{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:26:57Z","timestamp":1777922817968,"version":"3.51.4"},"reference-count":37,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2017,7,1]],"date-time":"2017-07-01T00:00:00Z","timestamp":1498867200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:p>\n                    The antimicrobial resistance of\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    strains is rapidly increasing worldwide, which poses significant threats to animal and public health. In this study, a total of 249 porcine\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    isolates collected in China during 2008\u20132015 were examined, including 155 clinical isolates from diseased pigs and 94 nonclinical isolates from healthy pigs. Based on the minimum inhibitory concentration of seven antimicrobial agents, 96.4% of the isolates were resistant to at least one of the tested antibiotics and 81.0% of them showed multidrug resistance. The highest antimicrobial resistance was observed for tetracycline (85.9%), and the lowest was found for cefotaxime (13.3%). The isolates from diseased pigs exhibited significantly higher levels of antimicrobial resistance than those from healthy pigs. Twenty-two isolates from healthy pigs were resistant to ciprofloxacin, which may inhibit the curative effectiveness of fluoroquinolones on bacterial food-borne poisoning and infections in humans caused by contaminated food. Moreover, cefotaxime resistance of the strains isolated from diseased pigs during 2013\u20132015 was significantly higher compared with the strains isolated during 2008\u20132010. Further study showed that the correlation between phenotypic and genotypic resistance varied among the isolates from different sources, and in many cases, the presence of resistance genes was not consistent with the resistance to the corresponding antimicrobials. These results are very significant for veterinary practice and public health.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2016.0132","type":"journal-article","created":{"date-parts":[[2016,11,28]],"date-time":"2016-11-28T17:15:14Z","timestamp":1480353314000},"page":"651-659","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":19,"title":["Phenotypic and Genotypic Resistance of\n                    <i>Salmonella<\/i>\n                    Isolates from Healthy and Diseased Pigs in China During 2008\u20132015"],"prefix":"10.1177","volume":"23","author":[{"given":"Yueguang","family":"Jiu","sequence":"first","affiliation":[{"name":"Huazhong Agricultural University","place":["People's Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shun","family":"Zhu","sequence":"additional","affiliation":[{"name":"Huazhong Agricultural University","place":["People's Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sher Bahadar","family":"Khan","sequence":"additional","affiliation":[{"name":"Huazhong Agricultural University","place":["People's Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengzhen","family":"Sun","sequence":"additional","affiliation":[{"name":"Huazhong Agricultural University","place":["People's Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geng","family":"Zou","sequence":"additional","affiliation":[{"name":"Huazhong Agricultural University","place":["People's Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xianrong","family":"Meng","sequence":"additional","affiliation":[{"name":"Huazhong Agricultural University","place":["People's Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Wu","sequence":"additional","affiliation":[{"name":"Huazhong Agricultural University","place":["People's Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Zhou","sequence":"additional","affiliation":[{"name":"Huazhong Agricultural University","place":["People's Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaowen","family":"Li","sequence":"additional","affiliation":[{"name":"Huazhong Agricultural University","place":["People's Republic of China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,7]]},"reference":[{"key":"e_1_3_3_2_2","first-page":"3129","article-title":"The European Union summary report on trends and sources of zoonoses, zoonotic agents and food-borne outbreaks in 2011","volume":"11","author":"European Food Safety Authority and European Centre for Disease prevention and Control (EFSA\/ECDC)","year":"2013","unstructured":"European Food Safety Authority and European Centre for Disease prevention and Control (EFSA\/ECDC). 2013. 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