{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:24:09Z","timestamp":1777922649722,"version":"3.51.4"},"reference-count":28,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2012,12,1]],"date-time":"2012-12-01T00:00:00Z","timestamp":1354320000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:p>\n                    A recent study showed that pneumococcal pherotypes often coexist in the nasopharynx and suggested that the impact of pherotype-mediated fratricide on competition is limited. We determined the impact of pherotype (or competence-stimulating peptide [CSP]) on pneumococcal nasopharyngeal co-colonization. Of 184 nasopharyngeal samples yielding two serotypes, 39.9% contained CSP1 only, 12.6% CSP2 only, and 47.5% had one strain of each pherotype. The observed proportions of concordant and discordant pherotypes (52.5% and 47.5%, respectively), were compared with the ones estimated (53.8% and 46.2%, respectively), and there were no significant differences (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    =0.9, \u03c7\n                    <jats:sup>2<\/jats:sup>\n                    test). Our results support the hypothesis that there is a limited role of pherotype in co-colonization.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2011.0228","type":"journal-article","created":{"date-parts":[[2012,7,13]],"date-time":"2012-07-13T04:52:40Z","timestamp":1342155160000},"page":"550-554","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Pherotypes of Co-Colonizing Pneumococci Among Portuguese Children"],"prefix":"10.1177","volume":"18","author":[{"given":"Carina","family":"Valente","sequence":"first","affiliation":[{"name":"Universidade Nova de Lisboa","place":["Portugal"]},{"name":"Universidade Nova de Lisboa","place":["Portugal"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Herm\u00ednia","family":"De Lencastre","sequence":"additional","affiliation":[{"name":"Universidade Nova de Lisboa","place":["Portugal"]},{"name":"The Rockefeller University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raquel","family":"S\u00e1-Le\u00e3o","sequence":"additional","affiliation":[{"name":"Universidade Nova de Lisboa","place":["Portugal"]},{"name":"Universidade Nova de Lisboa","place":["Portugal"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2012,12]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1111\/j.1469-0691.2008.02031.x","article-title":"Changes in Streptococcus pneumoniae serotypes causing invasive disease with non-universal vaccination coverage of the seven-valent conjugate vaccine","volume":"14","author":"Aguiar S.I.","year":"2008","unstructured":"Aguiar S.I., , Serrano I., , Pinto F.R., , Melo-Cristino J., , Ramirez M. 2008. Changes in Streptococcus pneumoniae serotypes causing invasive disease with non-universal vaccination coverage of the seven-valent conjugate vaccine. Clin. Microbiol. Infect., 14:835\u2013843.","journal-title":"Clin. Microbiol. Infect."},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/171.4.890"},{"key":"e_1_3_3_4_2","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1186\/1471-2180-9-191","article-title":"Pherotypes are driving genetic differentiation within Streptococcus pneumoniae","volume":"9","author":"Carrolo M.","year":"2009","unstructured":"Carrolo M., , Pinto F.R., , Melo-Cristino J., , Ramirez M. 2009. Pherotypes are driving genetic differentiation within Streptococcus pneumoniae. 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