{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T19:19:53Z","timestamp":1792264793378,"version":"4.4.0"},"reference-count":47,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2019,9,1]]},"abstract":"<jats:p>\n                    The aim of this study was to screen for the presence of carbapenemase-producing Enterobacteriaceae (CPE) isolates from bat guano in Bejaia, Algeria. Guano samples (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u2009110) were collected in Aokas's cave, Bejaia, Algeria, between March and May 2016. Samples were plated on MacConkey agar supplemented with ertapenem (0.5\u2009mg\/L) and vancomycin (32\u2009mg\/L). The isolates were identified and antimicrobial susceptibility was determined using disk diffusion method. Carbapenemase, extended spectrum \u03b2-lactamases, plasmid-mediated AmpC, and plasmid-mediated quinolone resistance genes were studied using PCR and sequencing. Clonal relatedness was studied using multilocus sequence typing (MLST). Two CPE isolates were identified as\n                    <jats:italic toggle=\"yes\">Klebsiella pneumoniae<\/jats:italic>\n                    . PCR and sequencing identified the\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    OXA-48 in one\n                    <jats:italic toggle=\"yes\">K. pneumoniae<\/jats:italic>\n                    strain (CS34) and\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    KPC-3 in the other strain (CS63).\n                    <jats:italic toggle=\"yes\">K. pneumoniae<\/jats:italic>\n                    CS63 was found to carry\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>TEM-1<\/jats:sub>\n                    and\n                    <jats:italic toggle=\"yes\">aac(6\u2032)-Ib<\/jats:italic>\n                    genes. The MLST showed that\n                    <jats:italic toggle=\"yes\">K. pneumoniae<\/jats:italic>\n                    CS63 was assigned to ST512, whereas\n                    <jats:italic toggle=\"yes\">K. pneumoniae<\/jats:italic>\n                    CS34 belonged to ST1878. This is the first description of CPE from bats' guano.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2018.0471","type":"journal-article","created":{"date-parts":[[2019,4,25]],"date-time":"2019-04-25T10:13:29Z","timestamp":1556187209000},"page":"1057-1062","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":26,"title":["Occurrence of Carbapenemase-Producing\n                    <i>Klebsiella pneumoniae<\/i>\n                    in Bat Guano"],"prefix":"10.1177","volume":"25","author":[{"given":"Alima","family":"Gharout-Sait","sequence":"first","affiliation":[{"name":"Laboratoire d'Ecologie Microbienne, FSNV, Universit\u00e9 de Bejaia, Bejaia, Alg\u00e9rie."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdelaziz","family":"Touati","sequence":"additional","affiliation":[{"name":"Laboratoire d'Ecologie Microbienne, FSNV, Universit\u00e9 de Bejaia, Bejaia, Alg\u00e9rie."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mourad","family":"Ahmim","sequence":"additional","affiliation":[{"name":"Laboratoire d'Ecologie et d'Environnement, FSNV, Universit\u00e9 de Bejaia, Bejaia, Alg\u00e9rie."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucien","family":"Brasme","sequence":"additional","affiliation":[{"name":"Laboratoire de Bact\u00e9riologie, Virologie-Hygi\u00e8ne Hospitali\u00e8re, CHU Reims, H\u00f4pital Robert DEBRE, Avenue du G\u00e9n\u00e9ral Koenig, Reims, France."},{"name":"Inserm UMR-S 1250 P3Cell, SFR CAP-Sant\u00e9, Universit\u00e9 de Reims Champagne-Ardenne, Reims, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Guillard","sequence":"additional","affiliation":[{"name":"Laboratoire de Bact\u00e9riologie, Virologie-Hygi\u00e8ne Hospitali\u00e8re, CHU Reims, H\u00f4pital Robert DEBRE, Avenue du G\u00e9n\u00e9ral Koenig, Reims, France."},{"name":"Inserm UMR-S 1250 P3Cell, SFR CAP-Sant\u00e9, Universit\u00e9 de Reims Champagne-Ardenne, Reims, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Agsous","sequence":"additional","affiliation":[{"name":"Laboratoire d'Ecologie Microbienne, FSNV, Universit\u00e9 de Bejaia, Bejaia, Alg\u00e9rie."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"de Champs","sequence":"additional","affiliation":[{"name":"Laboratoire de Bact\u00e9riologie, Virologie-Hygi\u00e8ne Hospitali\u00e8re, CHU Reims, H\u00f4pital Robert DEBRE, Avenue du G\u00e9n\u00e9ral Koenig, Reims, France."},{"name":"Inserm UMR-S 1250 P3Cell, SFR CAP-Sant\u00e9, Universit\u00e9 de Reims Champagne-Ardenne, Reims, France."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,9,9]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2015.20.45.30062"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcma.2017.08.015"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.45.4.1151-1161.2001"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.2807\/ese.18.22.20489-en"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01019-15"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.2017.0168"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.24272\/j.issn.2095-8137.2017.024"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.3402\/ehtj.v4i0.7159"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-12-279"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1590\/0074-02760150048"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.11609\/jott.2576.9.1.9723-9733"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.1988.0129"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00871-16"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1086\/600885"},{"key":"e_1_3_3_16_2","unstructured":"Comit\u00e9 de l\u2032antibiogramme de la Soci\u00e9t\u00e9 Fran\u00e7aise de Microbiologie. 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