{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:23:30Z","timestamp":1777922610932,"version":"3.51.4"},"reference-count":43,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2010,9,1]],"date-time":"2010-09-01T00:00:00Z","timestamp":1283299200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2010,9]]},"abstract":"<jats:p>\n                    We evaluated the antimicrobial resistance patterns and molecular characteristics of 11 extraintestinal\n                    <jats:italic toggle=\"yes\">Escherichia coli<\/jats:italic>\n                    strains and 1 intestinal\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    from human infections collected in Brazil. Two\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    strains were nonsusceptible to extended spectrum cephalosporins (cefotaxime, ceftazidime, and cefepime); one isolated from diarrhea carried\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>CTX-M-14<\/jats:sub>\n                    and\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>TEM-1<\/jats:sub>\n                    , whereas the other, isolated from tracheal secretion, carried\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>CTX-M-15<\/jats:sub>\n                    and\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>OXA-1<\/jats:sub>\n                    . Five\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    strains showed resistance to quinolones. Integrase associated with class 1 integron (\n                    <jats:italic toggle=\"yes\">intl<\/jats:italic>\n                    1) was detected in 8 of the 12\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    strains belonging to various serotypes and this gene was carried by plasmids showing similar size. Pulsed-field gel electrophoresis showed that\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    strains were genetically diverse, and phylogenetic grouping showed that the\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    strains belonged to groups A, B2, and D (33.3%), respectively. This is the first report of\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    isolates carrying\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>CTX-M-14<\/jats:sub>\n                    and\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>CTX-M-15<\/jats:sub>\n                    in Brazil. The presence of mobile elements containing antimicrobial resistance genes is worrisome since it could promote the dissemination of resistance and lead to the acquisition of resistance to other antimicrobials agents such as the carbapenems.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2010.0008","type":"journal-article","created":{"date-parts":[[2010,8,12]],"date-time":"2010-08-12T23:01:19Z","timestamp":1281654079000},"page":"177-184","source":"Crossref","is-referenced-by-count":25,"title":["First Description of\n                    <i>bla<\/i>\n                    <sub>CTX-M-14<\/sub>\n                    - and\n                    <i>bla<\/i>\n                    <sub>CTX-M-15<\/sub>\n                    -Producing\n                    <i>Escherichia coli<\/i>\n                    Isolates in Brazil"],"prefix":"10.1177","volume":"16","author":[{"given":"Maria Cecilia","family":"Cergole-Novella","sequence":"first","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo","place":["Brazil"]},{"name":"Universidade Federal de S\u00e3o Paulo","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beatriz E.C.","family":"Guth","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariana","family":"Castanheira","sequence":"additional","affiliation":[{"name":"JMI Laboratories"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirian S.","family":"Carmo","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio C.C.","family":"Pignatari","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2010,9]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2003.09.001"},{"key":"e_1_3_3_3_2","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S1369-5274(99)00005-3","article-title":"The biological cost of antibiotic resistance","volume":"2","author":"Andersson D.I.","year":"1999","unstructured":"Andersson D.I., , Levin B.R. 1999. The biological cost of antibiotic resistance. Curr. Opin. Microbiol., 2:489\u2013493.","journal-title":"Curr. Opin. Microbiol."},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/7.6.1513"},{"key":"e_1_3_3_5_2","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1054\/drup.2000.0147","article-title":"The cost of antibiotic resistance from a bacterial perspective","volume":"3","author":"Bj\u00f6rkman J.","year":"2000","unstructured":"Bj\u00f6rkman J., , Andersson D.I. 2000. The cost of antibiotic resistance from a bacterial perspective. Drug Resist. Updat., 3:237\u2013245.","journal-title":"Drug Resist. 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