{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T12:07:31Z","timestamp":1788955651165,"version":"build-2803163510"},"reference-count":40,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2019,10,31]],"date-time":"2019-10-31T00:00:00Z","timestamp":1572480000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:p>\n                    Of all the\n                    <jats:italic toggle=\"yes\">Proteus<\/jats:italic>\n                    spp.,\n                    <jats:italic toggle=\"yes\">Proteus mirabilis<\/jats:italic>\n                    is the most common species identified in clinical specimens and is a leading agent of complicated urinary tract infection. This study was undertaken to understand the antimicrobial susceptibility, prevalence of antibiotic resistance genes, and molecular typing of\n                    <jats:italic toggle=\"yes\">P. mirabilis<\/jats:italic>\n                    isolates collected from three hospitals in northern Taiwan. The results showed that the collected isolates of\n                    <jats:italic toggle=\"yes\">P. mirabilis<\/jats:italic>\n                    were susceptible to most antibiotics except cefazolin and tigecycline. Many resistance genes were detected in the collected isolates, of which TEM genes were the most common. Resistance to third- or fourth-generation cephalosporins was related to the presence of at least one of the tested extended-spectrum \u03b2-lactamase (ESBL) or AmpC genes. The presence of the VEB-1 gene seemed to be a good predictor for both cefepime and ceftazidime resistance, which was further supported by quantitative polymerase chain reaction results. Of the four imipenem-resistant\n                    <jats:italic toggle=\"yes\">P. mirabilis<\/jats:italic>\n                    isolates, three isolates could hydrolyze imipenem by mass spectrometry analysis. Molecular typing by pulsed-field gel electrophoresis showed that the pulsotyping of the selected\n                    <jats:italic toggle=\"yes\">P. mirabilis<\/jats:italic>\n                    isolates was heterogeneous. By analyzing the relationship of antimicrobial resistance and the presence of resistance genes, revision of the Clinical and Laboratory Standards Institute cefepime and ceftazidime MIC breakpoints for Enterobacteriaceae to predict ESBL producers might possibly be needed.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2019.0066","type":"journal-article","created":{"date-parts":[[2019,7,11]],"date-time":"2019-07-11T14:15:37Z","timestamp":1562854537000},"page":"1338-1346","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Antimicrobial Susceptibility and Molecular Epidemiology of\n                    <i>Proteus mirabilis<\/i>\n                    Isolates from Three Hospitals in Northern Taiwan"],"prefix":"10.1177","volume":"25","author":[{"given":"Ming-Feng","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Medicine, National Taiwan University Hospital Chu-Tung Branch, Hsin-Chu, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Li","family":"Liou","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Science and Biotechnology, Yuanpei University, Hsin-Chu, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiung-Hui","family":"Kuo","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, National Taiwan University Hospital Chu-Tung Branch, Hsin-Chu, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun-You","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Science and Biotechnology, Yuanpei University, Hsin-Chu, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiann-Yuan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Taipei Hospital, Ministry of Health and Welfare, New Taipei, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han-Yueh","family":"Kuo","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, National Taiwan University Hospital Hsin-Chu Branch, Hsin-Chu, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,10,31]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00019-07"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2890"},{"key":"e_1_3_4_4_2","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1179\/joc.2003.15.1.12","article-title":"Natural antibiotic susceptibility of Proteus spp., with special reference to P. mirabilis and P. penneri strains","volume":"15","author":"Stock I.","year":"2003","unstructured":"Stock I. 2003. Natural antibiotic susceptibility of Proteus spp., with special reference to P. mirabilis and P. penneri strains. J. Chemother. 15:12\u201326.","journal-title":"J. Chemother"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2013.11.025"},{"key":"e_1_3_4_6_2","doi-asserted-by":"crossref","first-page":"3127","DOI":"10.1128\/JCM.00222-11","article-title":"Susceptibility of extended-spectrum-beta-lactamase-producing Enterobacteriaceae according to the new CLSI breakpoints","volume":"49","author":"Wang P.","year":"2011","unstructured":"Wang P., , Hu F., , Xiong Z., , Ye X., , Zhu D., , Wang Y.F, , and Wang M. 2011. Susceptibility of extended-spectrum-beta-lactamase-producing Enterobacteriaceae according to the new CLSI breakpoints. J. Clin. Microbiol. 49:3127\u20133131.","journal-title":"J. Clin. Microbiol"},{"key":"e_1_3_4_7_2","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1093\/jac\/dkn056","article-title":"Increase in beta-lactam-resistant Proteus mirabilis strains due to CTX-M- and CMY-type as well as new VEB- and inhibitor-resistant TEM-type beta-lactamases","volume":"61","author":"Aragon L.M.","year":"2008","unstructured":"Aragon L.M., , Mirelis B., , Miro E., , Mata C., , Gomez L., , Rivera A., , Coll P., , and Navarro F. 2008. Increase in beta-lactam-resistant Proteus mirabilis strains due to CTX-M- and CMY-type as well as new VEB- and inhibitor-resistant TEM-type beta-lactamases. J. Antimicrob. Chemother. 61:1029\u20131032.","journal-title":"J. Antimicrob. Chemother"},{"key":"e_1_3_4_8_2","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1099\/jmm.0.068981-0","article-title":"Evaluation of the Clinical and Laboratory Standards Institute phenotypic confirmatory test to detect the presence of extended-spectrum beta-lactamases from 4005 Escherichia coli, Klebsiella oxytoca, Klebsiella pneumoniae and Proteus mirabilis isolates","volume":"63","author":"Morrissey I.","year":"2014","unstructured":"Morrissey I., , Bouchillon S.K, , Hackel M., , Biedenbach D.J, , Hawser S., , Hoban D., , and Badal R.E. 2014. Evaluation of the Clinical and Laboratory Standards Institute phenotypic confirmatory test to detect the presence of extended-spectrum beta-lactamases from 4005 Escherichia coli, Klebsiella oxytoca, Klebsiella pneumoniae and Proteus mirabilis isolates. J. Med. Microbiol. 63:556\u2013561.","journal-title":"J. Med. Microbiol"},{"key":"e_1_3_4_9_2","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1128\/JCM.42.4.1542-1546.2004","article-title":"Evaluation of the automated phoenix system for potential routine use in the clinical microbiology laboratory","volume":"42","author":"Donay J.L.","year":"2004","unstructured":"Donay J.L., , Mathieu D., , Fernandes P., , Pregermain C., , Bruel P., , Wargnier A., , Casin I., , Weill F.X, , Lagrange P.H, , and Herrmann J.L. 2004. Evaluation of the automated phoenix system for potential routine use in the clinical microbiology laboratory. J. Clin. Microbiol. 42:1542\u20131546.","journal-title":"J. Clin. Microbiol"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkp498"},{"key":"e_1_3_4_11_2","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1186\/1471-2164-15-815","article-title":"Transcriptome profiling in imipenem-selected Acinetobacter baumannii","volume":"15","author":"Chang K.C.","year":"2014","unstructured":"Chang K.C., , Kuo H.Y, , Tang C.Y, , Chang C.W, , Lu C.W, , Liu C.C, , Lin H.R, , Chen K.H, , and Liou M.L. 2014. Transcriptome profiling in imipenem-selected Acinetobacter baumannii. BMC Genomics, 15:815.","journal-title":"BMC Genomics"},{"key":"e_1_3_4_12_2","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.jhin.2004.07.007","article-title":"Antibiotic susceptibility and REP-PCR fingerprints of Acinetobacter spp. isolated from a hospital ten years apart","volume":"58","author":"Misbah S.","year":"2004","unstructured":"Misbah S., , AbuBakar S., , Hassan H., , Hanifah Y.A, , and Yusof M.Y. 2004. Antibiotic susceptibility and REP-PCR fingerprints of Acinetobacter spp. isolated from a hospital ten years apart. J. Hosp. Infect. 58:254\u2013261.","journal-title":"J. Hosp. Infect"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.11.4961-4965.2003"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.13.4.534-546.2000"},{"key":"e_1_3_4_15_2","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1186\/1471-2334-14-486","article-title":"Antimicrobial susceptibilities of Proteus mirabilis: a longitudinal nationwide study from the Taiwan surveillance of antimicrobial resistance (TSAR) program","volume":"14","author":"Wang J.T.","year":"2014","unstructured":"Wang J.T., , Chen P.C, , Chang S.C, , Shiau Y.R, , Wang H.Y, , Lai J.F, , Huang I.W, , Tan M.C, , and Lauderdale T.L. 2014. Antimicrobial susceptibilities of Proteus mirabilis: a longitudinal nationwide study from the Taiwan surveillance of antimicrobial resistance (TSAR) program. BMC Infect. Dis. 14:486.","journal-title":"BMC Infect. Dis"},{"key":"e_1_3_4_16_2","doi-asserted-by":"crossref","first-page":"267","DOI":"10.4103\/amhsr.amhsr_413_15","article-title":"Phenotypic detection and antibiogram of beta-lactamase-producing Proteus species in a Tertiary Care Hospital, India","volume":"6","author":"Pal N.","year":"2016","unstructured":"Pal N., , Hooja S., , Sharma R., , and Maheshwari R.K. 2016. Phenotypic detection and antibiogram of beta-lactamase-producing Proteus species in a Tertiary Care Hospital, India. Ann. Med. Health Sci. Res. 6:267\u2013273.","journal-title":"Ann. Med. Health Sci. Res"},{"key":"e_1_3_4_17_2","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1159\/000316332","article-title":"Emergence of Proteus mirabilis isolates producing TEM-52 extended-spectrum beta-lactamases in Croatia","volume":"56","author":"Sardelic S.","year":"2010","unstructured":"Sardelic S., , Bedenic B., , Sijak D., , Colinon C., , and Kalenic S. 2010. Emergence of Proteus mirabilis isolates producing TEM-52 extended-spectrum beta-lactamases in Croatia. Chemotherapy, 56:208\u2013213.","journal-title":"Chemotherapy"},{"key":"e_1_3_4_18_2","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.jinf.2013.09.001","article-title":"Susceptibility of gram-negative aerobic bacilli from intra-abdominal pathogens to antimicrobial agents collected in the United States during 2011","volume":"68","author":"Hawser S.P.","year":"2014","unstructured":"Hawser S.P., , Badal R.E, , Bouchillon S.K, , Hoban D.J, , Hackel M.A, , Biedenbach D.J, , and Goff D.A. 2014. Susceptibility of gram-negative aerobic bacilli from intra-abdominal pathogens to antimicrobial agents collected in the United States during 2011. J. Infect. 68:71\u201376.","journal-title":"J. Infect"},{"key":"e_1_3_4_19_2","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1128\/AAC.01835-09","article-title":"Chromosome-encoded AmpC and CTX-M extended-spectrum beta-lactamases in clinical isolates of Proteus mirabilis from Korea","volume":"55","author":"Song W.","year":"2011","unstructured":"Song W., , Kim J., , Bae I.K, , Jeong S.H, , Seo Y.H, , Shin J.H, , Jang S.J, , Uh Y., , Shin J.H, , Lee M.K, , and Lee K. 2011. Chromosome-encoded AmpC and CTX-M extended-spectrum beta-lactamases in clinical isolates of Proteus mirabilis from Korea. Antimicrob. Agents Chemother. 55:1414\u20131419.","journal-title":"Antimicrob. Agents Chemother"},{"key":"e_1_3_4_20_2","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.ijantimicag.2010.06.002","article-title":"Rapidly spreading CTX-M-type beta-lactamase-producing Proteus mirabilis in Japan","volume":"36","author":"Kanayama A.","year":"2010","unstructured":"Kanayama A., , Iyoda T., , Matsuzaki K., , Saika T., , Ikeda F., , Ishii Y., , Yamaguchi K., , and Kobayashi I. 2010. Rapidly spreading CTX-M-type beta-lactamase-producing Proteus mirabilis in Japan. Int. J. Antimicrob. Agents, 36:340\u2013342.","journal-title":"Int. J. Antimicrob. Agents"},{"key":"e_1_3_4_21_2","doi-asserted-by":"crossref","first-page":"E51","DOI":"10.1111\/1469-0691.12072","article-title":"A binational cohort study of intestinal colonization with extended-spectrum beta-lactamase-producing Proteus mirabilis in patients admitted to rehabilitation centres","volume":"19","author":"Adler A.","year":"2013","unstructured":"Adler A., , Baraniak A., , Izdebski R., , Fiett J., , Gniadkowski M., , Hryniewicz W., , Salvia A., , Rossini A., , Goossens H., , Malhotra S., , Lerman Y., , Elenbogen M., , and Carmeli Y. 2013. A binational cohort study of intestinal colonization with extended-spectrum beta-lactamase-producing Proteus mirabilis in patients admitted to rehabilitation centres. Clin. Microbiol. Infect. 19:E51\u2013E58.","journal-title":"Clin. Microbiol. Infect"},{"key":"e_1_3_4_22_2","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.1099\/jmm.0.049726-0","article-title":"Regional outbreak of CTX-M-2 beta-lactamase-producing Proteus mirabilis in Japan","volume":"61","author":"Nakano R.","year":"2012","unstructured":"Nakano R., , Nakano A., , Abe M., , Inoue M., , and Okamoto R. 2012. Regional outbreak of CTX-M-2 beta-lactamase-producing Proteus mirabilis in Japan. J. Med. Microbiol. 61:1727\u20131735.","journal-title":"J. Med. Microbiol"},{"key":"e_1_3_4_23_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkr286"},{"key":"e_1_3_4_24_2","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1093\/jac\/46.5.703","article-title":"Integron-located VEB-1 extended-spectrum beta-lactamase gene in a Proteus mirabilis clinical isolate from Vietnam","volume":"46","author":"Naas T.","year":"2000","unstructured":"Naas T., , Benaoudia F., , Massuard S., , and Nordmann P. 2000. Integron-located VEB-1 extended-spectrum beta-lactamase gene in a Proteus mirabilis clinical isolate from Vietnam. J. Antimicrob. Chemother. 46:703\u2013711.","journal-title":"J. Antimicrob. Chemother"},{"key":"e_1_3_4_25_2","doi-asserted-by":"crossref","first-page":"4024","DOI":"10.1128\/AAC.00470-12","article-title":"Characterization of a transmissible plasmid encoding VEB-1 and VIM-1 in Proteus mirabilis","volume":"56","author":"Papagiannitsis C.C.","year":"2012","unstructured":"Papagiannitsis C.C., , Miriagou V., , Kotsakis S.D, , Tzelepi E., , Vatopoulos A.C, , Petinaki E., , and Tzouvelekis L.S. 2012. Characterization of a transmissible plasmid encoding VEB-1 and VIM-1 in Proteus mirabilis. Antimicrob. Agents Chemother. 56:4024\u20134025.","journal-title":"Antimicrob. Agents Chemother"},{"key":"e_1_3_4_26_2","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.016964-0"},{"key":"e_1_3_4_27_2","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1128\/JCM.40.4.1549-1552.2002","article-title":"Emerging extended-spectrum beta-lactamases in Proteus mirabilis","volume":"40","author":"Pagani L.","year":"2002","unstructured":"Pagani L., , Migliavacca R., , Pallecchi L., , Matti C., , Giacobone E., , Amicosante G., , Romero E., , and Rossolini G.M. 2002. Emerging extended-spectrum beta-lactamases in Proteus mirabilis. J. Clin. Microbiol. 40:1549\u20131552.","journal-title":"J. Clin. Microbiol"},{"key":"e_1_3_4_28_2","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1128\/AAC.01450-13","article-title":"Detection of CMY-99, a novel acquired AmpC-type beta-lactamase, and VIM-1 in Proteus mirabilis isolates in Bulgaria","volume":"58","author":"Schneider I.","year":"2014","unstructured":"Schneider I., , Markovska R., , Marteva-Proevska Y., , Mitov I., , Markova B., , and Bauernfeind A. 2014. Detection of CMY-99, a novel acquired AmpC-type beta-lactamase, and VIM-1 in Proteus mirabilis isolates in Bulgaria. Antimicrob. Agents Chemother. 58:620\u2013621.","journal-title":"Antimicrob. Agents Chemother"},{"key":"e_1_3_4_29_2","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1128\/AAC.42.6.1350","article-title":"Beta-lactamases responsible for resistance to expanded-spectrum cephalosporins in Klebsiella pneumoniae, Escherichia coli, and Proteus mirabilis isolates recovered in South Africa","volume":"42","author":"Pitout J.D.","year":"1998","unstructured":"Pitout J.D., , Thomson K.S, , Hanson N.D, , Ehrhardt A.F, , Moland E.S, , and Sanders C.C. 1998. Beta-lactamases responsible for resistance to expanded-spectrum cephalosporins in Klebsiella pneumoniae, Escherichia coli, and Proteus mirabilis isolates recovered in South Africa. Antimicrob. Agents Chemother. 42:1350\u20131354.","journal-title":"Antimicrob. Agents Chemother"},{"key":"e_1_3_4_30_2","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1093\/jac\/48.3.383","article-title":"CMY-2-producing Salmonella enterica, Klebsiella pneumoniae, Klebsiella oxytoca, Proteus mirabilis and Escherichia coli strains isolated in Spain (October 1999\u2013December 2000)","volume":"48","author":"Navarro F.","year":"2001","unstructured":"Navarro F., , Perez-Trallero E., , Marimon J.M, , Aliaga R., , Gomariz M., , and Mirelis B. 2001. CMY-2-producing Salmonella enterica, Klebsiella pneumoniae, Klebsiella oxytoca, Proteus mirabilis and Escherichia coli strains isolated in Spain (October 1999\u2013December 2000). J. Antimicrob. Chemother. 48:383\u2013389.","journal-title":"J. Antimicrob. Chemother"},{"key":"e_1_3_4_31_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.46.1.1-11.2002"},{"key":"e_1_3_4_32_2","doi-asserted-by":"crossref","first-page":"2735","DOI":"10.1128\/AAC.01736-10","article-title":"Evolution and spread of a multidrug-resistant Proteus mirabilis clone with chromosomal AmpC-type cephalosporinases in Europe","volume":"55","author":"D'Andrea M.M.","year":"2011","unstructured":"D'Andrea M.M., , Literacka E., , Zioga A., , Giani T., , Baraniak A., , Fiett J., , Sadowy E., , Tassios P.T, , Rossolini G.M, , Gniadkowski M., , and Miriagou V. 2011. Evolution and spread of a multidrug-resistant Proteus mirabilis clone with chromosomal AmpC-type cephalosporinases in Europe. Antimicrob. Agents Chemother. 55:2735\u20132742.","journal-title":"Antimicrob. Agents Chemother"},{"key":"e_1_3_4_33_2","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.jmii.2013.07.002","article-title":"Relationship between the distribution of cefepime minimum inhibitory concentrations and detection of extended-spectrum beta-lactamase production among clinically important Enterobacteriaceae isolates obtained from patients in intensive care units in Taiwan: results from the Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART) in 2007","volume":"48","author":"Jean S.S.","year":"2015","unstructured":"Jean S.S., , Lee W.S, , Bai K.J, , Lam C., , Hsu C.W, , Yu K.W, , Liao C.H, , Chang F.Y, , Ko W.C, , Wu J.J, , Chen Y.H, , Chen Y.S, , Liu J.W, , Lu M.C, , Liu C.Y, , Chen R.J, , and Hsueh P.R. 2015. Relationship between the distribution of cefepime minimum inhibitory concentrations and detection of extended-spectrum beta-lactamase production among clinically important Enterobacteriaceae isolates obtained from patients in intensive care units in Taiwan: results from the Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART) in 2007. J. Microbiol. Immunol. Infect. 48:85\u201391.","journal-title":"J. Microbiol. Immunol. Infect"},{"key":"e_1_3_4_34_2","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1179\/joc.2010.22.3.147","article-title":"Antimicrobial susceptibility and beta-lactamase production of selected gram-negative bacilli from two Croatian hospitals: MYSTIC study results","volume":"22","author":"Bedenic B.","year":"2010","unstructured":"Bedenic B., , Goic-Barisic I., , Budimir A., , Tonkic M., , Mihajkevic L.J, , Novak A., , Sviben M., , Plecko V., , Punda-Polic V., , and Kalenic S. 2010. Antimicrobial susceptibility and beta-lactamase production of selected gram-negative bacilli from two Croatian hospitals: MYSTIC study results. J. Chemother. 22:147\u2013152.","journal-title":"J. Chemother"},{"key":"e_1_3_4_35_2","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.diagmicrobio.2014.07.006","article-title":"Carbapenems and piperacillin\/tazobactam for the treatment of bacteremia caused by extended-spectrum beta-lactamase-producing Proteus mirabilis","volume":"80","author":"Tsai H.Y.","year":"2014","unstructured":"Tsai H.Y., , Chen Y.H, , Tang H.J, , Huang C.C, , Liao C.H, , Chu F.Y, , Chuang Y.C, , Sheng W.H, , Ko W.C, , and Hsueh P.R. 2014. Carbapenems and piperacillin\/tazobactam for the treatment of bacteremia caused by extended-spectrum beta-lactamase-producing Proteus mirabilis. Diagn. Microbiol. Infect. Dis. 80:222\u2013226.","journal-title":"Diagn. Microbiol. Infect. Dis"},{"key":"e_1_3_4_36_2","unstructured":"CLSI. 2010. Performance Standards for Antimicrobial Susceptibility Testing; Twenty Informational Supplement. CLSI Document M100-S120. Clinical and Laboratory Standards Institute Wayne PA."},{"key":"e_1_3_4_37_2","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1155\/2014\/265981","article-title":"Effects of breakpoint changes on carbapenem susceptibility rates of Enterobacteriaceae: results from the SENTRY Antimicrobial Surveillance Program, United States, 2008 to 2012","volume":"25","author":"Rennie R.P.","year":"2014","unstructured":"Rennie R.P., , and Jones R.N. 2014. Effects of breakpoint changes on carbapenem susceptibility rates of Enterobacteriaceae: results from the SENTRY Antimicrobial Surveillance Program, United States, 2008 to 2012. Can J. Infect. Dis. Med. Microbiol. 25:285\u2013287.","journal-title":"Can J. Infect. Dis. Med. Microbiol"},{"key":"e_1_3_4_38_2","unstructured":"CLSI. 2018. Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Seventh Informational Supplement. CLSI Document M100. Clinical and Laboratory Standards Institute Wayne PA."},{"key":"e_1_3_4_39_2","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.jiac.2016.12.013","article-title":"Molecular epidemiology of carbapenemase-producing Enterobacteriaceae in a primary care hospital in Japan, 2010\u20132013","volume":"23","author":"Ohno Y.","year":"2017","unstructured":"Ohno Y., , Nakamura A., , Hashimoto E., , Matsutani H., , Abe N., , Fukuda S., , Hisashi K., , Komatsu M., , and Nakamura F. 2017. Molecular epidemiology of carbapenemase-producing Enterobacteriaceae in a primary care hospital in Japan, 2010\u20132013. J. Infect. Chemother. 23:224\u2013229.","journal-title":"J. Infect. Chemother"},{"key":"e_1_3_4_40_2","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1128\/AAC.46.6.2004-2006.2002","article-title":"Chromosome-encoded class D beta-lactamase OXA-23 in Proteus mirabilis","volume":"46","author":"Bonnet R.","year":"2002","unstructured":"Bonnet R., , Marchandin H., , Chanal C., , Sirot D., , Labia R., , De Champs C., , Jumas-Bilak E., , and Sirot J. 2002. Chromosome-encoded class D beta-lactamase OXA-23 in Proteus mirabilis. Antimicrob. Agents Chemother. 46:2004\u20132006.","journal-title":"Antimicrob. Agents Chemother"},{"key":"e_1_3_4_41_2","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1111\/j.1469-0691.2010.03225.x","article-title":"Metallo-beta-lactamases among Enterobacteriaceae from routine samples in an Italian tertiary-care hospital and long-term care facilities during 2008","volume":"17","author":"Aschbacher R.","year":"2011","unstructured":"Aschbacher R., , Pagani L., , Doumith M., , Pike R., , Woodford N., , Spoladore G., , Larcher C., , and Livermore D.M. 2011. Metallo-beta-lactamases among Enterobacteriaceae from routine samples in an Italian tertiary-care hospital and long-term care facilities during 2008. Clin. Microbiol. Infect. 17:181\u2013189.","journal-title":"Clin. Microbiol. Infect"}],"container-title":["Microbial Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/mdr.2019.0066","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2019.0066","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2019.0066","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:35:30Z","timestamp":1777667730000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/mdr.2019.0066"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,31]]},"references-count":40,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2019,11]]}},"alternative-id":["10.1089\/mdr.2019.0066"],"URL":"https:\/\/doi.org\/10.1089\/mdr.2019.0066","relation":{},"ISSN":["1076-6294","1931-8448"],"issn-type":[{"value":"1076-6294","type":"print"},{"value":"1931-8448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,31]]}}}