{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:23:00Z","timestamp":1777922580523,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T00:00:00Z","timestamp":1259625600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2009,12]]},"abstract":"\n Eighty-four isolates of\n Salmonella enterica<\/jats:italic>\n serovar Livingstone were collected from patients hospitalized in a pediatric ward in Sfax Hospital (South Tunisia). These isolates were responsible for two nosocomial outbreaks in 2000 and 2002. Twenty-eight clinical isolates of\n S. enterica<\/jats:italic>\n serovar Livingstone were also obtained in two other Tunisian hospitals in Monastir (Central Tunisia) and Tunis (North Tunisia), respectively, in 2002 and 2003. Pulsed-field gel electrophoresis yielded that these isolates were closely related. Antimicrobial susceptibility testing showed a particular \u03b2-lactam resistance phenotype, suggestive of the presence of an AmpC-type enzyme in 111 of the 112 clinical isolates.\n bla<\/jats:italic>\n ACC-1<\/jats:sub>\n was characterized by polymerase chain reaction (PCR) and sequence analysis in the 111 isolates. TEM-1 was characterized in all strains and SHV-2a in only two strains. The genetic organization of\n bla<\/jats:italic>\n ACC-1<\/jats:sub>\n was determined by PCR mapping and sequencing. The plasmid-borne\n bla<\/jats:italic>\n ACC-1<\/jats:sub>\n gene mapped immediately downstream from IS\n Ecp1<\/jats:italic>\n . This IS\n Ecp1<\/jats:italic>\n insertion sequence was itself disrupted by IS\n 26<\/jats:italic>\n insertion sequences. A supplementary deletion of 13\u2009bp was observed in IS\n Ecp1<\/jats:italic>\n upstream IS\n 26<\/jats:italic>\n , in all isolates from Tunis, except one. PCR analysis and sequencing also revealed the presence of\n tnpR<\/jats:italic>\n ,\n bla<\/jats:italic>\n SCO-1<\/jats:sub>\n ,\n gdha<\/jats:italic>\n , IS\n 1353<\/jats:italic>\n , and\n TniB\u03941<\/jats:italic>\n .\n <\/jats:p>","DOI":"10.1089\/mdr.2009.0035","type":"journal-article","created":{"date-parts":[[2009,10,26]],"date-time":"2009-10-26T13:06:58Z","timestamp":1256562418000},"page":"279-286","source":"Crossref","is-referenced-by-count":19,"title":["Molecular Epidemiology and Genetic Environment of Acquired\n bla<\/i>\n ACC-1<\/sub>\n in\n Salmonella enterica<\/i>\n Serotype Livingstone Causing a Large Nosocomial Outbreak in Tunisia"],"prefix":"10.1177","volume":"15","author":[{"given":"Sonia","family":"Ktari","sequence":"first","affiliation":[{"name":"University Hospital Center (CHU) of Habib Bourguiba","place":["Tunisia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillaume","family":"Arlet","sequence":"additional","affiliation":[{"name":"Tenon Hospital","place":["France"]},{"name":"Pierre and Marie Curie University-Paris","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte","family":"Verdet","sequence":"additional","affiliation":[{"name":"Tenon Hospital","place":["France"]},{"name":"Pierre and Marie Curie University-Paris","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samir","family":"Jaoua","sequence":"additional","affiliation":[{"name":"Center of Biotechnology","place":["Tunisia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amel","family":"Kachrid","sequence":"additional","affiliation":[{"name":"Children's Hospital","place":["Tunisia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saida","family":"Ben Redjeb","sequence":"additional","affiliation":[{"name":"CHU of Charles Nicolle","place":["Tunisia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fouzia","family":"Mahjoubi-Rhimi","sequence":"additional","affiliation":[{"name":"University Hospital Center (CHU) of Habib Bourguiba","place":["Tunisia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adnane","family":"Hammami","sequence":"additional","affiliation":[{"name":"University Hospital Center (CHU) of Habib Bourguiba","place":["Tunisia"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2009,12]]},"container-title":["Microbial Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2009.0035","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2009.0035","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:24:58Z","timestamp":1777667098000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/mdr.2009.0035"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,12]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["10.1089\/mdr.2009.0035"],"URL":"https:\/\/doi.org\/10.1089\/mdr.2009.0035","relation":{},"ISSN":["1076-6294","1931-8448"],"issn-type":[{"value":"1076-6294","type":"print"},{"value":"1931-8448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,12]]}}}