{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:24:46Z","timestamp":1777922686683,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T00:00:00Z","timestamp":1406851200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:p>\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Aim:<\/jats:italic>\n                    <\/jats:bold>\n                    Active surveillance of plasmid-mediated \u03b2-lactamase-producing\n                    <jats:italic toggle=\"yes\">Enterobacteriaceae<\/jats:italic>\n                    (PMBL-E) in fecal carriers in the hospital and in the community setting in a non-outbreak period of time.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Methods:<\/jats:italic>\n                    <\/jats:bold>\n                    Patients were screened for carriage of\n                    <jats:italic toggle=\"yes\">Enterobacteriaceae<\/jats:italic>\n                    resistant to expanded-spectrum cephalosporins and PMBL-E were characterized (extended-spectrum-\u03b2-lactamase [ESBL], plasmid-mediated AmpC \u03b2-lactamase [pAmpC], and carbapenemases) by PCR and sequencing.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Results:<\/jats:italic>\n                    <\/jats:bold>\n                    The prevalence of ESBL and pAmpC carriers was 5.06% and 0.59%, respectively. Overall, CTX-M-like enzymes were the ESBL dominate enzymes (96.15%). The group CTX-M-9 was the most prevalent (81, 54%) [CTX-M-14 (74, 91.35%), CTX-M-9 (5, 6.17%), CTX-M-24 (1, 1.23%), and CTX-M-27 (1, 1.23%)] followed by the group CTX-M-1 (64, 42.67%) [CTX-M-15 (42, 65.63%), CTX-M-1 (13, 20.31%), CTX-M-32 (8, 12.5%), and CTX-M-3 (1, 1.56%)]. One CTX-M-10, one CTX-M-59, and three CTX-M-8 were also found. A very small representation of SHV or TEM ESBL enzymes was found (3.2% and 0.64%, respectively). pAmpC characterization revealed a predominance of CMY-2 (81.25%), followed by DHA-1 (18.75%). We did not detect the presence of carbapenemase producers.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Conclusions:<\/jats:italic>\n                    <\/jats:bold>\n                    The prevalence of ESBL-producers from fecal carriers is stable in our area, but colonization by pAmpC producers has emerged recently as we have confirmed. Periodic active surveillance is useful to identify these human reservoirs and control the evolution of PMBL carriage in a community over time.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2013.0109","type":"journal-article","created":{"date-parts":[[2013,12,13]],"date-time":"2013-12-13T13:22:01Z","timestamp":1386940921000},"page":"301-304","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":18,"title":["Characterization of Plasmid-Mediated \u03b2-Lactamases in Fecal Colonizing Patients in the Hospital and Community Setting in Spain"],"prefix":"10.1177","volume":"20","author":[{"given":"Ana","family":"Garrido","sequence":"first","affiliation":[{"name":"Hospital Cl\u00ednico Universitario \u201cLozano Blesa,\u201d","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Seral","sequence":"additional","affiliation":[{"name":"Hospital Cl\u00ednico Universitario \u201cLozano Blesa,\u201d","place":["Spain"]},{"name":"Universidad de Zaragoza","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Jos\u00e9","family":"Gude","sequence":"additional","affiliation":[{"name":"Hospital Cl\u00ednico Universitario \u201cLozano Blesa,\u201d","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Casado","sequence":"additional","affiliation":[{"name":"Universidad de La Rioja","place":["Spain"]},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica de La Rioja","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda","family":"Gonz\u00e1lez-Dom\u00ednguez","sequence":"additional","affiliation":[{"name":"Hospital Cl\u00ednico Universitario \u201cLozano Blesa,\u201d","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yolanda","family":"S\u00e1enz","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica de La Rioja","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco Javier","family":"Castillo","sequence":"additional","affiliation":[{"name":"Hospital Cl\u00ednico Universitario \u201cLozano Blesa,\u201d","place":["Spain"]},{"name":"Universidad de Zaragoza","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,8]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.2009.0868"},{"key":"e_1_3_3_3_2","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/s10096-006-0242-8","article-title":"Prevalence of fecal carriage of ESBL-producing Enterobacteriaceae in hospitalized and ambulatory patients during two non-outbreak periods","volume":"26","author":"Castillo Garc\u00eda F.J.","year":"2007","unstructured":"Castillo Garc\u00eda F.J., , Seral Garc\u00eda C., , Pardos De la G\u00e1ndara M., , Mill\u00e1n Lou M.I., , and Pitart Ferre C.. 2007. 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