{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:29:42Z","timestamp":1777922982083,"version":"3.51.4"},"reference-count":26,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:p>\n                    The spread of carbapenem-resistant\n                    <jats:italic toggle=\"yes\">Klebsiella pneumoniae<\/jats:italic>\n                    has become a significant problem for public health in recent years. In this study, we reported a New Delhi metallo-\u03b2-lactamase 1 (NDM-1)-producing\n                    <jats:italic toggle=\"yes\">K. pneumoniae<\/jats:italic>\n                    strain KP14003 from a neonate in Beijing, China. Whole-genome sequencing was performed. The strain belonged to sequence type ST719. Coexistence of\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>NDM-1<\/jats:sub>\n                    and\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>SHV-12<\/jats:sub>\n                    was found on a self-transferable plasmid, which had a typical IncX3 backbone. The horizontal transfer of\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>NDM-1<\/jats:sub>\n                    was associated with Tn\n                    <jats:italic toggle=\"yes\">125<\/jats:italic>\n                    followed by possible transposition events. Other class A extended-spectrum \u03b2-lactamase genes (\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>SHV-27<\/jats:sub>\n                    and\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>TEM-1<\/jats:sub>\n                    ) were also identified on chromosome or plasmid. The dissemination of NDM-1-producing\n                    <jats:italic toggle=\"yes\">K. pneumoniae<\/jats:italic>\n                    causes great challenges to the treatment of clinical infections. Effective actions need to be taken to control the further spread of this pathogen.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2019.0058","type":"journal-article","created":{"date-parts":[[2019,11,15]],"date-time":"2019-11-15T14:59:56Z","timestamp":1573829996000},"page":"492-496","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["New Delhi Metallo-\u03b2-Lactamase 1-Producing\n                    <i>Klebsiella pneumoniae<\/i>\n                    ST719 Isolated from a Neonate in China"],"prefix":"10.1177","volume":"26","author":[{"given":"Jinhui","family":"Li","sequence":"first","affiliation":[{"name":"Center for Disease Control and Prevention of PLA, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaofeng","family":"Hu","sequence":"additional","affiliation":[{"name":"Center for Disease Control and Prevention of PLA, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lang","family":"Yang","sequence":"additional","affiliation":[{"name":"Center for Disease Control and Prevention of PLA, Beijing, China."},{"name":"Academy of Military Medical Sciences, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanfeng","family":"Lin","sequence":"additional","affiliation":[{"name":"Center for Disease Control and Prevention of PLA, Beijing, China."},{"name":"Academy of Military Medical Sciences, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuqi","family":"Liu","sequence":"additional","affiliation":[{"name":"Center for Disease Control and Prevention of PLA, Beijing, China."},{"name":"Academy of Military Medical Sciences, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peihan","family":"Li","sequence":"additional","affiliation":[{"name":"Center for Disease Control and Prevention of PLA, Beijing, China."},{"name":"Academy of Military Medical Sciences, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaiying","family":"Wang","sequence":"additional","affiliation":[{"name":"Center for Disease Control and Prevention of PLA, Beijing, China."},{"name":"Academy of Military Medical Sciences, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaofu","family":"Qiu","sequence":"additional","affiliation":[{"name":"Center for Disease Control and Prevention of PLA, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peng","family":"Li","sequence":"additional","affiliation":[{"name":"Center for Disease Control and Prevention of PLA, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongbin","family":"Song","sequence":"additional","affiliation":[{"name":"Center for Disease Control and Prevention of PLA, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,5,7]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1017\/S0195941700062639","article-title":"The epidemiology of nosocomial infections caused by Klebsiella pneumoniae","volume":"6","author":"Jarvis W.R.","year":"1985","unstructured":"Jarvis W.R., , Munn V.P, , Highsmith A.K, , Culver D.H, , and Hughes J.M.. 1985. The epidemiology of nosocomial infections caused by Klebsiella pneumoniae. Infect. Control, 6:68\u201374.","journal-title":"Infect. Control"},{"key":"e_1_3_3_3_2","first-page":"5046","volume-title":"Antimicrob. Agents Chemother","author":"Yong D.","year":"2009","unstructured":"Yong D., , Toleman M.A, , Giske C.G, , Cho H.S, , Sundman K., , Lee K., , and Walsh T.R. 2009. Characterization of a new metallo-beta-lactamase gene, blaNDM-1, and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India. Antimicrob. Agents Chemother. 53:5046\u20135054."},{"key":"e_1_3_3_4_2","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.diagmicrobio.2013.01.006","article-title":"Emergence of bla\n                  NDM-1 among Klebsiella pneumoniae ST15 and novel ST1031 clinical isolates in China","volume":"75","author":"Hu L.","year":"2013","unstructured":"Hu L., , Zhong Q., , Tu J., , Xu Y., , Qin Z., , Parsons C., , Zhang B., , Hu X., , Wang L., , Yu F., , and Pan J.. 2013. Emergence of blaNDM-1 among Klebsiella pneumoniae ST15 and novel ST1031 clinical isolates in China. Diagn. Microbiol. Infect. Dis. 75:373\u2013376.","journal-title":"Diagn. Microbiol. Infect. 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