation":[{"name":"Department of Clinical Pathology, Chang Gung Memorial Hospital, Taoyuan, Taiwan."},{"name":"Chang Gung University College of Medicine, Taoyuan, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin-Hui","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Clinical Pathology, Chang Gung Memorial Hospital, Taoyuan, Taiwan."},{"name":"Chang Gung University College of Medicine, Taoyuan, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chishih","family":"Chu","sequence":"additional","affiliation":[{"name":"Department of Applied Microbiology, National Chiayi University, Chiayi, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"An-Jing","family":"Kuo","sequence":"additional","affiliation":[{"name":"Department of Clinical Pathology, Chang Gung Memorial Hospital, Taoyuan, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheng-Hsun","family":"Chiu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Chang Gung Children's Hospital, Taoyuan, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2006,9]]},"container-title":["Microbial Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2006.12.203","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2006.12.203","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:23:32Z","timestamp":1777667012000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/mdr.2006.12.203"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,9]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2006,9]]}},"alternative-id":["10.1089\/mdr.2006.12.203"],"URL":"https:\/\/doi.org\/10.1089\/mdr.2006.12.203","relation":{},"ISSN":["1076-6294","1931-8448"],"issn-type":[{"value":"1076-6294","type":"print"},{"value":"1931-8448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,9]]}}}