{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T06:46:19Z","timestamp":1790232379553,"version":"4.1.0"},"reference-count":43,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2017,4,5]],"date-time":"2017-04-05T00:00:00Z","timestamp":1491350400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2017,12,1]]},"abstract":"<jats:p>\n                    This study was performed to investigate the carriage rates of CTX-M-type extended-spectrum \u03b2-lactamase (ESBL)-producing\n                    <jats:italic toggle=\"yes\">Escherichia coli<\/jats:italic>\n                    among ill companion animals in Japan. Among the 178 nonrepetitive\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    isolates, including 131 from dogs and 47 from cats, collected between September and November 2015, 42 (23.6%) isolates from 29 dogs and 13 cats were identified as ESBL producers. The antimicrobial susceptibility, O serotype, phylogenetic group, \u03b2-lactamase genotype, plasmid replicon type, and sequence type (ST) of each isolate were analyzed. The major ESBL types were CTX-M-14 (26.8%), CTX-M-15 (24.4%), CTX-M-27 (19.5%), and CTX-M-55 (19.5%); predominant replicon types of\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>CTX-M<\/jats:sub>\n                    -carrying plasmid were IncF group and IncI1-I\u03b3. The most prevalent STs were ST131 (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u200915, 35.7%), followed by ST38, ST10, and ST410. The 15 isolates of ST131 belonged to B2-O25.\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    B2-O25-ST131 isolates harboring\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>CTX-M-15<\/jats:sub>\n                    or\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>CTX-M-27<\/jats:sub>\n                    were resistant to ceftazidime and ciprofloxacin. In particular, CTX-M-15 producers showed multidrug resistance. Our results demonstrated that the CTX-M-producing pandemic\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    clone B2-O25-ST131 has already spread in Japanese companion animals as well. Moreover, the similarity of genotypes, serotypes, phylogenetic groups, and STs of the isolates from companion animals to those from humans suggested probable transmission of resistant bacteria between pets and humans.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2016.0246","type":"journal-article","created":{"date-parts":[[2017,4,5]],"date-time":"2017-04-05T17:32:56Z","timestamp":1491413576000},"page":"1059-1066","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":51,"title":["Spread of CTX-Type Extended-Spectrum \u03b2-Lactamase-Producing\n                    <i>Escherichia coli<\/i>\n                    Isolates of Epidemic Clone B2-O25-ST131 Among Dogs and Cats in Japan"],"prefix":"10.1177","volume":"23","author":[{"given":"Kumiko","family":"Kawamura","sequence":"first","affiliation":[{"name":"Nagoya University Graduate School of Medicine","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae","family":"Sugawara","sequence":"additional","affiliation":[{"name":"Nagoya University Graduate School of Medicine","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nao","family":"Matsuo","sequence":"additional","affiliation":[{"name":"Nagoya University Graduate School of Medicine","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kengo","family":"Hayashi","sequence":"additional","affiliation":[{"name":"Nagoya University Graduate School of Medicine","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chihiro","family":"Norizuki","sequence":"additional","affiliation":[{"name":"Nagoya University Graduate School of Medicine","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyoko","family":"Tamai","sequence":"additional","affiliation":[{"name":"Miroku Medical Laboratory, Co., Ltd.","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takaaki","family":"Kondo","sequence":"additional","affiliation":[{"name":"Nagoya University Graduate School of Medicine","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshichika","family":"Arakawa","sequence":"additional","affiliation":[{"name":"Nagoya University Graduate School of Medicine","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,4,5]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.18.4.657-686.2005"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2007.01867.x"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2009.11.003"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(08)70041-0"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/1746-6148-8-21"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02831-10"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00656-11"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2012.03850.x"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkq472"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00002-11"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkq004"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.2012.00463.x"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiac.2013.12.003"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dks278"},{"key":"e_1_3_3_16_2","unstructured":"Clinical and Laboratory Standards Institute (CLSI). 2015. M100-S25 Performance Standards for Antimicrobial Susceptibility Testing; Twenty-fifth Informational Supplement. CLSI Wayne PA."},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.50.2.791-795.2006"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkn463"},{"key":"e_1_3_3_19_2","first-page":"53","article-title":"A preliminary survey of extended-spectrum \u03b2-lactamases (ESBLs) in clinical isolates of Klebsiella pneumoniae and Escherichia coli in Japan","volume":"184","author":"Yagi T.","year":"2000","unstructured":"Yagi T., , Kurokawa H., , Shibata N., , Shibayama K., , and Arakawa Y.. 2000. A preliminary survey of extended-spectrum \u03b2-lactamases (ESBLs) in clinical isolates of Klebsiella pneumoniae and Escherichia coli in Japan. FEMS. Microbiol. Lett., 184:53\u201356.","journal-title":"FEMS. Microbiol. Lett."},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.6.2153-2162.2002"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2014.02.019"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mimet.2005.03.018"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/1758-2229.12019"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit503"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00377-13"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01604-13"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkn084"},{"key":"e_1_3_3_28_2","unstructured":"Clinical and Laboratory Standards Institute (CLSI). 2015. M7-A10 Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically 10th ed. Approved Standard. CLSI Wayne PA."},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkm204"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00915-06"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00139-10"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.2517-6161.1995.tb02031.x"},{"key":"e_1_3_3_33_2","doi-asserted-by":"crossref","unstructured":"Agresti A. 2007. An Introduction to Categorical Data Analysis. 2nd ed. John Wiley & Sons Inc. New Jersey.","DOI":"10.1002\/0470114754"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2010.03127.x"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.2.833-835.2005"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01701-09"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.11150\/kansenshogakuzasshi1970.73.53"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02929-15"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00656-11"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkv485"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2011.05.007"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1707.110209"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dki245"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00641-13"}],"container-title":["Microbial Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/mdr.2016.0246","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2016.0246","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2016.0246","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:31:13Z","timestamp":1777667473000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/mdr.2016.0246"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,5]]},"references-count":43,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2017,12,1]]}},"alternative-id":["10.1089\/mdr.2016.0246"],"URL":"https:\/\/doi.org\/10.1089\/mdr.2016.0246","relation":{},"ISSN":["1076-6294","1931-8448"],"issn-type":[{"value":"1076-6294","type":"print"},{"value":"1931-8448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,5]]}}}