{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T10:42:08Z","timestamp":1788864128054,"version":"build-2803163510"},"reference-count":26,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2018,7,1]],"date-time":"2018-07-01T00:00:00Z","timestamp":1530403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:p>\n                    Our objective was to evaluate the performance of matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) for identification of the\n                    <jats:italic toggle=\"yes\">Chryseobacterium<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">Elizabethkingia<\/jats:italic>\n                    spp. isolated from pediatric patients at Hacettepe University Hospital using 16S rRNA gene sequencing as the gold standard and to determine the antimicrobial susceptibility patterns of the isolates and baseline characteristics of patients. All stored\n                    <jats:italic toggle=\"yes\">Chryseobacterium<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">Elizabethkingia<\/jats:italic>\n                    spp. isolated from various clinical specimens (sputum, blood, and urine) of pediatric patients at Hacettepe University Hospital between 2012 and 2016 were included in this study. Minimum inhibitory concentrations of 10 antimicrobial agents were determined by Etest for all isolates. To determine the baseline characteristics of patients, medical records of all patients were retrospectively reviewed. In total, 18 isolates of\n                    <jats:italic toggle=\"yes\">Chryseobacterium<\/jats:italic>\n                    spp. (16\n                    <jats:italic toggle=\"yes\">C. indologenes<\/jats:italic>\n                    , 2\n                    <jats:italic toggle=\"yes\">C. gleum<\/jats:italic>\n                    ) and 5 isolates of\n                    <jats:italic toggle=\"yes\">Elizabethkingia<\/jats:italic>\n                    spp. (3\n                    <jats:italic toggle=\"yes\">E. meningoseptica<\/jats:italic>\n                    , 2\n                    <jats:italic toggle=\"yes\">E. anophelis<\/jats:italic>\n                    ) were identified by 16S rRNA sequencing. MALDI-TOF MS correctly identified 19 (82.6%) isolates to the species level. The quinolones (ciprofloxacin and levofloxacin), trimethoprim\/sulfamethoxazole and piperacillin\/tazobactam showed the highest spectrum of activity against the overall collection of isolates. Cystic fibrosis (CF) was the underlying disease in 81.8% of patients. To our knowledge, this study includes the largest number of\n                    <jats:italic toggle=\"yes\">Chryseobacterium<\/jats:italic>\n                    spp. isolated from clinical specimens of pediatric patients in Turkey. In this study, we also report the first clinical isolate of\n                    <jats:italic toggle=\"yes\">E. anophelis<\/jats:italic>\n                    in Turkey. Since, the majority of strains were isolated from patients with CF; larger, prospective clinical studies are needed to establish whether chryseobacteria could be considered as an emerging opportunistic pathogen in patients with CF.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2017.0206","type":"journal-article","created":{"date-parts":[[2017,12,11]],"date-time":"2017-12-11T09:32:34Z","timestamp":1512984754000},"page":"816-821","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":27,"title":["Clinical Strains of\n                    <i>Chryseobacterium<\/i>\n                    and\n                    <i>Elizabethkingia<\/i>\n                    spp. Isolated from Pediatric Patients in a University Hospital: Performance of MALDI-TOF MS-Based Identification, Antimicrobial Susceptibilities, and Baseline Patient Characteristics"],"prefix":"10.1177","volume":"24","author":[{"given":"Hasan Cenk","family":"Mirza","sequence":"first","affiliation":[{"name":"Department of Medical Microbiology, Ba\u015fkent University Faculty of Medicine, Ankara, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d6zlem","family":"Tuncer","sequence":"additional","affiliation":[{"name":"Hacettepe University Faculty of Medicine","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serpil","family":"\u00d6lmez","sequence":"additional","affiliation":[{"name":"Hacettepe University Faculty of Medicine","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bur\u00e7in","family":"\u015eener","sequence":"additional","affiliation":[{"name":"Hacettepe University Faculty of Medicine","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00f6k\u00e7en Dil\u015fa","family":"Tu\u011fcu","sequence":"additional","affiliation":[{"name":"Hacettepe University Faculty of Medicine","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"U\u011fur","family":"\u00d6z\u00e7elik","sequence":"additional","affiliation":[{"name":"Hacettepe University Faculty of Medicine","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nafia Canan","family":"G\u00fcrsoy","sequence":"additional","affiliation":[{"name":"University Faculty of Medicine","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bar\u0131\u015f","family":"Otlu","sequence":"additional","affiliation":[{"name":"University Faculty of Medicine","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ay\u015fe","family":"B\u00fcy\u00fck\u00e7am","sequence":"additional","affiliation":[{"name":"Hacettepe University Faculty of Medicine","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ate\u015f","family":"Kara","sequence":"additional","affiliation":[{"name":"Hacettepe University Faculty of Medicine","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Banu","family":"Sancak","sequence":"additional","affiliation":[{"name":"Hacettepe University Faculty of Medicine","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,7]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1186\/s13104-016-2022-6","article-title":"Unforeseeable presentation of Chryseobacterium indologenes infection in a paediatric patient","volume":"9","author":"Srinivasan G.","year":"2016","unstructured":"Srinivasan G., , Muthusamy S., , Raveendran V., , Joseph N.M., , and Easow J.M. 2016. 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