{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:22:31Z","timestamp":1777922551082,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2006,12,1]],"date-time":"2006-12-01T00:00:00Z","timestamp":1164931200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2006,12]]},"abstract":"\n The present investigation was undertaken to assess the prevalence of extended-spectrum\n \u03b2<\/jats:italic>\n -lactamases\n(ES\n \u03b2<\/jats:italic>\n Ls) among urinary tract infection (UTI) isolates. During 4 months in 2004, a total of 650 Enterobacteriaceae\nstrains from UTIs was collected by five clinical microbiology laboratories located in southern Italy\nand the\n \u03b2<\/jats:italic>\n -lactamase production was investigated. A total of 50 of the 650 isolates were double-disk positive\nand suspected of producing an ES\n \u03b2<\/jats:italic>\n L;\n Escherichia coli<\/jats:italic>\n (36.0%) and\n Klebsiella pneumoniae<\/jats:italic>\n (32.0%) were the\nmost common species among all ES\n \u03b2<\/jats:italic>\n L producers. Characterization of ES\n \u03b2<\/jats:italic>\n L determinants was carried out\nby the colony blot hybridization method, and polymerase chain reaction (PCR) and DNA sequencing in order\nto identify the presence of\n bla<\/jats:italic>\n TEM<\/jats:sub>\n ,\n bla<\/jats:italic>\n SHV<\/jats:sub>\n ,\n bla<\/jats:italic>\n PER<\/jats:sub>\n , and\n bla<\/jats:italic>\n CTX-M<\/jats:sub>\n determinants. The ES\n \u03b2<\/jats:italic>\n L variants found\nin this study were the following: TEM-15, TEM-24, TEM-52, TEM-134, SHV-12, CTX-M-1, CTX-M-3, CTX-M-15, and PER-1. As expected, the majority of the isolates were found to be susceptible to imipenem (94%),\ncefepime (54%) and piperacillin-tazobactam (54%). The results of this survey show the prevalence of ES\n \u03b2<\/jats:italic>\n L\nenzymes among enterobacterial pathogens causing UTIs in southern Italy.\n <\/jats:p>","DOI":"10.1089\/mdr.2006.12.257","type":"journal-article","created":{"date-parts":[[2007,1,16]],"date-time":"2007-01-16T20:31:13Z","timestamp":1168979473000},"page":"257-264","source":"Crossref","is-referenced-by-count":14,"title":["Occurrence of Extended Spectrum\n \u03b2<\/i>\n -Lactamases Among Isolates of Enterobacteriaceae from Urinary Tract Infections in Southern Italy"],"prefix":"10.1177","volume":"12","author":[{"given":"Marisa","family":"Caccamo","sequence":"first","affiliation":[{"name":"Dipartimento di Scienze Microbiologiche, Universit\u00e0 di Catania, Catania, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariagrazia","family":"Perilli","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze e Tecnologie Biomediche, Universit\u00e0 dell'Aquila, L'Aquila, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Celenza","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze e Tecnologie Biomediche, Universit\u00e0 dell'Aquila, L'Aquila, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Bonfiglio","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze Microbiologiche, Universit\u00e0 di Catania, Catania, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianna","family":"Tempera","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze Microbiologiche, Universit\u00e0 di Catania, Catania, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianfranco","family":"Amicosante","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze e Tecnologie Biomediche, Universit\u00e0 dell'Aquila, L'Aquila, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2006,12]]},"container-title":["Microbial Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2006.12.257","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2006.12.257","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:23:36Z","timestamp":1777667016000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/mdr.2006.12.257"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,12]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2006,12]]}},"alternative-id":["10.1089\/mdr.2006.12.257"],"URL":"https:\/\/doi.org\/10.1089\/mdr.2006.12.257","relation":{},"ISSN":["1076-6294","1931-8448"],"issn-type":[{"value":"1076-6294","type":"print"},{"value":"1931-8448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,12]]}}}