{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T22:02:41Z","timestamp":1791237761458,"version":"4.1.0"},"reference-count":0,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T00:00:00Z","timestamp":1259625600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2009,12]]},"abstract":"<jats:p>\n                    Recent studies from North America and Europe have demonstrated community-wide clonal spread of uropathogenic\n                    <jats:italic toggle=\"yes\">Escherichia coli<\/jats:italic>\n                    (UPEC). To investigate if a similar pattern of spread occurs in Brazil, we characterized UPEC from women with community-acquired urinary tract infection (UTI) in Rio de Janeiro.\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    isolates from women with UTI in one public outpatient clinic were evaluated for antibiotic susceptibility,\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    phylogenetic grouping, enterobacterial repetitive intergenic consensus (ERIC) 2 PCR and pulsed-field gel electrophoresis fingerprinting, and multilocus sequence typing. From March 2005 to November 2006, 344 patients were studied. Of these, 186 (54%) had confirmed UTI, 118 (63.4%) of which were caused by\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    . More than 50% of these isolates were resistant to ampicillin and trimethoprim\/sulfamethoxazole. Of these, 96 (81%) belonged to 19 ERIC2 clonal groups. The largest group included 15 isolates, all belonging to multilocus sequence typing group ST69 and phylogenetic group D; they had pulsed-field gel electrophoresis patterns sharing at least 89% similarity compared with the CgA reference strain ATCC BAA-457. CgA strains have been found to be widespread in the United States in the early 2000s. Clonal group\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    strains accounted for a large proportion (52%) of all UTIs and 82% of the trimethoprim\/sulfamethoxazole-resistant\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    UTIs. Thus, as in North America and Europe, UPECs that cause UTI in Rio de Janeiro also show clonal distribution, and a substantial proportion of drug-resistant UTI is caused by a small set of genetically related\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    strains.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2009.0067","type":"journal-article","created":{"date-parts":[[2009,10,26]],"date-time":"2009-10-26T13:06:58Z","timestamp":1256562418000},"page":"303-308","source":"Crossref","is-referenced-by-count":38,"title":["Clonal Composition of\n                    <i>Escherichia coli<\/i>\n                    Causing Community-Acquired Urinary Tract Infections in the State of Rio de Janeiro, Brazil"],"prefix":"10.1177","volume":"15","author":[{"given":"Rubens C.S.","family":"Dias","sequence":"first","affiliation":[{"name":"Federal University of Rio de Janeiro","place":["Brazil"]},{"name":"University of California"},{"name":"Federal University of Rio de Janeiro","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise V.","family":"Marangoni","sequence":"additional","affiliation":[{"name":"Federal University of Rio de Janeiro","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sherry P.","family":"Smith","sequence":"additional","affiliation":[{"name":"University of California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth M.","family":"Alves","sequence":"additional","affiliation":[{"name":"Federal University of Rio de Janeiro","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavia L.P.C.","family":"Pellegrino","sequence":"additional","affiliation":[{"name":"Federal University of Rio de Janeiro","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lee W.","family":"Riley","sequence":"additional","affiliation":[{"name":"University of California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz M.","family":"Moreira","sequence":"additional","affiliation":[{"name":"Federal University of Rio de Janeiro","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2009,12]]},"container-title":["Microbial Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2009.0067","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2009.0067","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:25:03Z","timestamp":1777667103000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/mdr.2009.0067"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,12]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["10.1089\/mdr.2009.0067"],"URL":"https:\/\/doi.org\/10.1089\/mdr.2009.0067","relation":{},"ISSN":["1076-6294","1931-8448"],"issn-type":[{"value":"1076-6294","type":"print"},{"value":"1931-8448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,12]]}}}