{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:28:51Z","timestamp":1777922931960,"version":"3.51.4"},"reference-count":37,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2019,5,30]],"date-time":"2019-05-30T00:00:00Z","timestamp":1559174400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2019,6,1]]},"abstract":"<jats:p>\n                    The purpose of this study was to report the identification OXA-48 carbapenemase in seven extended-spectrum \u03b2-lactamase (ESBL)-positive\n                    <jats:italic toggle=\"yes\">Escherichia coli<\/jats:italic>\n                    clinical isolates, fully susceptible to all carbapenems by disk diffusion and E-test methods, but with borderline minimal inhibitory concentration (MIC) values of ertapenem. This report points to the necessity for determination of carbapenem MICs in ESBL-positive\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    isolates and additional phenotypic testing for carbapenemases in all isolates with borderline ertapenem MIC defined by EUCAST. The isolates showed a high level of resistance to expanded-spectrum cephalosporins because of the production of an additional ESBL belonging to CTX-M family. All isolates and their respective tranconjugants were found to possess L plasmid. Pulsed-field gel electrophoresis analysis revealed two clusters containing highly related isolates. The global spread of multidrug-resistant\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    should be monitored closely because of the ability of isolates to rapidly obtain additional antibiotic resistance traits such as plasmid-mediated OXA-48 genes.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2018.0309","type":"journal-article","created":{"date-parts":[[2019,1,7]],"date-time":"2019-01-07T18:36:35Z","timestamp":1546886195000},"page":"696-702","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Hidden Carbapenem Resistance in OXA-48 and Extended-Spectrum \u03b2-Lactamase-Positive\n                    <i>Escherichia coli<\/i>"],"prefix":"10.1177","volume":"25","author":[{"given":"Maja","family":"Tomi\u0107 Parad\u017eik","sequence":"first","affiliation":[{"name":"Department of Clinical Microbiology, Institute for Public Health Brod-Posavina County, Slavonski Brod, Croatia."},{"name":"School of Medicine, University of Osijek, Osijek, Croatia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domagoj","family":"Drenjan\u010devi\u0107","sequence":"additional","affiliation":[{"name":"School of Medicine, University of Osijek, Osijek, Croatia."},{"name":"University Hospital Center Osijek, Osijek, Croatia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleksandra","family":"Prese\u010dki-Stanko","sequence":"additional","affiliation":[{"name":"Department of Clinical and Molecular Microbiology, University Hospital Centre Zagreb, Zagreb, Croatia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jasminka","family":"Kopi\u0107","sequence":"additional","affiliation":[{"name":"School of Medicine, University of Osijek, Osijek, Croatia."},{"name":"Department of Anesthesiology and Intensive Care, General Hospital \u201cDr Josip Ben\u010devi\u0107,\u201d Slavonski Brod, Croatia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jasminka","family":"Talapko","sequence":"additional","affiliation":[{"name":"Faculty of Dental Medicine and Health, University of Osijek, Osijek, Croatia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gernot","family":"Zarfel","sequence":"additional","affiliation":[{"name":"Institute of Hygiene, Microbiology and Environmental Medicine, Medical University of Graz, Graz, Austria."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Branka","family":"Bedeni\u0107","sequence":"additional","affiliation":[{"name":"Department of Clinical and Molecular Microbiology, University Hospital Centre Zagreb, Zagreb, Croatia."},{"name":"School of Medicine, University of Zagreb, Zagreb, Croatia."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,5,30]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00001-07"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2012.03821.x"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.48.1.15-22.2004"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.05315-11"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01452-10"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02961-14"},{"key":"e_1_3_2_8_2","article-title":"Active surveillance scheme in three Romanian hospitals, reveals a high prevalence and variety of carbapenemase-producing Gram-negative bacteria: a pilot study, December 2014 to May 2015","volume":"21","author":"Timofte D.","year":"2017","unstructured":"Timofte D., , Panzaru C.V., , Maciuca I.E., , Dan M., , Mare A.D., , Man A., , and Toma F.. 2017. 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