{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T01:31:02Z","timestamp":1790472662177,"version":"4.1.0"},"reference-count":9,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2011,3,1]],"date-time":"2011-03-01T00:00:00Z","timestamp":1298937600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2011,3]]},"abstract":"<jats:p>\n                    The aim of this assay was to develop an experimental model of digestive colonization of chickens with bacteria harboring\n                    <jats:italic toggle=\"yes\">qnr,<\/jats:italic>\n                    extended-spectrum beta-lactamase, or\n                    <jats:italic toggle=\"yes\">ampC<\/jats:italic>\n                    genes. Specific pathogen-free chickens were orally inoculated with two\n                    <jats:italic toggle=\"yes\">Escherichia coli<\/jats:italic>\n                    strains containing either the plasmid pMG252 bearing\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>FOX<\/jats:sub>\n                    and\n                    <jats:italic toggle=\"yes\">qnrA<\/jats:italic>\n                    genes, or pMG298 bearing\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>CTX-M<\/jats:sub>\n                    and\n                    <jats:italic toggle=\"yes\">qnrB<\/jats:italic>\n                    genes. Analysis of strains isolated from fecal samples showed that the two strains were able to persist for several weeks in the digestive flora of inoculated birds and could rapidly spread to noninoculated ones. However, the multi-resistant isolates were maintained as a small proportion of the overall enterobacterial population. The\n                    <jats:italic toggle=\"yes\">qnr<\/jats:italic>\n                    , extended-spectrum beta-lactamase, and\n                    <jats:italic toggle=\"yes\">ampC<\/jats:italic>\n                    resistance genes could be transferred,\n                    <jats:italic toggle=\"yes\">in vivo,<\/jats:italic>\n                    in the absence of selective pressure, to other chicken\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    or\n                    <jats:italic toggle=\"yes\">Klebsiella pneumoniae<\/jats:italic>\n                    isolates.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2010.0096","type":"journal-article","created":{"date-parts":[[2010,12,29]],"date-time":"2010-12-29T18:45:04Z","timestamp":1293648304000},"page":"129-134","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":18,"title":["Persistence and Spread of\n                    <i>qnr<\/i>\n                    , Extended-Spectrum Beta-Lactamase, and\n                    <i>ampC<\/i>\n                    Resistance Genes in the Digestive Tract of Chickens"],"prefix":"10.1177","volume":"17","author":[{"given":"Laetitia","family":"Le Devendec","sequence":"first","affiliation":[{"name":"Unit\u00e9 Mycoplasmologie Bact\u00e9riologie","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axelle","family":"Bouder","sequence":"additional","affiliation":[{"name":"Unit\u00e9 Mycoplasmologie Bact\u00e9riologie","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Dheilly","sequence":"additional","affiliation":[{"name":"Unit\u00e9 Mycoplasmologie Bact\u00e9riologie","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gwena\u00eblle","family":"Hellard","sequence":"additional","affiliation":[{"name":"Unit\u00e9 Mycoplasmologie Bact\u00e9riologie","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Kempf","sequence":"additional","affiliation":[{"name":"Unit\u00e9 Mycoplasmologie Bact\u00e9riologie","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2011,3]]},"reference":[{"key":"e_1_3_3_2_2","unstructured":"CASFM. 2008. Recommandations 2008 du comit\u00e9 del'antibiogramme de la soci\u00e9t\u00e9 fran\u00e7aise de microbiologie. http:\/\/sfm.asso.fr. 2010November19th."},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.2174\/092986709787581879"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkm204"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00239-09"},{"key":"e_1_3_3_6_2","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1126\/science.3538420","article-title":"Separation of large DNA molecules by contour-clamped homogeneous electric fields","volume":"234","author":"Chu G.","year":"1986","unstructured":"Chu G., , Vollrath D., , Davis R.W. 1986. Separation of large DNA molecules by contour-clamped homogeneous electric fields. Science, 234:1582\u20131585.","journal-title":"Science"},{"key":"e_1_3_3_7_2","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1099\/ijs.0.02408-0","article-title":"Recognition of two genetic groups in the Klebsiella oxytoca taxon on the basis of chromosomal \u00ce\u00b2-lactamase and housekeeping gene sequences as well as ERIC-1R PCR typing","volume":"53","author":"Granier S.A.","year":"2003","unstructured":"Granier S.A., , Plaisance L., , Leflon-Guibout V., , Lagier E., , Morand S., , Goldstein F.W., , Nicolas-Chanoine M.H. 2003. Recognition of two genetic groups in the Klebsiella oxytoca taxon on the basis of chromosomal \u00ce\u00b2-lactamase and housekeeping gene sequences as well as ERIC-1R PCR typing. Int. J. Syst. Evol. Microbiol., 53:661\u2013668.","journal-title":"Int. J. Syst. Evol. Microbiol."},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.47.2.559-562.2003"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.50.4.1178-1182.2006"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dki412"}],"container-title":["Microbial Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/mdr.2010.0096","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2010.0096","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2010.0096","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:25:53Z","timestamp":1777667153000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/mdr.2010.0096"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,3]]}},"alternative-id":["10.1089\/mdr.2010.0096"],"URL":"https:\/\/doi.org\/10.1089\/mdr.2010.0096","relation":{},"ISSN":["1076-6294","1931-8448"],"issn-type":[{"value":"1076-6294","type":"print"},{"value":"1931-8448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,3]]}}}