{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:28:50Z","timestamp":1777922930742,"version":"3.51.4"},"reference-count":26,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:sec>\n                    <jats:title>Aims:<\/jats:title>\n                    <jats:p>\n                      Although the cases of macrolide-resistant\n                      <jats:italic toggle=\"yes\">Mycoplasma pneumoniae<\/jats:italic>\n                      (MRMP) have been increasing substantially among children, there are very few studies that have focused on MRMP in adults. This study aimed to investigate the prevalence and clinical features of community-acquired pneumonia (CAP) caused by MRMP from adults in Jeju Island, Korea.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      We retrospectively recruited adult patients with CAP in whom\n                      <jats:italic toggle=\"yes\">M. pneumoniae<\/jats:italic>\n                      infections had been confirmed for a 7-year period. Macrolide resistance was determined by identifying a mutation in the 23S rRNA gene using PCR.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      In total, 70 subjects were included. Their mean age was 46.1 years and 36 (51.4%) were women. Only two isolates (2.9%) carried macrolide resistance mutations in the 23S rRNA gene, and all the mutations were A2063G transitions. No significant differences were observed in age, comorbidities, symptoms, duration of fever, and length of hospital stay between the MRMP and macrolide-sensitive\n                      <jats:italic toggle=\"yes\">Mycoplasma pneumoniae<\/jats:italic>\n                      groups. The number of involved pulmonary lobes was greater in the MRMP group (3.50 vs. 1.44,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.008).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The prevalence of CAP caused by MRMP was relatively low in adults in Jeju Island. Patients with MRMP pneumonia tended to have multilobar pneumonic infiltrates.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/mdr.2018.0295","type":"journal-article","created":{"date-parts":[[2018,11,28]],"date-time":"2018-11-28T11:17:55Z","timestamp":1543403875000},"page":"577-581","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Prevalence and Clinical Features of Community-Acquired Pneumonia Caused by Macrolide-Resistant\n                    <i>Mycoplasma pneumoniae<\/i>\n                    Isolated from Adults in Jeju Island"],"prefix":"10.1177","volume":"25","author":[{"given":"Jae Hong","family":"Choi","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Jeju National University Hospital, Jeju National University School of Medicine, Jeju, Republic of Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gil Myeong","family":"Seong","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Jeju National University Hospital, Jeju National University School of Medicine, Jeju, Republic of Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yousang","family":"Ko","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Republic of Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young Ree","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Jeju National University Hospital, Jeju National University School of Medicine, Jeju, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changhwan","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Jeju National University Hospital, Jeju National University School of Medicine, Jeju, Republic of Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,5,8]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"crossref","first-page":"974","DOI":"10.3389\/fmicb.2016.00974","article-title":"Mycoplasma pneumoniae: current knowledge on macrolide resistance and treatment","volume":"7","author":"Pereyre S.","year":"2016","unstructured":"Pereyre S., , Goret J., , and Bebear C.. 2016. 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The bacterial etiology of community-acquired pneumonia in Korea: a nationwide prospective multicenter study. Infect. Chemother. 42:397\u2013403.","journal-title":"Infect. Chemother"},{"key":"e_1_3_3_5_2","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.ijantimicag.2007.09.014","article-title":"Epidemiology and clinical outcomes of community-acquired pneumonia in adult patients in Asian countries: a prospective study by the Asian network for surveillance of resistant pathogens","volume":"31","author":"Song J.H.","year":"2008","unstructured":"Song J.H., , Oh W.S., , Kang C.I., , Chung D.R., , Peck K.R., , Ko K.S., , Yeom J.S., , Kim C.K., , Kim S.W., , Chang H.H.. et al. 2008. Epidemiology and clinical outcomes of community-acquired pneumonia in adult patients in Asian countries: a prospective study by the Asian network for surveillance of resistant pathogens. Int. J. Antimicrob. Agents. 31:107\u2013114.","journal-title":"Int. J. Antimicrob. 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