{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T01:21:15Z","timestamp":1778203275089,"version":"3.51.4"},"reference-count":40,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2015,4,1]],"date-time":"2015-04-01T00:00:00Z","timestamp":1427846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:p>\n                    This retrospective study was conducted to evaluate clinical outcomes of bacteremia caused by extended-spectrum \u03b2-lactamase (ESBL)\u2013producing\n                    <jats:italic toggle=\"yes\">Escherichia coli<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">Klebsiella pneumoniae<\/jats:italic>\n                    and their antibiotic susceptibilities in febrile neutropenic children. Clinical characteristics, prognosis, and antibiotic susceptibilities were reviewed and compared between febrile neutropenic children with bacteremia caused by ESBL-producing and non-ESBL-producing\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">K. pneumoniae<\/jats:italic>\n                    . A total of 61 episodes of\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">K. pneumoniae<\/jats:italic>\n                    bacteremia, including 21 episodes (34.4%) due to ESBL-producing strains, were diagnosed. There was no significant factor associated with bacteremia by ESBL-producing strains. Empirical antibiotics were appropriate in 85.7% of the ESBL group and 95.0% of the non-ESBL group. In the entire study population, seven deaths (11.5%), including three deaths (4.9%) due to\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">K. pneumoniae<\/jats:italic>\n                    bacteremia, occurred. The complication and mortality rates were not significantly different between the two groups. Antibiotic susceptibility rates were significantly lower in the ESBL group than in the non-ESBL group in most antibiotics. Although 52.4% and 66.7% of the ESBL-producing isolates were susceptible to piperacillin\/tazobactam and cefepime, respectively, 96.7% of all the isolates and 90.5% of the ESBL-producing isolates were susceptible to piperacillin\/tazobactam or cefepime in combination with aminoglycoside. In conclusion, the ESBL group did not show a significantly unfavorable outcome, and empirical therapy with piperacillin\/tazobactam or cefepime in combination with aminoglycoside might be more useful for febrile neutropenic children, instead of \u03b2-lactam monotherapy in institutions with high prevalence of ESBL-producing\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">K. pneumoniae<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.1089\/mdr.2014.0092","type":"journal-article","created":{"date-parts":[[2014,11,14]],"date-time":"2014-11-14T20:28:52Z","timestamp":1415996932000},"page":"244-251","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":18,"title":["Extended-Spectrum \u03b2-Lactamase-Producing\n                    <i>Escherichia coli<\/i>\n                    and\n                    <i>Klebsiella pneumoniae<\/i>\n                    Bacteremia in Febrile Neutropenic Children"],"prefix":"10.1177","volume":"21","author":[{"given":"Seung Beom","family":"Han","sequence":"first","affiliation":[{"name":"The Catholic University of Korea"},{"name":"The Catholic University of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung Won","family":"Jung","sequence":"additional","affiliation":[{"name":"The Catholic University of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. Young","family":"Bae","sequence":"additional","affiliation":[{"name":"The Catholic University of Korea"},{"name":"The Catholic University of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae Wook","family":"Lee","sequence":"additional","affiliation":[{"name":"The Catholic University of Korea"},{"name":"The Catholic University of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong-Gun","family":"Lee","sequence":"additional","affiliation":[{"name":"The Catholic University of Korea"},{"name":"The Catholic University of Korea"},{"name":"The Catholic University of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nack-Gyun","family":"Chung","sequence":"additional","affiliation":[{"name":"The Catholic University of Korea"},{"name":"The Catholic University of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dae Chul","family":"Jeong","sequence":"additional","affiliation":[{"name":"The Catholic University of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Cho","sequence":"additional","affiliation":[{"name":"The Catholic University of Korea"},{"name":"The Catholic University of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin Han","family":"Kang","sequence":"additional","affiliation":[{"name":"The Catholic University of Korea"},{"name":"The Catholic University of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hack-Ki","family":"Kim","sequence":"additional","affiliation":[{"name":"The Catholic University of Korea"},{"name":"The Catholic University of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yeon-Joon","family":"Park","sequence":"additional","affiliation":[{"name":"The Catholic University of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2015,4]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1086\/520214"},{"key":"e_1_3_2_3_2","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.1128\/AAC.50.5.1715-1720.2006","article-title":"Predictors of mortality in patients with bloodstream infection due to ceftazidime-resistant Klebsiella pneumoniae","volume":"50","author":"Anderson D.J.","year":"2006","unstructured":"Anderson D.J., , Engemann J.J., , Harrell L.J., , Carmeli Y., , Reller L.B., , and Kaye K.S.. 2006. 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Chemother."},{"key":"e_1_3_2_23_2","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1080\/00365540701704706","article-title":"Evaluation of detection of extended-spectrum beta-lactamases among Escherichia coli and Klebsiella spp. isolates by VITEK 2 AST-N029 compared to the agar dilution and disk diffusion methods","volume":"40","author":"Nyberg S.D.","year":"2008","unstructured":"Nyberg S.D., , Meurman O., , Jalava J., , and Rantakokko-Jalava K.. 2008. Evaluation of detection of extended-spectrum beta-lactamases among Escherichia coli and Klebsiella spp. isolates by VITEK 2 AST-N029 compared to the agar dilution and disk diffusion methods. Scand. J. Infect. Dis., 40:355\u2013362.","journal-title":"Scand. J. Infect. Dis."},{"key":"e_1_3_2_24_2","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1007\/s00277-004-0909-0","article-title":"Bacterial and fungal bloodstream isolates from 796 hematopoietic stem cell transplant recipients between 1991 and 2000","volume":"84","author":"Ortega M.","year":"2005","unstructured":"Ortega M., , Rovira M., , Almela M., , Marco F., , de la Bellacasa J.P., , and Mart\u00ednez J.A., et al. 2005. Bacterial and fungal bloodstream isolates from 796 hematopoietic stem cell transplant recipients between 1991 and 2000. Ann. Hematol., 84:40\u201346.","journal-title":"Ann. Hematol."},{"key":"e_1_3_2_25_2","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1046\/j.1469-0691.2000.00107.x","article-title":"Recommendation for treatment of severe infections caused by Enterobacteriaceae producing extended-spectrum \u00df-lactamases (ESBLs)","volume":"6","author":"Paterson D.L.","year":"2000","unstructured":"Paterson D.L. 2000. Recommendation for treatment of severe infections caused by Enterobacteriaceae producing extended-spectrum \u00df-lactamases (ESBLs). Clin. Microbiol. Infect., 6:460\u2013463.","journal-title":"Clin. Microbiol. Infect."},{"key":"e_1_3_2_26_2","doi-asserted-by":"crossref","first-page":"26","DOI":"10.7326\/0003-4819-140-1-200401060-00008","article-title":"International prospective study of Klebsiella pneumoniae bacteremia: implications of extended-spectrum \u00df-lactamase production in nosocomial infections","volume":"140","author":"Paterson D.L.","year":"2004","unstructured":"Paterson D.L., , Ko W.C., , Von Gottberg A., , Mohapatra S., , Casellas J.M., , Goossens H., et al. 2004. International prospective study of Klebsiella pneumoniae bacteremia: implications of extended-spectrum \u00df-lactamase production in nosocomial infections. Ann. Intern. Med., 140:26\u201332.","journal-title":"Ann. Intern. Med."},{"key":"e_1_3_2_27_2","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1093\/jac\/dki166","article-title":"Emergence of Enterobacteriaceae producing extended-spectrum \u00df-lactamases (ESBLs) in the community","volume":"56","author":"Pitout J.D.","year":"2005","unstructured":"Pitout J.D., , Nordmann P., , Laupland K.B., , and Poirel L.. 2005. Emergence of Enterobacteriaceae producing extended-spectrum \u00df-lactamases (ESBLs) in the community. J. Antimicrob. Chemother., 56:52\u201359.","journal-title":"J. Antimicrob. Chemother."},{"key":"e_1_3_2_28_2","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1111\/j.1469-0691.2007.01893.x","article-title":"Evaluation of the Vitek-2 extended-spectrum beta-lactamase test against non-duplicate strains of Enterobacteriaceae producing a broad diversity of well-characterised beta-lactamases","volume":"14","author":"Robin F.","year":"2008","unstructured":"Robin F., , Delmas J., , Schweitzer C., , and Bonnet R.. 2008. Evaluation of the Vitek-2 extended-spectrum beta-lactamase test against non-duplicate strains of Enterobacteriaceae producing a broad diversity of well-characterised beta-lactamases. Clin. Microbiol. Infect., 14:148\u2013154.","journal-title":"Clin. Microbiol. Infect."},{"key":"e_1_3_2_29_2","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1093\/jac\/dks065","article-title":"Effects of confounders and intermediates on the association of bacteraemia caused by extended-spectrum \u00df-lactamase-producing Enterobacteriaceae and patient outcome: a meta-analysis","volume":"67","author":"Rottier W.C.","year":"2012","unstructured":"Rottier W.C., , Ammerlaan H.S., , and Bonten M.J.. 2012. Effects of confounders and intermediates on the association of bacteraemia caused by extended-spectrum \u00df-lactamase-producing Enterobacteriaceae and patient outcome: a meta-analysis. J. Antimicrob. Chemother., 67:1311\u20131320.","journal-title":"J. Antimicrob. 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Comparative activities of cefepime and piperacillin\/tazobactam tested against a global collection of Escherichia coli and Klebsiella spp. with an ESBL phenotype. Diagn. Microbiol. Infect. Dis., 57:341\u2013344.","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"e_1_3_2_32_2","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.diagmicrobio.2004.11.001","article-title":"Acceptable performance of VITEK 2 system to detect extended-spectrum beta-lactamases in clinical isolates of Escherichia coli: a comparative study of phenotypic commercial methods and NCCLS guidelines","volume":"51","author":"Sorl\u00f3zano A.","year":"2005","unstructured":"Sorl\u00f3zano A., , Guti\u00e9rrez J., , Pi\u00e9drola G., , and Soto M.J.. 2005. Acceptable performance of VITEK 2 system to detect extended-spectrum beta-lactamases in clinical isolates of Escherichia coli: a comparative study of phenotypic commercial methods and NCCLS guidelines. Diagn. Microbiol. Infect. Dis., 51:191\u2013193.","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00433-06"},{"key":"e_1_3_2_34_2","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.jinf.2009.02.002","article-title":"Incidence and clinical impact of extended-spectrum-\u00df-lactamase (ESBL) production and fluoroquinolone resistance in bloodstream infections caused by Escherichia coli in patients with hematological malignancies","volume":"58","author":"Trecarichi E.M.","year":"2009","unstructured":"Trecarichi E.M., , Tumbarello M., , Spanu T., , Caira M., , Fianchi L., , Chiusolo P., et al. 2009. Incidence and clinical impact of extended-spectrum-\u00df-lactamase (ESBL) production and fluoroquinolone resistance in bloodstream infections caused by Escherichia coli in patients with hematological malignancies. J. Infect., 58:299\u2013307.","journal-title":"J. Infect."},{"key":"e_1_3_2_35_2","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1086\/516092","article-title":"Imipenem-resistant Pseudomonas aeruginosa: risk factors and antibiotic susceptibility patterns","volume":"25","author":"Troillet N.","year":"1997","unstructured":"Troillet N., , Samore M.H., , and Carmeli Y.. 1997. Imipenem-resistant Pseudomonas aeruginosa: risk factors and antibiotic susceptibility patterns. Clin. Infect. Dis., 25:1094\u20131098.","journal-title":"Clin. Infect. Dis."},{"key":"e_1_3_2_36_2","first-page":"481","article-title":"In vitro activity of isepamicin and other aminoglycosides against clinical isolates of Gram-negative bacteria causing nosocomial bloodstream infections","volume":"40","author":"Tsai T.Y.","year":"2007","unstructured":"Tsai T.Y., , Chang S.C., , Hsueh P.R., , Feng N.H., , and Wang J.T.. 2007. 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Detection of extended-spectrum beta-lactamases among Enterobacteriaceae by use of semiautomated microbiology systems and manual detection procedures. J. Clin. Microbiol., 45:1167\u20131174.","journal-title":"J. Clin. Microbiol."},{"key":"e_1_3_2_40_2","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1093\/jac\/dkh424","article-title":"Community and hospital spread of Escherichia coli producing CTX-M extended-spectrum \u00df-lactamases in the UK","volume":"54","author":"Woodford N.","year":"2004","unstructured":"Woodford N., , Ward M.E., , Kaufmann M.E., , Turton J., , Fagan E.J., , James D., et al. 2004. Community and hospital spread of Escherichia coli producing CTX-M extended-spectrum \u00df-lactamases in the UK. J. Antimicrob. Chemother., 54:735\u2013743.","journal-title":"J. Antimicrob. 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