{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:23:26Z","timestamp":1777922606031,"version":"3.51.4"},"reference-count":32,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2010,9,1]],"date-time":"2010-09-01T00:00:00Z","timestamp":1283299200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2010,9]]},"abstract":"<jats:p>\n                    Community-acquired methicillin-resistant\n                    <jats:italic toggle=\"yes\">Staphylococcus aureus<\/jats:italic>\n                    (CA-MRSA) is becoming increasingly common worldwide. The purpose of this study was to identify the prevalence and molecular characteristics of MRSA bloodstream isolates in hospitals. Clinical data from patients with MRSA bacteremia between 2003 and 2005 were collected. Isolates were classified as hospital-acquired (HA-MRSA), health care-associated (HCA-MRSA), or CA-MRSA according to the time of isolation and the risk factors for colonization. Available strains were tested for the presence of\n                    <jats:italic toggle=\"yes\">mec<\/jats:italic>\n                    A, staphylococcal cassette chromosome\n                    <jats:italic toggle=\"yes\">mec<\/jats:italic>\n                    (SCC\n                    <jats:italic toggle=\"yes\">mec<\/jats:italic>\n                    ), and by multilocus sequence test. Among 129 cases, 78 nonduplicated isolates were analyzed. The proportion of CA-MRSA, HCA-MRSA, and HA-MRSA was 2.6% (2), 23.1% (18), and 74.4% (58), respectively. According to multilocus sequence test and SCC\n                    <jats:italic toggle=\"yes\">mec<\/jats:italic>\n                    , there were seven genotypes with sequence types (STs) and SCC\n                    <jats:italic toggle=\"yes\">mec<\/jats:italic>\n                    types. The predominant genotype, ST5-MRSA-II, was found in 57.7% (45). All type IVA isolates was ST72 (9), and ST72-MRSA-IVA was identified in CA-MRSA (2, 100%), HCA-MRSA (1, 5.6%), and HA-MRSA (6, 10.3%), respectively. In summary, CA-MRSA bacteremia was not common in our hospital during the period.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2010.0010","type":"journal-article","created":{"date-parts":[[2010,8,24]],"date-time":"2010-08-24T08:49:25Z","timestamp":1282639765000},"page":"217-222","source":"Crossref","is-referenced-by-count":10,"title":["Molecular Characteristics of Methicillin-Resistant\n                    <i>Staphylococcus aureus<\/i>\n                    Blood Isolates: Clonal Spread of Staphylococcal Cassette Chromosome\n                    <i>mec<\/i>\n                    Type IVA Between the Community and the Hospital"],"prefix":"10.1177","volume":"16","author":[{"given":"Soo-Youn","family":"Moon","sequence":"first","affiliation":[{"name":"Kyung Hee University Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hee-Joo","family":"Lee","sequence":"additional","affiliation":[{"name":"Kyung Hee University Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mi Suk","family":"Lee","sequence":"additional","affiliation":[{"name":"Kyung Hee University Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2010,9]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)08713-5"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.101.6.1644"},{"key":"e_1_3_3_4_2","doi-asserted-by":"crossref","first-page":"3610","DOI":"10.1128\/JCM.43.8.3610-3614.2005","article-title":"Prevalence of the ST239 clone of methicillin-resistant Staphylococcus aureus and differences in antimicrobial susceptibilities of ST239 and ST5 clones identified in a Korean hospital","volume":"43","author":"Cha H.Y.","year":"2005","unstructured":"Cha H.Y., , Moon D.C., , Choi C.H., , Oh J.Y., , Jeong Y.S., , Lee Y.C., , Seol S.Y., , Cho D.T., , Chang H.H., , Kim S.W., , Lee J.C. 2005. Prevalence of the ST239 clone of methicillin-resistant Staphylococcus aureus and differences in antimicrobial susceptibilities of ST239 and ST5 clones identified in a Korean hospital. J. Clin. Microbiol., 43:3610\u20133614.","journal-title":"J. Clin. Microbiol."},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid0702.010204"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00698-07"},{"key":"e_1_3_3_7_2","unstructured":"Clinical Laboratory Standards Institute. 2009. Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically. Approved Standard M07-A8 8th. Wayne PA."},{"key":"e_1_3_3_8_2","doi-asserted-by":"crossref","first-page":"9865","DOI":"10.1073\/pnas.161272898","article-title":"The evolution of methicillin resistance in Staphylococcus aureus: similarity of genetic backgrounds in historically early methicillin-susceptible and -resistant isolates and contemporary epidemic clones","volume":"98","author":"Crisostomo M.I.","year":"2001","unstructured":"Crisostomo M.I., , Westh H., , Tomasz A., , Chung M., , Oliveira D.C., , de Lencastre H. 2001. The evolution of methicillin resistance in Staphylococcus aureus: similarity of genetic backgrounds in historically early methicillin-susceptible and -resistant isolates and contemporary epidemic clones. Proc. Natl. Acad. Sci. U.S.A., 98:9865\u20139870.","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.38.3.1008-1015.2000"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.186.5.1518-1530.2004"},{"key":"e_1_3_3_11_2","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1128\/AAC.47.1.196-203.2003","article-title":"Comparative molecular analysis of community- or hospital-acquired methicillin-resistant Staphylococcus aureus. Antimicrob","volume":"47","author":"Fey P.D.","year":"2003","unstructured":"Fey P.D., , Said-Salim B., , Rupp M.E., , Hinrichs S.H., , Boxrud D.J., , Davis C.C., , Kreiswirth B.N., , Schlievert P.M. 2003. Comparative molecular analysis of community- or hospital-acquired methicillin-resistant Staphylococcus aureus. Antimicrob. Agents Chemother., 47:196\u2013203.","journal-title":"Agents Chemother."},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-137-10-200211190-00007"},{"key":"e_1_3_3_13_2","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1128\/jcm.30.3.577-580.1992","article-title":"Rapid method for epidemiological evaluation of gram-positive cocci by field inversion gel electrophoresis","volume":"30","author":"Goering R.V.","year":"1992","unstructured":"Goering R.V., , Winters M.A. 1992. Rapid method for epidemiological evaluation of gram-positive cocci by field inversion gel electrophoresis. J. Clin. Microbiol., 30:577\u2013580.","journal-title":"J. Clin. Microbiol."},{"key":"e_1_3_3_14_2","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1111\/j.1348-0421.1995.tb02239.x","article-title":"Molecular evolution of MRSA","volume":"39","author":"Hiramatsu K.","year":"1995","unstructured":"Hiramatsu K. 1995. Molecular evolution of MRSA. Microbiol. Immunol., 39:531\u2013543.","journal-title":"Microbiol. Immunol."},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00579-09"},{"key":"e_1_3_3_16_2","doi-asserted-by":"crossref","first-page":"2279","DOI":"10.1128\/JCM.41.6.2279-2281.2003","article-title":"Nationwide surveillance for Staphylococcus aureus with reduced susceptibility to vancomycin in Korea","volume":"41","author":"Kim H.B.","year":"2003","unstructured":"Kim H.B., , Park W.B., , Lee K.D., , Choi Y.J., , Park S.W., , Oh M.D., , Kim E.C., , Choe K.W. 2003. Nationwide surveillance for Staphylococcus aureus with reduced susceptibility to vancomycin in Korea. J. Clin. Microbiol., 41:2279\u20132281.","journal-title":"J. Clin. Microbiol."},{"key":"e_1_3_3_17_2","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.diagmicrobio.2006.05.003","article-title":"Association between the methicillin resistance of clinical isolates of Staphylococcus aureus, their staphylococcal cassette chromosome mec (SCCmec) subtype classification, and their toxin gene profiles","volume":"56","author":"Kim J.S.","year":"2006","unstructured":"Kim J.S., , Song W., , Kim H.S., , Cho H.C., , Lee K.M., , Choi M.S., , Kim E.C. 2006. Association between the methicillin resistance of clinical isolates of Staphylococcus aureus, their staphylococcal cassette chromosome mec (SCCmec) subtype classification, and their toxin gene profiles. Diagn. Microbiol. Infect. Dis., 56:289\u2013295.","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"e_1_3_3_18_2","doi-asserted-by":"crossref","first-page":"3583","DOI":"10.1128\/AAC.49.8.3583-3585.2005","article-title":"Genotypic diversity of methicillin-resistant Staphylococcus aureus isolates in Korean hospitals","volume":"49","author":"Ko K.S.","year":"2005","unstructured":"Ko K.S., , Kim Y.S., , Song J.H., , Yeom J.S., , Lee H., , Jung S.I., , Jeong D.R., , Kim S.W., , Chang H.H., , Ki H.K., , Moon C., , Oh W.S., , Peck K.R., , Lee N.Y. 2005. Genotypic diversity of methicillin-resistant Staphylococcus aureus isolates in Korean hospitals. Antimicrob. Agents Chemother., 49:3583\u20133585.","journal-title":"Antimicrob. Agents Chemother."},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.1.421-426.2005"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1086\/313461"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.46.4.1147-1152.2002"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00275-07"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1086\/323459"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.290.22.2976"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.11.4289-4294.2002"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.46.7.2155-2161.2002"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1089\/10766290152773365"},{"key":"e_1_3_3_28_2","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/S1473-3099(02)00227-X","article-title":"Secrets of success of a human pathogen: molecular evolution of pandemic clones of meticillin-resistant Staphylococcus aureus","volume":"2","author":"Oliveira D.C.","year":"2002","unstructured":"Oliveira D.C., , Tomasz A., , de Lencastre H. 2002. Secrets of success of a human pathogen: molecular evolution of pandemic clones of meticillin-resistant Staphylococcus aureus. Lancet Infect. Dis., 2:180\u2013189.","journal-title":"Lancet Infect. Dis."},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01147-07"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.47.12.3926-3934.2003"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1086\/502231"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1086\/313650"},{"key":"e_1_3_3_33_2","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1093\/jac\/dkh107","article-title":"Methicillin-resistant Staphylococcus aureus bacteraemia diagnosed at hospital admission: distinguishing between community-acquired versus health care-associated strains","volume":"53","author":"Tacconelli E.","year":"2004","unstructured":"Tacconelli E., , Venkataraman L., , De Girolami P.C., , EM D.A. 2004. Methicillin-resistant Staphylococcus aureus bacteraemia diagnosed at hospital admission: distinguishing between community-acquired versus health care-associated strains. J. Antimicrob. Chemother., 53:474\u2013479.","journal-title":"J. Antimicrob. Chemother."}],"container-title":["Microbial Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/mdr.2010.0010","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2010.0010","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2010.0010","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:25:35Z","timestamp":1777667135000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/mdr.2010.0010"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,9]]},"references-count":32,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010,9]]}},"alternative-id":["10.1089\/mdr.2010.0010"],"URL":"https:\/\/doi.org\/10.1089\/mdr.2010.0010","relation":{},"ISSN":["1076-6294","1931-8448"],"issn-type":[{"value":"1076-6294","type":"print"},{"value":"1931-8448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,9]]}}}