{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T23:50:08Z","timestamp":1789343408995,"version":"build-2803163510"},"reference-count":51,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:p>\n                    The aim of this study was to evaluate the antimicrobial susceptibility profile of 85\n                    <jats:italic toggle=\"yes\">Staphylococcus epidermidis<\/jats:italic>\n                    and 84\n                    <jats:italic toggle=\"yes\">Staphylococcus haemolyticus<\/jats:italic>\n                    strains isolated from blood cultures to oxacillin, vancomycin, tigecycline, linezolid, daptomycin, and quinupristin\/dalfopristin over a period of 12 years.\n                    <jats:italic toggle=\"yes\">S. epidermidis<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">S. haemolyticus<\/jats:italic>\n                    isolated from blood cultures of inpatients, attended at a teaching hospital, were analyzed for the presence of the\n                    <jats:italic toggle=\"yes\">mecA<\/jats:italic>\n                    gene and by SCC\n                    <jats:italic toggle=\"yes\">mec<\/jats:italic>\n                    typing. The minimum inhibitory concentration (MIC) values of tigecycline, linezolid, daptomycin, quinupristin\/dalfopristin, and vancomycin were determined. Isolates exhibiting vancomycin MICs of \u22652\u2009\u03bcg\/ml were typed by pulsed-field gel electrophoresis (PFGE). The rate of\n                    <jats:italic toggle=\"yes\">mecA<\/jats:italic>\n                    positivity was 92.9% and 100% in\n                    <jats:italic toggle=\"yes\">S. epidermidis<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">S. haemolyticus<\/jats:italic>\n                    , respectively. The most frequent SCC\n                    <jats:italic toggle=\"yes\">mec<\/jats:italic>\n                    types were type III (53.2%) in\n                    <jats:italic toggle=\"yes\">S. epidermidis<\/jats:italic>\n                    and type I (32.1%) in\n                    <jats:italic toggle=\"yes\">S. haemolyticus<\/jats:italic>\n                    . All isolates were susceptible to linezolid and daptomycin, but 7.1% of\n                    <jats:italic toggle=\"yes\">S. haemolyticus<\/jats:italic>\n                    and 2.3% of\n                    <jats:italic toggle=\"yes\">S. epidermidis<\/jats:italic>\n                    isolates were resistant to tigecycline, and 1.2% each of\n                    <jats:italic toggle=\"yes\">S. haemolyticus<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">S. epidermidis<\/jats:italic>\n                    were resistant and intermediately resistant to quinupristin\/dalfopristin, respectively.\n                    <jats:italic toggle=\"yes\">S. epidermidis<\/jats:italic>\n                    exhibited higher vancomycin MICs (40% with MIC of \u22652\u2009\u03bcg\/ml). Clonal typing of strains with vancomycin MIC of \u22652\u2009\u03bcg\/ml revealed the presence of different PFGE types of\n                    <jats:italic toggle=\"yes\">S. epidermidis<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">S. haemolyticus<\/jats:italic>\n                    over a period of up to 4 years (2002\u20132004, 2005\u20132008, 2006\u20132009, 2010\u20132011). Despite the observation of a high prevalence of\n                    <jats:italic toggle=\"yes\">mecA<\/jats:italic>\n                    , the clinical strains were fully susceptible to vancomycin and to the new drugs linezolid, daptomycin, tigecycline, and quinupristin\/dalfopristin. The PFGE types with vancomycin MIC of \u22652\u2009\u03bcg\/ml exhibited a great diversity of SCC\n                    <jats:italic toggle=\"yes\">mec<\/jats:italic>\n                    cassettes, demonstrating that\n                    <jats:italic toggle=\"yes\">S. epidermidis<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">S. haemolyticus<\/jats:italic>\n                    may easily acquire these resistance-conferring genetic elements.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2015.0064","type":"journal-article","created":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T13:21:00Z","timestamp":1448976060000},"page":"283-293","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":22,"title":["Susceptibility Profile of\n                    <i>Staphylococcus epidermidis<\/i>\n                    and\n                    <i>Staphylococcus haemolyticus<\/i>\n                    Isolated from Blood Cultures to Vancomycin and Novel Antimicrobial Drugs over a Period of 12 Years"],"prefix":"10.1177","volume":"22","author":[{"given":"Luiza","family":"Pinheiro","sequence":"first","affiliation":[{"name":"Universidade Estadual Paulista (UNESP)","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla Ivo","family":"Brito","sequence":"additional","affiliation":[{"name":"Universidade Estadual Paulista (UNESP)","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9ria Cataneli","family":"Pereira","sequence":"additional","affiliation":[{"name":"Universidade Estadual Paulista (UNESP)","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adilson","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Universidade Estadual Paulista (UNESP)","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariane Rocha","family":"Bartolomeu","sequence":"additional","affiliation":[{"name":"Universidade Estadual Paulista (UNESP)","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos Henrique","family":"Camargo","sequence":"additional","affiliation":[{"name":"Universidade Estadual Paulista (UNESP)","place":["Brazil"]},{"name":"Instituto Adolfo Lutz","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Lourdes Ribeiro Souza","family":"Cunha","sequence":"additional","affiliation":[{"name":"Universidade Estadual Paulista (UNESP)","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,6]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/039139880602900409"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.37.8.1563"},{"key":"e_1_3_3_4_2","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1128\/JCM.44.1.229-231.2006","article-title":"Does nasal cocolonization by methicillin-resistant coagulase-negative staphylococci and methicillin-susceptible Staphylococcus aureus strains occur frequently enough to represent a risk of false-positive methicillin-resistant S. aureus determinations by molecular methods?","volume":"44","author":"Becker K.","year":"2006","unstructured":"Becker K., , Pagnier I., , Schuhen B., , Wenzelburger F., , Friedrich A.W., , Kipp F., , Peters G., , and von Eiff C. 2006. Does nasal cocolonization by methicillin-resistant coagulase-negative staphylococci and methicillin-susceptible Staphylococcus aureus strains occur frequently enough to represent a risk of false-positive methicillin-resistant S. aureus determinations by molecular methods?. J. Clin. Microbiol. 44:229\u2013231.","journal-title":"J. Clin. Microbiol"},{"key":"e_1_3_3_5_2","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1111\/j.1469-0691.2005.01150.x","article-title":"Predominance of staphylococcal cassette chromosome mec (SCCmec) type IV among methicillin-resistant Staphylococcus aureus (MRSA) in a Swedish county and presence of unknown SCCmec types with Panton-Valentine leukocidin genes","volume":"11","author":"Berglund C.","year":"2005","unstructured":"Berglund C., , M\u00f6lling P., , Sj\u00f6berg L., , and S\u00f6derquist B. 2005. Predominance of staphylococcal cassette chromosome mec (SCCmec) type IV among methicillin-resistant Staphylococcus aureus (MRSA) in a Swedish county and presence of unknown SCCmec types with Panton-Valentine leukocidin genes. Clin. Microbiol. Infect. 11:447\u2013456.","journal-title":"Clin. Microbiol. Infect"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s100960000299"},{"key":"e_1_3_3_7_2","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.diagmicrobio.2008.01.019","article-title":"In vitro activity of daptomycin against methicillin- and multiresistant Staphylococcus haemolyticus invasive isolates carrying different mec complexes","volume":"61","author":"Campanile F.","year":"2008","unstructured":"Campanile F., , Bongiorno D., , Borbone S., , Falcone M., , Giannella M., , Venditti M., , and Stefani S. 2008. In vitro activity of daptomycin against methicillin- and multiresistant Staphylococcus haemolyticus invasive isolates carrying different mec complexes. Diagn. Microbiol. Infect. Dis. 61:227\u2013231.","journal-title":"Diagn. Microbiol. Infect. Dis"},{"key":"e_1_3_3_8_2","doi-asserted-by":"crossref","first-page":"2311","DOI":"10.1128\/AAC.37.11.2311","article-title":"Characterization of glycopeptide-resistant enterococci from U.S","volume":"37","author":"Clark N.C.","year":"1993","unstructured":"Clark N.C., , Cooksey R.C., , Hill B.C., , Swenson J.M., , and Tenover F.C. 1993. Characterization of glycopeptide-resistant enterococci from U.S. hospitals. Antimicrob. Agents Chemother. 37:2311\u20132317.","journal-title":"hospitals. Antimicrob. Agents Chemother"},{"key":"e_1_3_3_9_2","volume-title":"CLSI Document M100-S23","author":"Clinical and Laboratory Standards Institute (CLSI)","year":"2013","unstructured":"Clinical and Laboratory Standards Institute (CLSI). 2013. Performance Standards for Antimicrobial Susceptibility Testing; approved standard. CLSI Document M100-S23. Clinical and Laboratory Standards Institute, Wayne, PA."},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.39.9.3099-3103.2001"},{"key":"e_1_3_3_11_2","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1590\/S0074-02762004000800012","article-title":"Comparison of methods for identification of Coagulase-negative Staphylococci","volume":"99","author":"Cunha M.L.R.S.","year":"2004","unstructured":"Cunha M.L.R.S., , Sinzato Y.K., , and Silveira L.V.A.. 2004. Comparison of methods for identification of Coagulase-negative Staphylococci. Mem. Inst. Oswaldo Cruz, 99:855\u2013860.","journal-title":"Mem. Inst. Oswaldo Cruz"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1086\/320184"},{"key":"e_1_3_3_13_2","unstructured":"European Committee on Antimicrobial Susceptibility Testing (EUCAST). 2013. Breakpoint tables for interpretation of MICs and zone diameters version 3.1. Available at http:\/\/www.eucast.org (Online accessed December16 2014)."},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01729-10"},{"key":"e_1_3_3_15_2","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1128\/AAC.02112-12","article-title":"Linezolid surveillance results for the United States: LEADER surveillance program 2011","volume":"57","author":"Flamm R.K.","year":"2013","unstructured":"Flamm R.K., , Mendes R.E., , Ross J.E., , Sader H.S., , and Jones R.N. 2013. Linezolid surveillance results for the United States: LEADER surveillance program 2011. Antimicrob. Agents Chemother. 57:1077\u20131081.","journal-title":"Antimicrob. Agents Chemother"},{"key":"e_1_3_3_16_2","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.diagmicrobio.2007.10.017","article-title":"Tigecycline activity tested against 11808 bacterial pathogens recently collected from US medical centers","volume":"60","author":"Gales A.C.","year":"2008","unstructured":"Gales A.C., , Sader H.S., , and Fritsche T.R. 2008. Tigecycline activity tested against 11808 bacterial pathogens recently collected from US medical centers. Diagn. Microbiol. Infect. Dis. 60:421\u2013427.","journal-title":"Diagn. Microbiol. Infect. Dis"},{"key":"e_1_3_3_17_2","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1128\/AAC.48.6.2179-2184.2004","article-title":"Effects of efflux transporter genes on susceptibility of Escherichia coli to tigecycline (GAR-936)","volume":"48","author":"Hirata T.","year":"2004","unstructured":"Hirata T., , Saito A., , Nishino K., , Tamura N., , and Yamaguchi A. 2004. Effects of efflux transporter genes on susceptibility of Escherichia coli to tigecycline (GAR-936). Antimicrob. Agents Chemother. 48:179\u20132184.","journal-title":"Antimicrob. Agents Chemother"},{"key":"e_1_3_3_18_2","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1093\/jac\/dkn353","article-title":"Non-susceptibility trends among staphylococci from bacteraemias in the UK and Ireland, 2001\u20132006","volume":"62","author":"Hope R.","year":"2008","unstructured":"Hope R., , Livermore D.M., , Brick G., , Lillie M., , Reynolds R., and BSAC Working Parties on Resistance Surveillance. 2008. Non-susceptibility trends among staphylococci from bacteraemias in the UK and Ireland, 2001\u20132006. J. Antimicrob. Chemother. 62:65\u201374.","journal-title":"J. Antimicrob. Chemother"},{"key":"e_1_3_3_19_2","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1007\/s00284-012-0278-1","article-title":"Vancomycin-resistant gram-positive cocci isolated from the saliva of wild songbirds","volume":"66","author":"Ishihara S.","year":"2013","unstructured":"Ishihara S., , Bitner J.J., , Farley G.H., , and Gillock E.T. 2013. Vancomycin-resistant gram-positive cocci isolated from the saliva of wild songbirds. Curr. Microbiol. 66:337\u2013343.","journal-title":"Curr. Microbiol"},{"key":"e_1_3_3_20_2","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1099\/jmm.0.000080","article-title":"Increase in SCCmec type IV strains effects trends in antibiograms of methicillin-resistant Staphylococcus aureus at a tertiary care hospital","volume":"64","author":"Ito A.","year":"2015","unstructured":"Ito A., , Nakaminami H., , Fujii T., , Utsumi K., , and Noguchi N. 2015. Increase in SCCmec type IV strains effects trends in antibiograms of methicillin-resistant Staphylococcus aureus at a tertiary care hospital. J. Med. Microbiol. 64:745\u2013751.","journal-title":"J. Med. Microbiol"},{"key":"e_1_3_3_21_2","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1128\/AAC.32.2.202","article-title":"Low-level colonization of hospitalized patients with methicillin-resistant coagulase-negative staphylococci and emergence of the organisms during surgical antimicrobial prophylaxis","volume":"32","author":"Kernodle D.S.","year":"1988","unstructured":"Kernodle D.S., , Barg N.L., , and Kaiser A.B. 1988. Low-level colonization of hospitalized patients with methicillin-resistant coagulase-negative staphylococci and emergence of the organisms during surgical antimicrobial prophylaxis. Antimicrob. Agents Chemother. 32:202\u2013208.","journal-title":"Antimicrob. Agents Chemother"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00165-06"},{"key":"e_1_3_3_23_2","unstructured":"Koneman E.W. Allen S.D. Janda W.M. Schreckenberger P.C. and Winn W.C. 1997. Color Atlas and Textbook of Diagnostic Microbiology. 5th ed. Lippincott Philadelphia PA."},{"key":"e_1_3_3_24_2","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1111\/j.1600-0609.2007.00945.x","article-title":"In vitro activity of daptomycin and tigecycline against coagulase-negative Staphylococcus blood isolates from bone marrow transplant recipients","volume":"79","author":"Kratzer C.","year":"2007","unstructured":"Kratzer C., , Rabitsch W., , Hirschl A.M., , Graninger W., , and Presterl E. 2007. In vitro activity of daptomycin and tigecycline against coagulase-negative Staphylococcus blood isolates from bone marrow transplant recipients. Eur. J. Haematol. 79:405\u2013409.","journal-title":"Eur. J. Haematol"},{"key":"e_1_3_3_25_2","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1099\/jmm.0.47294-0","article-title":"Distribution of staphylococcal cassette chromosome mec (SCCmec) types I, II, III and IV in coagulase-negative staphylococci from patients attending a tertiary hospital in southern Brazil","volume":"56","author":"Machado A.B.","year":"2007","unstructured":"Machado A.B., , Reiter K.C., , Paiva R.M., , and Barth A.L. 2007. Distribution of staphylococcal cassette chromosome mec (SCCmec) types I, II, III and IV in coagulase-negative staphylococci from patients attending a tertiary hospital in southern Brazil. J. Med. Microbiol. 56:1328\u20131333.","journal-title":"J. Med. Microbiol"},{"key":"e_1_3_3_26_2","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/S1413-8670(10)70020-9","article-title":"Novel pharmaceutical molecules against emerging resistant gram-positive cocci","volume":"14","author":"Manfredi R.","year":"2010","unstructured":"Manfredi R., , and Sabbatani S. 2010. Novel pharmaceutical molecules against emerging resistant gram-positive cocci. Braz. J. Infect. Dis. 14:96\u2013108.","journal-title":"Braz. J. Infect. Dis"},{"key":"e_1_3_3_27_2","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/586076","article-title":"Neonatal sepsis due to coagulase-negative staphylococci","author":"Marchant E.A.","year":"2013","unstructured":"Marchant E.A., , Boyce G.K., , Sadarangani M., , and Lavoie P.M. 2013. Neonatal sepsis due to coagulase-negative staphylococci. Clin. Dev. Immunol. [Epub ahead of print]; DOI: 10.1155\/2013\/586076.","journal-title":"Clin. Dev. Immunol"},{"key":"e_1_3_3_28_2","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1128\/AAC.01908-13","article-title":"Trends in antibiotic resistance in coagulase-negative staphylococci in the United States, 1999 to 2012","volume":"58","author":"May L.","year":"2014","unstructured":"May L., , Klein E.Y., , Rothman R.E., , and Laxminarayan R. 2014. Trends in antibiotic resistance in coagulase-negative staphylococci in the United States, 1999 to 2012. Antimicrob. Agents Chemother. 58:1404\u20131409.","journal-title":"Antimicrob. Agents Chemother"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.5.1865-1871.2005"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.11.5113-5120.2003"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01685-07"},{"key":"e_1_3_3_32_2","doi-asserted-by":"crossref","first-page":"2540","DOI":"10.1128\/JB.01484-06","article-title":"Inferring a population structure for Staphylococcus epidermidis from multilocus sequence typing data","volume":"189","author":"Miragaia M.","year":"2007","unstructured":"Miragaia M., , Thomas J.C., , Couto I., , Enright M.C., , and Lencastre H. 2007. Inferring a population structure for Staphylococcus epidermidis from multilocus sequence typing data. J. Bacteriol. 189:2540\u20132552.","journal-title":"J. Bacteriol"},{"key":"e_1_3_3_33_2","first-page":"2398","article-title":"Vancomycin in vitro bactericidal activity and its relationship to efficacy in clearance of methicillin-resistant Staphylococcus aureus bacteremia","volume":"42","author":"Moise-Broder P.A.","year":"2007","unstructured":"Moise-Broder P.A., , Sakoulas G., , Forrest A., , and Schentag J.J. 2007. Vancomycin in vitro bactericidal activity and its relationship to efficacy in clearance of methicillin-resistant Staphylococcus aureus bacteremia. Antimicrob. Agents Chemother. 42:2398\u20132402.","journal-title":"Antimicrob. Agents Chemother"},{"key":"e_1_3_3_34_2","unstructured":"Murray B.E. and Nannini E.C. 2005. Glycopeptides (vancomycin and teicoplanin) streptogramins (quinupristin-dalfopristin) and lipopeptids (daptomycin). In: Mandell G.L. Bennett J.E. and Dolin R. (eds.) Principles and Practice of Infectious Diseases. Churchill Livingstone Philadelphia PA pp. 417\u2013434."},{"key":"e_1_3_3_35_2","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1186\/1471-2334-9-83","article-title":"Characterization of coagulase-negative staphylococcal isolates from blood with reduced susceptibility to glycopeptides and therapeutic options","volume":"9","author":"Natoli S.","year":"2009","unstructured":"Natoli S., , Fontana C., , and Favaro M. 2009. Characterization of coagulase-negative staphylococcal isolates from blood with reduced susceptibility to glycopeptides and therapeutic options. BMC Infect. Dis. 9:83.","journal-title":"BMC Infect. Dis"},{"key":"e_1_3_3_36_2","doi-asserted-by":"crossref","first-page":"242","DOI":"10.3855\/jidc.2007","article-title":"Prevalence of virulence determinants in Staphylococcus epidermidis from ICU patients in Kampala, Uganda","volume":"6","author":"Okee M.S.","year":"2012","unstructured":"Okee M.S., , Joloba M.L., , Okello M., , Najjuka F.C., , Katabazi F.A., , Bwanga F., , Nanteza A., , and Kateete D.P. 2012. Prevalence of virulence determinants in Staphylococcus epidermidis from ICU patients in Kampala, Uganda. J. Infect. Dev. Ctries. 6:242\u2013250.","journal-title":"J. Infect. Dev. Ctries"},{"key":"e_1_3_3_37_2","doi-asserted-by":"crossref","first-page":"4289","DOI":"10.1128\/JCM.40.11.4289-4294.2002","article-title":"Dissemination of new methicillin\u2010resistant Staphylococcus aureus clones in the community","volume":"40","author":"Okuma K.","year":"2002","unstructured":"Okuma K., , Iwakawa K., , Turnidge J.D., , Grubb W.B., , Bell J.M., , O'Brien F.G., , Coombs G.W., , Pearman J.W., , Tenover F.C., , Kapi M., , Tiensasitorn C., , Ito T., , and Hiramatsu K. 2002. Dissemination of new methicillin\u2010resistant Staphylococcus aureus clones in the community. J. Clin. Microbiol. 40:4289\u20134294.","journal-title":"J. Clin. Microbiol"},{"key":"e_1_3_3_38_2","first-page":"25","article-title":"Activity of vancomycin, teicoplanin and linezolid in methicillin resistant coagulase-negative Staphylococci isolates from pediatric blood cultures","volume":"25","author":"Olivares M.F.","year":"2012","unstructured":"Olivares M.F., , Orozco R.H., , Garrido S.R., , \u00c1lvarez C.G., , Silos R.M.S., , Rastrollo R.H., , Tallo E.M., , and Carrasco J.L.C. 2012. Activity of vancomycin, teicoplanin and linezolid in methicillin resistant coagulase-negative Staphylococci isolates from pediatric blood cultures. Ver. Esp. Quimioter. 25:25\u201330.","journal-title":"Ver. Esp. Quimioter"},{"key":"e_1_3_3_39_2","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1590\/0074-0276140120","article-title":"Reduced susceptibility to vancomycin and biofilm formation in methicillin-resistant Staphylococcus epidermidis isolated from blood cultures","volume":"109","author":"Pinheiro L.","year":"2014","unstructured":"Pinheiro L., , Brito C.I., , Pereira V.C., , de Oliveira A., , Camargo C.H., , and Cunha M.L.R.S. 2014. Reduced susceptibility to vancomycin and biofilm formation in methicillin-resistant Staphylococcus epidermidis isolated from blood cultures. Mem. Inst. Oswaldo Cruz. 109:871\u2013878.","journal-title":"Mem. Inst. Oswaldo Cruz"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1086\/505114"},{"key":"e_1_3_3_41_2","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1128\/AAC.00724-08","article-title":"Diversity of staphylococcal cassette chromosome mec structures in methicillin-resistant Staphylococcus epidermidis and Staphylococcus haemolyticus strains among outpatients from four countries","volume":"53","author":"Rupp\u00e9 E.","year":"2009","unstructured":"Rupp\u00e9 E., , Barbier F., , Mesli Y., , Maiga A., , Cojocaru R., , Benkhalfat M., , Benchouk S., , Hassaine H., , Maiga I., , Diallo A., , Koumare A.K., , Ouattara K., , Soumare S., , Dufourcq J.B., , Nareth C., , Sarthou J.L., , Adremont A., , and Ruimy R. 2009. Diversity of staphylococcal cassette chromosome mec structures in methicillin-resistant Staphylococcus epidermidis and Staphylococcus haemolyticus strains among outpatients from four countries. Antimicrob. Agents Chemother. 53:442\u2013449.","journal-title":"Antimicrob. Agents Chemother"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmm.2010.04.011"},{"key":"e_1_3_3_43_2","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.ijantimicag.2010.11.020","article-title":"Susceptibility patterns of coagulase-negative staphylococci to several newer antimicrobial agents in comparison with vancomycin and oxacillin","volume":"37","author":"Stuart I.","year":"2011","unstructured":"Stuart I., , John M.A., , Milburn S., , Diagre D., , Wilson B., , and Hussain Z. 2011. Susceptibility patterns of coagulase-negative staphylococci to several newer antimicrobial agents in comparison with vancomycin and oxacillin. Int. J. Antimicrob. Agents, 37:248\u2013252.","journal-title":"Int. J. Antimicrob. Agents"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.187.21.7292-7308.2005"},{"key":"e_1_3_3_45_2","unstructured":"US Food and Drug Administration (FDA). 2013. Highlights of Prescribing Information. Tygacil\u00ae. Document 3379756. Food and Drug Administration. Available at http:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2013\/021821s026s031lbl.pdf (Online accessed December15 2014)."},{"key":"e_1_3_3_46_2","doi-asserted-by":"crossref","DOI":"10.5171\/2012.164822","article-title":"Methods for detection of oxacillin resistance among coagulase-negative staphylococci recovered from patients with bloodstream infections at the university hospital in Brazil","author":"Ustulin D.R.","year":"2012","unstructured":"Ustulin D.R., , and Cunha M.L.R.S. 2012. Methods for detection of oxacillin resistance among coagulase-negative staphylococci recovered from patients with bloodstream infections at the university hospital in Brazil. J. Virol. Microbiol. [Epub ahead of print]; DOI: 10.5171\/2012.164822.","journal-title":"J. Virol. Microbiol"},{"key":"e_1_3_3_47_2","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1086\/377452","article-title":"Expression of biofilm-associated genes and in vivo foreign body infections","volume":"188","author":"Vandecasteele S.J.","year":"2003","unstructured":"Vandecasteele S.J., , Peetermans W.E., , Merckx R., , and Van Eldere J. 2003. Expression of biofilm-associated genes and in vivo foreign body infections. J. Infect. Dis. 188:730\u2013737.","journal-title":"J. Infect. Dis"},{"key":"e_1_3_3_48_2","first-page":"20","article-title":"Mechanism of action of streptogramins and macrolides","volume":"1","author":"Vannuffel P.","year":"1996","unstructured":"Vannuffel P., , and Cocito C. 1996. Mechanism of action of streptogramins and macrolides. Drugs 51 Suppl, 1:20\u201330.","journal-title":"Drugs 51 Suppl"},{"key":"e_1_3_3_49_2","doi-asserted-by":"crossref","first-page":"3586","DOI":"10.1128\/JCM.39.10.3586-3590.2001","article-title":"Methicillin-resistant, quinupristin-dalfopristin-resistant Staphylococcus aureus with reduced sensitivity to glycopeptides","volume":"39","author":"Werner G.","year":"2001","unstructured":"Werner G., , Cuny C., , Schmitz F.J., , and Witte W. 2001. Methicillin-resistant, quinupristin-dalfopristin-resistant Staphylococcus aureus with reduced sensitivity to glycopeptides. J. Clin. Microbiol. 39:3586\u20133590.","journal-title":"J. Clin. Microbiol"},{"key":"e_1_3_3_50_2","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1080\/00365540903146987","article-title":"Clonality among multidrug-resistant hospital associated Staphylococcus epidermidis in northern Europe","volume":"41","author":"Widerstr\u00f6m M.","year":"2009","unstructured":"Widerstr\u00f6m M., , Monsen T., , Karlsson C., , Edebro H., , Johansson A., , and Wistr\u00f6m J. 2009. Clonality among multidrug-resistant hospital associated Staphylococcus epidermidis in northern Europe. Scand. J. Infect. Dis. 41:642\u2013649.","journal-title":"Scand. J. Infect. Dis"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-011-1270-6"},{"key":"e_1_3_3_52_2","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.diagmicrobio.2012.03.003","article-title":"Antimicrobial resistance trends among 5608 clinical gram-positive isolates in China: results from the gram-positive cocci resistance surveillance program (2005\u20132010)","volume":"73","author":"Zhao C.","year":"2012","unstructured":"Zhao C., , Sun H., , Wang H., , Liu Y., , Hu B., , Yu Y., , Sun Z., , Chu Y., , Cao B., , Liao K., , Lei J., , Hu Z., , Zhang L., , Zhang X., , Xu Y., , Wang Z., , and Chen M. 2012. Antimicrobial resistance trends among 5608 clinical gram-positive isolates in China: results from the gram-positive cocci resistance surveillance program (2005\u20132010). Diagn. Microbiol. Infect. Dis. 73:174\u2013181.","journal-title":"Diagn. Microbiol. Infect. Dis"}],"container-title":["Microbial Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/mdr.2015.0064","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2015.0064","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2015.0064","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:29:25Z","timestamp":1777667365000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/mdr.2015.0064"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6]]},"references-count":51,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,6]]}},"alternative-id":["10.1089\/mdr.2015.0064"],"URL":"https:\/\/doi.org\/10.1089\/mdr.2015.0064","relation":{},"ISSN":["1076-6294","1931-8448"],"issn-type":[{"value":"1076-6294","type":"print"},{"value":"1931-8448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,6]]}}}