{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:26:41Z","timestamp":1777922801627,"version":"3.51.4"},"reference-count":39,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2017,7,1]],"date-time":"2017-07-01T00:00:00Z","timestamp":1498867200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2017,7]]},"abstract":"\n We characterized extended-spectrum \u03b2-lactamases (ESBL) enzymes among\n Salmonella<\/jats:italic>\n strains isolated in Brazil from 2009 to 2014.\n Salmonella<\/jats:italic>\n recovered from both clinical and nonhuman (food, poultry, and environment) sources were subjected to antimicrobial susceptibility testing. \u03b2-lactamases genes were detected by polymerase chain reaction\/sequencing; plasmid profiles and transferability were assessed by S1-pulsed field gel electrophoresis (PFGE). Genetic diversity was evaluated by\n Xba<\/jats:italic>\n I-PFGE. Out of 630\n Salmonella<\/jats:italic>\n strains screened, 46 displayed ESBL phenotype, distributed across 11 different serotypes.\n bla<\/jats:italic>\n CTX-M-8<\/jats:sub>\n and\n bla<\/jats:italic>\n CTX-M-2<\/jats:sub>\n genes were detected at frequencies of 47% and 41%, respectively.\n bla<\/jats:italic>\n SHV-5<\/jats:sub>\n and\n bla<\/jats:italic>\n SHV-2<\/jats:sub>\n were also detected but in lower frequencies (4%, 2%).\n bla<\/jats:italic>\n TEM-1<\/jats:sub>\n gene was detected in 22% of the strains. Most of the ESBL genes were transferable by conjugation, and the respective\n bla<\/jats:italic>\n ESBL<\/jats:sub>\n gene was detected in the recipient strain, indicating the location of ESBL determinants on transferable plasmids.\n Xba<\/jats:italic>\n I-PFGE revealed genomic diversity of\n Salmonella<\/jats:italic>\n Typhimurium bearing\n bla<\/jats:italic>\n CTX-M-2<\/jats:sub>\n ,\n bla<\/jats:italic>\n CTX-M-8<\/jats:sub>\n ,\n bla<\/jats:italic>\n TEM-1<\/jats:sub>\n , and\n bla<\/jats:italic>\n SHV-2<\/jats:sub>\n genes.\n Salmonella<\/jats:italic>\n Muenchen (harboring\n bla<\/jats:italic>\n CTX-M-2<\/jats:sub>\n ) and\n Salmonella<\/jats:italic>\n Corvallis (\n bla<\/jats:italic>\n CTX-M-8<\/jats:sub>\n and\n bla<\/jats:italic>\n SHV-5<\/jats:sub>\n ) showed clonal relatedness within respective serotypes. Our findings underscore the occurrence of diverse ESBL genes in several\n Salmonella<\/jats:italic>\n serotypes, reinforcing the need for continuous surveillance of resistance genes circulating in human and nonhuman sources.\n <\/jats:p>","DOI":"10.1089\/mdr.2016.0085","type":"journal-article","created":{"date-parts":[[2016,11,9]],"date-time":"2016-11-09T17:00:34Z","timestamp":1478710834000},"page":"580-589","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":20,"title":["Prevalence of Extended-Spectrum \u03b2-Lactamases CTX-M-8 and CTX-M-2-Producing\n Salmonella<\/i>\n Serotypes from Clinical and Nonhuman Isolates in Brazil"],"prefix":"10.1177","volume":"23","author":[{"given":"Sueli Aparecida","family":"Fernandes","sequence":"first","affiliation":[{"name":"Centro de Bacteriologia","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos Henrique","family":"Camargo","sequence":"additional","affiliation":[{"name":"Centro de Bacteriologia","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriela Rodrigues","family":"Francisco","sequence":"additional","affiliation":[{"name":"Centro de Bacteriologia","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Fernanda Campagnari","family":"Bueno","sequence":"additional","affiliation":[{"name":"Centro de Bacteriologia","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doroti Oliveira","family":"Garcia","sequence":"additional","affiliation":[{"name":"Centro de Bacteriologia","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yohei","family":"Doi","sequence":"additional","affiliation":[{"name":"University of Pittsburgh School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monique Ribeiro Tiba","family":"Casas","sequence":"additional","affiliation":[{"name":"Centro de Bacteriologia","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,7]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1093\/jac\/dkt469","article-title":"Resistance to third-generation cephalosporins in human non-typhoidal Salmonella enterica isolates from England, and Wales, 2010\u201312","volume":"69","author":"Burke L.","year":"2014","unstructured":"Burke L., , Hopkins K.L., , Meunier D., , de Pinna E., , Fitzgerald-Hughes D., , Humphreys H., , and Woodford N.. 2014. 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Ctries."},{"key":"e_1_3_3_36_2","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.1128\/AAC.01854-12","article-title":"Evidence for recent acquisition and successful transmission of bla\n (CTX-M-15) in Salmonella enterica in South Korea","volume":"57","author":"Kang M.S.","year":"2013","unstructured":"Kang M.S., , Kwon Y.K., , Oh J.Y., , Kim M.J., , Call D.R., , An B.K., , Shin E.G., , Song E.A., , and Kwon J.H.. 2013. Evidence for recent acquisition and successful transmission of bla(CTX-M-15) in Salmonella enterica in South Korea. Antimicrob. Agents Chemother., 57:2383\u20132387.","journal-title":"Antimicrob. Agents Chemother."},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1089\/fpd.2009.0376"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.2.503-511.2005"},{"key":"e_1_3_3_39_2","unstructured":"Center for Diseases Control and Prevention. 2015. Multistate Outbreak of Human Salmonella Muenchen Infections Linked to Contact with Pet Crested Geckos. Availabe at www.cdc.gov\/salmonella\/muenchen-05-15\/index.html"},{"key":"e_1_3_3_40_2","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.diagmicrobio.2016.01.016","article-title":"Presence of plasmid-mediated quinolone resistance determinants and mutations in gyrase and topoisomerase in Salmonella enterica isolates with resistance and reduced susceptibility to ciprofloxacin","volume":"85","author":"Casas M.R.T.","year":"2016","unstructured":"Casas M.R.T., , Camargo C.H., , Soares F.B., , da Silveira W.D., , and Fernandes S.A.. 2016. Presence of plasmid-mediated quinolone resistance determinants and mutations in gyrase and topoisomerase in Salmonella enterica isolates with resistance and reduced susceptibility to ciprofloxacin. Diagn. Microbiol. Infect. Dis., 85:85\u201389.","journal-title":"Diagn. Microbiol. Infect. 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