{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:22:30Z","timestamp":1777922550353,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2006,3,1]],"date-time":"2006-03-01T00:00:00Z","timestamp":1141171200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2006,3]]},"abstract":"<jats:p>\n                    The aim of this study was to describe the frequency of antimicrobial-resistance and serotypes of nasopharyngeal\npneumococcal isolates from adolescents. Clinical data and nasopharyngeal specimens for culture were\ncollected from 1,013 adolescents as a part of a population-based study. A total of 83 isolates of\n                    <jats:italic toggle=\"yes\">Streptococcus\npneumoniae<\/jats:italic>\n                    were identified (8.2%). Seventy-four of the 83 isolates were serotyped. The median age of the 83\nadolescents colonized by pneumococci was 14 years (mean 14 \u00b1 2.2 yrs); 55.4% were males. Intermediate resistance\nto penicillin was detected in 7.2% (6\/83). No strain showed high resistance to penicillin. All isolates\nwere susceptible to clindamycin, chloramphenicol, rifampin, and vancomycin; 37.3%, 18.1%, and 4.8% were\nresistant to trimethoprim-sulfamethoxazole, tetracycline, and erythromycin, respectively. The most frequent\nserotypes (5\u201310% of strains each) were 6B, 6A, 23F, and 18C among 28 serotypes\/serogroups identified; 18.9%\nof the strains were nontypeable (NT). Intermediate resistance to penicillin was detected in serotypes 6B, 14,\nand NT. The rate of resistance to penicillin of nasopharyngeal isolates is low considering data from other studies\nabout invasive strains recovered from children in Brazil. Serotype patterns are similar, except for type 14,\nwhich was unusually infrequent.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2006.12.29","type":"journal-article","created":{"date-parts":[[2006,4,3]],"date-time":"2006-04-03T10:49:08Z","timestamp":1144061348000},"page":"29-32","source":"Crossref","is-referenced-by-count":4,"title":["Antimicrobial Resistance and Serotypes of Nasopharyngeal Strains of\n                    <i>Streptococcus pneumoniae<\/i>\n                    in Brazilian Adolescents"],"prefix":"10.1177","volume":"12","author":[{"given":"D\u00e9a Mascarenhas","family":"Cardozo","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Faculty of Medicine, Federal University of Bahia (UFBA), Salvador, Bahia, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristiana M.","family":"Nascimento-Carvalho","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Faculty of Medicine, Federal University of Bahia (UFBA), Salvador, Bahia, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Ang\u00e9lica","family":"Brand\u00e3o","sequence":"additional","affiliation":[{"name":"Central Laboratory of Bahia (LACEN), Salvador, Bahia, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gildete Maria Santos","family":"Azevedo","sequence":"additional","affiliation":[{"name":"Central Laboratory of Bahia (LACEN), Salvador, Bahia, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabiane Ribeiro","family":"De Souza","sequence":"additional","affiliation":[{"name":"Faculty of Biochemistry (UFBA), Salvador, Bahia, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N\u00edvea Maria Silveira","family":"Silva","sequence":"additional","affiliation":[{"name":"Faculty of Biochemistry (UFBA), Salvador, Bahia, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela Pires","family":"Brand\u00e3o","sequence":"additional","affiliation":[{"name":"Bacteriology Division, Adolfo Lutz Institute, S\u00e3o Paulo, Brazil."},{"name":"National Foundation of Health, S\u00e3o Paulo, Brazil."},{"name":"Oswaldo Cruz Foundation, Rio de Janeiro, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana L\u00facia","family":"Andrade","sequence":"additional","affiliation":[{"name":"Institute of Tropical Pathology and Public Health, Federal University of Goi\u00e1s, Goi\u00e2nia, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Cristina C.","family":"Brandileone","sequence":"additional","affiliation":[{"name":"Bacteriology Division, Adolfo Lutz Institute, S\u00e3o Paulo, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2006,3]]},"container-title":["Microbial Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2006.12.29","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2006.12.29","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:23:39Z","timestamp":1777667019000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/mdr.2006.12.29"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,3]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2006,3]]}},"alternative-id":["10.1089\/mdr.2006.12.29"],"URL":"https:\/\/doi.org\/10.1089\/mdr.2006.12.29","relation":{},"ISSN":["1076-6294","1931-8448"],"issn-type":[{"value":"1076-6294","type":"print"},{"value":"1931-8448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,3]]}}}