{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:23:13Z","timestamp":1777922593928,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2009,3,1]],"date-time":"2009-03-01T00:00:00Z","timestamp":1235865600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2009,3]]},"abstract":"<jats:p>\n                    The occurrence of antimicrobial resistance in\n                    <jats:italic toggle=\"yes\">Staphylococcus pseudintermedius<\/jats:italic>\n                    from skin and ear infections in a representative sample of dogs unexposed to antimicrobial treatment before sampling was examined. The obtained isolates were further examined for genetic polymorphism and genetic background of resistance. A total of 59 isolates of\n                    <jats:italic toggle=\"yes\">S. pseudintermedius<\/jats:italic>\n                    originating from 96 samples of 91 dogs in five different regions in Norway were included in this study. Susceptibility testing was performed using a broth dilution method. Resistant isolates were subjected to polymerase chain reaction for detection of resistance genes. All isolates were subjected to pulsed-field gel electrophoresis to examine the genetic polymorphism. In total, 19% of the isolates were susceptible to all antimicrobial agents included. Resistance to penicillin was most prevalent (70%), followed by resistance to fusidic acid (49%) and oxytetracycline (42%). Resistance to quinolones or cephalosporins was not observed. Resistance to penicillin, tetracycline, and erythromycin was mediated by the\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    Z \u03b2-lactamase gene, the\n                    <jats:italic toggle=\"yes\">tet<\/jats:italic>\n                    M gene, and the\n                    <jats:italic toggle=\"yes\">erm<\/jats:italic>\n                    B gene, respectively. One of the fusidic acid\u2013resistant isolates harbored a\n                    <jats:italic toggle=\"yes\">fus<\/jats:italic>\n                    C gene, whereas the mechanisms involved in resistance in the other fusidic acid\u2013resistant isolates remained unknown. Pulsed-field gel electrophoresis showed a high genetic polymorphism of\n                    <jats:italic toggle=\"yes\">S. pseudintermedius<\/jats:italic>\n                    . This study indicates that the occurrence of antimicrobial resistance is common among\n                    <jats:italic toggle=\"yes\">S. pseudintermedius<\/jats:italic>\n                    from dogs unexposed to antimicrobial treatment before sampling, and that there is a high genetic polymorphism among\n                    <jats:italic toggle=\"yes\">S. pseudintermedius.<\/jats:italic>\n                  <\/jats:p>","DOI":"10.1089\/mdr.2009.0865","type":"journal-article","created":{"date-parts":[[2009,2,13]],"date-time":"2009-02-13T09:58:07Z","timestamp":1234519087000},"page":"55-59","source":"Crossref","is-referenced-by-count":22,"title":["Antimicrobial Resistance in\n                    <i>Staphylococcus pseudintermedius<\/i>\n                    in the Norwegian Dog Population"],"prefix":"10.1177","volume":"15","author":[{"given":"Madelaine","family":"Norstr\u00f6m","sequence":"first","affiliation":[{"name":"National Veterinary Institute","place":["Norway"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marianne","family":"Sunde","sequence":"additional","affiliation":[{"name":"National Veterinary Institute","place":["Norway"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanne","family":"Tharaldsen","sequence":"additional","affiliation":[{"name":"National Veterinary Institute","place":["Norway"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tormod","family":"M\u00f8rk","sequence":"additional","affiliation":[{"name":"National Veterinary Institute","place":["Norway"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bjarne","family":"Bergsj\u00f8","sequence":"additional","affiliation":[{"name":"National Veterinary Institute","place":["Norway"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hilde","family":"Kruse","sequence":"additional","affiliation":[{"name":"National Veterinary Institute","place":["Norway"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2009,3]]},"container-title":["Microbial Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2009.0865","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2009.0865","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:25:18Z","timestamp":1777667118000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/mdr.2009.0865"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,3]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,3]]}},"alternative-id":["10.1089\/mdr.2009.0865"],"URL":"https:\/\/doi.org\/10.1089\/mdr.2009.0865","relation":{},"ISSN":["1076-6294","1931-8448"],"issn-type":[{"value":"1076-6294","type":"print"},{"value":"1931-8448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,3]]}}}